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  "documentTitle": "Soleno Therapeutics (SLNO)",
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      "text": "Trial was functionally unblinded due to hair growth and edema, as well as tablet smell; families were in touch via social media; impossible to blind",
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      "text": "A: “The hair thing is really difficult and same with the edema because you can't control for that. And you can't obviously give a placebo that would potentially make them have increased hair growth. It's difficult with this kind of study because you'll never be able to blind that properly.”\nQ: “Were you able to tell who was on drug, or were the patients able to tell who's on drugs because of these side effects or the smell?”\nA: “The smell was mentioned by one of them. The other, they were both males, they had a bit of hair growth...most of the patients in our group are on social media and the family forums and stuff.”\nQ: “Were you able to correctly guess which patients were on drug and placebo, like later on in the trial when it was officially unblinded? Was your guess correct?”\nA: “For one of them, yes. And it was kind of the distribution of the hair that he was growing that made us suspect it probably was.” - Trial investigator, pediatric endocrinologist",
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      "text": "“The hair thing is really difficult and same with the edema because you can't control for that. And you can't obviously give a placebo that would potentially make them have increased hair growth. It's difficult with this kind of study because you'll never be able to blind that properly.” — Trial investigator, pediatric endocrinologist",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "Trial investigator #6 stated that the trial was functionally unblinded due to hair growth and edema, making it easy to deduce who was on drug, and because Vykat tablets smelled differently than the placebo, which families figured out: “the hair things is really difficult and same with the edema...you’ll never be able to blind that properly”; “the smell was mentioned by one of them...patients in our group are on social media and the family forums and stuff.”",
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