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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses direct quotes to build a case of corporate malfeasance regarding safety disclosures.",
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      "kind": "callout",
      "text": "Soleno is allegedly obfuscating that the mechanism of action inherently creates diabetes risk",
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      "text": "Side effect risk is being downplayed and minimized",
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      "text": "Soleno is willfully playing dumb – “the side effects just really feel like they’re being minimized...every call I’ve been on...they’re not really talking much about it...they’re really minimizing the fact that this drug does have some serious side effects”.",
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      "text": "“the side effects just really feel like they’re being minimized...every call I’ve been on...they’re not really talking much about it...they’re really minimizing the fact that this drug does have some serious side effects”; “they keep saying they don’t definitively know how it works...what do you mean you don’t know how it works?....it suppresses insulin secretion from the pancreas...even I understand that...we do know how it works...it increases blood sugar...for people who might get diabetes, that would concern me...when I told the mom...that mechanism of action...she goes, oh, I didn’t know that...so much of this is not being brought to people people’s attention.”",
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      "text": "“They keep saying they don’t definitely know how it works. What do you mean you don’t know how it works? It suppresses insulin secretion from the pancreas. Even I understand that. When they say, well, they’re not exactly sure how it works. I think we do know how it works. It increases blood sugar in the bloodstream. And again, for people who might get diabetes, that would concern me. When I told the mom that, I said that mechanism of action is this. And she goes, oh, I didn’t know that. I’m like, I know. So much of this is not being brought to people’s attention.” – KOL in the PWS field; involved with Soleno’s clinical program",
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      "text": "“I definitely think there’s some issues. If you’re talking to investigators — if they see a lot of people, I totally would trust their judgment when it comes to what they would recommend and what they wouldn’t. And I do find that the side effects just really feel like they’re being minimized. And every call I’ve been on for anything, they’re not really talking much about it — they’re saying for people to be on a healthy diet and exercise, and I’m in my head going, well, that’s their problem. It feels like they’re really minimizing the fact that this drug does have some serious side effects.” – KOL in the PWS field; involved with Soleno’s clinical program",
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      "text": "“I definitely think there's some issues. If you're talking to investigators — if they see a lot of people, I totally would trust their judgment when it comes to what they would recommend and what they wouldn't. And I do find that the side effects just really feel like they're being minimized. And every call I've been on for anything, they're not really talking much about it — they're saying for people to be on a healthy diet and exercise, and I'm in my head going, well, that's their problem. It feels like they're really minimizing the fact that this drug does have some serious side effects.” — KOL in the PWS field; involved with Soleno's clinical program",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "The KOL repeatedly alluded to a cover-up of serious, potentially fatal risks, stating that they are inherent to Vykat’s mechanism of action and alleging that Soleno is willfully playing dumb",
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