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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses direct quotes from a KOL to undermine the company's marketing narrative.",
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      "text": "Bombarding patients with “infomercials” and forums",
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      "text": "Vykat is not an option for diabetic or pre-diabetic patients; patients taking a “wait and see” attitude; “we don’t really know” side effects",
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      "text": "The reluctance, despite Soleno’s over-the-top bombardment of patients and prescribers, indicates significant challenges for Vykat",
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      "text": "The KOL cast doubt on the success of Vykat’s launch, indicating significant reluctance on the part of PWS families – we note that the KOL is a longtime, highly-networked, go-to resource for families around the country with a prominent profile in the PWS patient community. The KOL indicated families are already wary of Vykat’s diabetes risk, given 30-40% of PWS patients are diabetic and the rest are obese, pre-diabetic, and generally at extreme risk of developing the condition – “people with diabetes probably wouldn’t be an option...prediabetes, it wouldn’t be an option...you’re going to have a lot of people say, and I have had several people say...they’re going to kind of wait and see...that’s probably a pretty smart move, to be honest...” The reluctance, despite Soleno’s over-the-top bombardment of patients and prescribers, indicates significant challenges for Vykat – “I myself am getting emails from Soleno...they’re sending out lots of mass promotional things to try to get people to prescribe, for sure.”",
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      "text": "I will say that there’s several patient or parent forums that are getting —one family said, \"Oh, there’s a couple of forums.\" I’m like, \"Is Soleno running them?\" And they’re like, \"I don’t know.\" It’s interesting that people are not sure where the data is coming from or where the information is coming from. I myself am getting emails from Soleno, so they’re sending out lots of mass kinds of promotional things to try to get people to prescribe, for sure...there was a big —.",
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      "text": "People with diabetes probably wouldn’t be an option. For people in prediabetes, it wouldn’t be an option. So I think you’re going to have a lot of people say, and I have had several people say, I’m going to kind of wait till it’s been out for a little bit longer so that I can kind of like, determine for myself whether this would be something that I could do. I think for some people, that’s kind of the thing is they’re going to kind of wait and see. I think that’s probably a pretty smart move, to be honest with you, because we don’t really know.",
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      "text": "People with diabetes probably wouldn't be an option. For people in prediabetes, it wouldn't be an option. So I think you're going to have a lot of people say, and I have had several people say, I'm going to kind of wait till it's been out for a little bit longer so that I can kind of like, determine for myself whether this would be something that I could do. I think for some people, that's kind of the thing they're going to kind of wait and see. I think that's probably a pretty smart move, to be honest with you, because we don't really know. — KOL in the PWS field; involved with Soleno's clinical program",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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