{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 226, "pageCount": 415, "prevPage": 225, "nextPage": 227, "slideType": "expose_contradiction", "function": "expose_contradiction", "density": "dense", "nDataPoints": 0, "notes": "The slide uses direct quotes from an ex-employee to build a case of corporate misconduct regarding clinical trial data.", "elementsJson": [ "paragraph", "quote_block" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/226", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-226", "components": [ { "bbox": null, "kind": "callout", "text": "in general, the company did downplay the diabetes risk and also downplay some of the serious adverse events that were reported.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2a8-d45d71f1977b", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.08, "w": 0.86, "x": 0.07, "y": 0.84 }, "kind": "list", "text": "“Pressure” on investigators to downplay adverse effects\n“There was certainly some pressure on all the investigators to downplay the adverse effects.” – Ex-Soleno employee #1, key role in clinical trial program", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "32ca877c-d01a-4661-9527-62fdce481862", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.12, "w": 0.86, "x": 0.07, "y": 0.45 }, "kind": "list", "text": "Company allegedly tried to “downplay the diabetes risk” and “serious adverse events”; individuals allegedly let go for pushing back\n“in general, the company did downplay the diabetes risk and also downplay some of the serious adverse events that were reported.” – Ex-Soleno employee #1, key role in clinical trial program", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "3531a492-3bfb-4fd6-b0a4-77c1d02bdf95", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.25, "w": 0.86, "x": 0.07, "y": 0.58 }, "kind": "list", "text": "“Extremely uncomfortable” at alleged direction to downplay safety risks\nQ: “One of the authors of a paper told me they were getting pressure from the company to downplay safety data, and that they were then not listed as an author in subsequent trials. That tells me that the company is looking to solve for a particular outcome.”\nA: “Yes, and your read is absolutely right. I was extremely uncomfortable with the direction from [redacted] to try and downplay things.”\nQ: “You mean safety data?”\nA: “It’s not what I would do. It’s not what most normal companies would do. But they’ve been working on this for a very long time. And they wanted a successful outcome. And I think all the people with significant financial incentive were the ones driving this train.” – Ex-Soleno employee #1, key role in clinical trial program", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "4606bbbc-2e7b-4ad3-88f3-93ecfd341344", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.35, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "paragraph", "text": "The ex-employee expressed concern that Soleno has downplayed the risk of serious adverse effects; and “was extremely uncomfortable” at alleged pressure to downplay the safety risks – on both employees and investigators – “certainly some pressure on all the investigators to downplay the adverse effects”; “I was extremely uncomfortable with the direction from [redacted] to try and downplay things…it’s not what I would do…it’s not what most normal companies would do…they wanted a successful outcome…all the people with significant incentive were the ones driving this train”; “the company did downplay the diabetes risk and also downplay some of the serious adverse events that were reported…”", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "46981b57-b3a3-439b-b867-52d0ce86cc4b", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“in general, the company did downplay the diabetes risk and also downplay some of the serious adverse events that were reported.” — Ex-Soleno employee #1, key role in clinical trial program", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2a8-d93edbbae0b5", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.25, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "e8067227-dbca-4396-9aad-2dea77e1e23b", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "fraud-exposure", "slug": null, "matchId": "d4eee1f8-e949-4843-8844-afc7dc007094", "evidence": "The slide systematically presents testimonial evidence to allege corporate fraud and data manipulation.", "confidence": 0.9 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }