{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 276, "pageCount": 415, "prevPage": 275, "nextPage": 277, "slideType": "expose_contradiction", "function": "expose_contradiction", "density": "dense", "nDataPoints": 0, "notes": "The slide uses a Q&A format to highlight the tension between corporate marketing pressure and scientific/ethical boundaries.", "elementsJson": [ "paragraph", "quote_block" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/276", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-276", "components": [ { "bbox": null, "kind": "callout", "text": "I hear that there's been some pushing, but then when we've had our boundary, they've been respectful.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2ad-7e8036933687", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.86, "x": 0.07, "y": 0.23 }, "kind": "paragraph", "text": "Key PWS association implies “pushing” by Soleno for messaging that the association is uncomfortable with regarding Vykat", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6b58b2a6-feb5-46f4-8f5a-0219732868e0", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.35, "w": 0.86, "x": 0.07, "y": 0.27 }, "kind": "paragraph", "text": "A: “I would say people in my organization who, like the CEO or the executive director, those folks have more interaction with Soleno, although I certainly have had interactions. We have tried to be very mindful of not saying things that we would not feel good about saying. We really didn't want to lead the community astray. We are very loyal to the science. And have been really careful to be very honest with the community about what the findings are and the ways that it can help. We really wanted to make sure that there were certainly no one from our organization going out there saying this was a cure and everyone should be on it. We were very careful to say that's a decision for your family and to discuss with your physician. Like we've tried to hold the line in that regard. And my sense is — I hear that there's been some pushing, but then when we've had our boundary, they've been respectful.”\nQ: “What did they try to push on?”\nA: “Maybe wanting us to say something a little more strongly than we want than we felt comfortable saying from the science perspective.”\nQ: “What were you guys planning to say? And what do they ask you to say before backing off?”\nA: “I think we shared that it was really important that our representatives don't come out and say that this is a cure, or that there are no side effects or that everyone should be on it. But rather, here's the findings. This is a decision you need to make. We want to share the information with you and to talk with your doctors about it.”– Longtime researcher involved in PWS clinical trials at one of the two key PWS associations", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "b2598f65-ddab-4b9b-b580-ec66fa1e0390", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“We have tried to be very mindful of not saying things that we would not feel good about saying...we really didn't want to lead the community astray”; “we've tried to hold the line in that regard...I hear that there's been some pushing, but then when we've had our boundary, they've been respectful”; “wanting us to say something a little more strongly than we want than we felt comfortable saying from the science perspective”; “we shared that it was really important that our representatives don't come out and say that this is a cure, or that there are no side effects or that everyone should be on it.” — Longtime researcher involved in PWS clinical trials at one of the two key PWS associations", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2ad-80dcabcaa813", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.3, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "f19e8936-7e6a-4555-a39b-309a147e296b", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.15, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "title", "text": "The association hinted at pressure from Soleno to represent Vykat’s efficacy and safety profile in a manner that made them uncomfortable, telegraphing a clear lack of enthusiasm from the associations that heavily influence treatment in the PWS space", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "630b122a-97c0-4fa6-9581-649adfab5f58", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }