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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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      "text": "Patient inquiries are muted; docs will use generic if they think diazoxide is useful; lukewarm interest in trying a few patients",
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      "text": "I haven't had emails from my patients or patients' families, which is very interesting, even though this is a pretty active community. So, that's just interesting, but I haven't, and that's maybe telling",
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      "text": "“Furious” about “outrageous” cost; can get same appetite suppression for pennies\n“I think it's something like $400k a year or something outrageous…I imagine quite a lot of my patients, in fact, all of them are probably over 100 kilos. And that probably pushes me starting, starting about 150…of course, it bothers me. It makes me mad, maybe even furious, about these outrageous costs. Because ultimately, this degree of appetite suppression could be readily achieved with sedating medications like Haldol and other antipsychotics, for example, which have their own diabetogenic risk for the cost of pennies.” – Endocrinologist with academic and community hospital affiliations",
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      "text": "“I haven't had emails from my patients or patients' families, which is very interesting, even though this is a pretty active community. So, that's just interesting, but I haven't, and that's maybe telling that there is maybe less either awareness or enthusiasm amongst the patient population or their families. I suspect what will happen is that there will be a variety of attempts to prescribe, start forms issued, initial experience, and then what to do with those for non-accessible patients and for patients who do respond. I think the next steps will probably be a lot will come off the branded version onto generic if it works. And for patients who are declined because of access reasons, efforts to try unbranded diazoxide and then an evaluation kind of in the next few weeks and months as to whether this approach is adequately balanced with the safety and efficacy in a way that might create an opportunity we haven't had before, or whether this is all hoopla and bluster.” -Endocrinologist; academic and community hospital affiliations.",
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      "text": "“I think it’s something like $400k a year or something outrageous…I imagine quite a lot of my patients, in fact, all of them are probably over 100 kilos. And that probably pushes me starting, starting about 150…of course, it bothers me. It makes me mad, maybe even furious, about these outrageous costs. Because ultimately, this degree of appetite suppression could be readily achieved with sedating medications like Haldol and other antipsychotics, for example, which have their own diabetogenic risk for the cost of pennies.” — Endocrinologist with academic and community hospital affiliations.",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "Endocrinologist #1: Zero emails from PWS patients inquiring about Vykat; if Vykat were theoretically useful, he would quickly put them on generic diazoxide suspension anyway; questions “whether this is all hoopla and bluster”; is “furious” about the price and finds it “outrageous” – “it bothers me, it makes me mad” as appetite suppression can be obtained for “pennies” with other medications – “I haven't had emails from my patients or patients' families, which is very interesting, even though this is a pretty active community. So, that's just interesting, but I haven't, and that's maybe telling”; “a lot will come off the branded version onto generic if it works”; “appetite suppression could be readily achieved with sedating medications like Haldol and other antipsychotics, for example, which have their own diabetogenic risk for the cost of pennies.”",
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