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      "text": "Discontinued due to risk of diabetes; went on metformin",
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      "text": "Will put very few PWS patients on it; diabetes risk \"is quite an issue\" and further limits the TAM",
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      "text": "Q: \"How many of those do you plan to put on Vykat?\" A: \"Quite a few of my cohort is below the age of four... I will be careful with patients that have impaired glucose tolerance because then to type 2 diabetes, I think, is quite an issue.\"",
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      "text": "When we asked how many of the investigator's 35 PWS patients were likely to be prescribed the drug, the investigator evaded the question with an indirect but telling answer...",
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      "text": "Q: \"What was the adverse effect that led the patient to discontinue?\" A: \"It was a drug reaction... we had suggested starting metformin...\" Q: \"You were worried enough about the blood sugar elevation to put the patient on metformin?\" A: \"I was worried about the glucose increase...\"",
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      "text": "“I will be careful with patients that have impaired glucose tolerance because then type 2 diabetes, I think, is quite an issue.” — Trial investigator/author, pediatric endocrinologist",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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