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      "text": "the drug and the disease are not compatible, so don’t try it based on the physiology of the drug and the lack of that physiology that works normally in the patient.",
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      "text": "Stated that a quarter of PWS patients have a genetic subtype incompatible with Vykat due to potassium/magnesium regulation and the potential for cardiac and brain issues, as well as impact on the blood and lymphatic system.",
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      "text": "in 1 in 4, we think the biology is going to not be compatible with this drug because of the potassium issue...magnesium is disturbed in those 1 in 4...it can cause issues with muscle contraction., brain function...interferes with brain membranes...could be toxic to the brain.",
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      "text": "“the drug and the disease are not compatible, so don’t try it based on the physiology of the drug and the lack of that physiology that works normally in the patient.” — Trial investigator and physician; one of the leading KOL’s in the PWS field",
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      "text": "Trial investigator #1: Vykat’s mechanism of action is fundamentally incompatible with PWS patient physiology from a safety standpoint",
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