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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses expert quotes to undermine the perceived market opportunity for Soleno.",
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      "text": "The researcher was diplomatic but clearly negative about Soleno’s opportunity, indicating that patient enthusiasm was modest at best, and that families are already discussing and are highly concerned about the drug’s side effects.",
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      "text": "Both PWS associations are in touch with families across the country and are a key barometer of patient enthusiasm for Vykat. We interviewed a leading clinician and researcher who works at one of the two key associations and has been involved with numerous clinical trials, and who talks “to about 100 families on a regular basis”; “a lot of families call more informally when they have questions...when I go to conferences, families always talk to me.” The researcher was diplomatic but clearly negative about Soleno’s opportunity, indicating that patient enthusiasm was modest at best, and that families are already discussing and are highly concerned about the drug’s side effects: “our community is pretty savvy for a general population...I was surprised in one of our recent town halls that we had with just parents who might be interested, at the really thoughtful questions about some of the potential side effects and how that might impact a variety of other medical issues that people with Prader-Willi have...people were asking really good questions.”",
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      "text": "PWS families are “pretty savvy”: asking “really thoughtful questions about some of the potential side effects”",
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      "text": "Leading PWS clinician and researcher is in regular contact with ~100 PWS families. “I also have a clinical practice...within my work in the foundation, I talked to lots of families...I would say I’ve talked to about 100 families on a regular basis.”",
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      "text": "“I also have a clinical practice...within my work in the foundation, I talked to lots of families. A lot of families call more informally when they have questions. I know a lot of families from being part of the world. And when I go to conferences, families always talk to me. I would say I’ve talked to about 100 families on a regular basis. Not frequently, but have a touchpoint email or conversation at a conference.” — Longtime researcher involved in PWS clinical trials at one of the two key PWS associations; “I think our community is pretty savvy for a general population...I was surprised in one of our recent town halls that we had with just parents who might be interested, at the really thoughtful questions about some of the potential side effects and how that might impact a variety of other medical issues that people with Prader-Willi have because they can be complicated medically. But I thought parents were asking really good questions.” — Longtime researcher involved in PWS clinical trials at one of the two key PWS associations",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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