{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 268, "pageCount": 415, "prevPage": 267, "nextPage": 269, "slideType": "expose_contradiction", "function": "expose_contradiction", "density": "dense", "nDataPoints": 0, "notes": "The slide uses a direct quote to highlight a conflict of interest or professional disagreement regarding medical standards.", "elementsJson": [ "paragraph", "quote_block" ], "metadataConfidence": 0.95, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/268", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-268", "components": [ { "bbox": null, "kind": "callout", "text": "Jennifer Miller “backdrop of this whole diazoxide thing”; allegedly promoting questionable supplements for PWS; patients may be highly influenced and ask for requests “that are a little bit maybe out there”", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2ae-5f51ffdfc38c", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.45, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "paragraph", "text": "A lead pediatric endocrinologist at an academic center, one of the largest PWS clinics in the US with 30-40 patients, expressed concern about Jennifer Miller’s role “in the backdrop of this whole diazoxide thing,” opining that she is highly influential with PWS families who “think that they're seeing the world's expert in PWS...” but that her interventions are questionable – “It's a very unique situation in the PWS community because Miller is a destination for these families... there's other interventions that are not evidence-based that she promotes...she promotes these things as really important...and so, patients will go see her, and come back and want to start these non-evidence-based supplements...she's a proponent of these loosely evidence-based interventions for Prader-Willi Syndrome...and I feel like patients come back with a lot of requests, oftentimes, that are a little bit maybe out there that they're asking me to co-sign....”", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "568ae49c-d79c-42f8-b0bf-05c4e3d61c2b", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.28, "w": 0.86, "x": 0.07, "y": 0.63 }, "kind": "quote", "text": "“It's a very unique situation in the PWS community because Miller is a destination for these families. As I've been taking care of these patients over the last ten years, there's other interventions that are not evidence-based that she promotes. She promotes these things as really important. And so, patients will go see her, and come back and want to start these non-evidence-based supplements. And some of it has some data, and it's all pretty benign and cheap, to be honest. So, a lot of us are pretty agnostic about these interventions that it's just like whatever. But she's a proponent of these loosely evidence-based interventions for Prader-Willi Syndrome. And I feel like patients come back with a lot of requests, oftentimes, that are a little bit maybe out there that they're asking me to co-sign as their doctor that they see throughout the year. And most of the time, I do because they're generally benign things that they're convinced are going to be helpful. And so, in the backdrop of this whole diazoxide thing.... some of my patients go see this doctor once a year, and they see me the other times of the year because they think that they're seeing the world's expert in PWS.” - Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6ef6c47a-517f-40c1-ac5b-549a6fe96a35", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.08, "w": 0.86, "x": 0.07, "y": 0.55 }, "kind": "quote", "text": "Jennifer Miller “backdrop of this whole diazoxide thing”; allegedly promoting questionable supplements for PWS; patients may be highly influenced and ask for requests “that are a little bit maybe out there”", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "d14b11cd-0628-4813-826f-8240b113dd68", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "It's a very unique situation in the PWS community because Miller is a destination for these families. As I've been taking care of these patients over the last ten years, there's other interventions that are not evidence-based that she promotes. She promotes these things as really important. And so, patients will go see her, and come back and want to start these non-evidence-based supplements. And some of it has some data, and it's all pretty benign and cheap, to be honest. So, a lot of us are pretty agnostic about these interventions that it's just like whatever. But she's a proponent of these loosely evidence-based interventions for Prader-Willi Syndrome. And I feel like patients come back with a lot of requests, oftentimes, that are a little bit maybe out there that they're asking me to co-sign as their doctor that they see throughout the year. And most of the time, I do because they're generally benign things that they're convinced are going to be helpful. And so, in the backdrop of this whole diazoxide thing.... some of my patients go see this doctor once a year, and they see me the other times of the year because they think that they're seeing the world's expert in PWS. — Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2ae-6096756aede0", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.3, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "30ccd2d9-4cbd-484b-b43e-96ef22c13a57", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "antagonist-introduction", "slug": null, "matchId": "675e7684-b40b-48f3-bcae-75030dd3e36d", "evidence": "The slide frames Jennifer Miller as an antagonist by citing a peer's critique of her professional practices.", "confidence": 0.8 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }