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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses annotated charts to highlight alleged data manipulation in a clinical study.",
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      "text": "The oral suspension curve is oddly pointy and the DCCR curve is flat with identical concentrations over 12 hours",
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      "text": "Figure 1. Plasma concentration 0-120 hours in clinical study PK001",
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      "text": "The DCCR curve is flat with identical drug concentrations encompassing 6 timepoints over a 12-hour plateau. The half-life for DCCR throughout the poster is ~30 h. The elimination phase oddly spans Tmax to 96 h as a straight line. Lack of other publicly available DCCR data.",
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      "text": "The blue curve shows DCCR plasma concentration, and is flat with identical drug concentrations over 6 timepoints over a 12-hour plateau – a fantasy that strains credibility, suggesting to us that the authors just chopped off the top of the blue curve to make it look less spiky than oral suspension - sloppy 7th grade-level data games.",
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      "text": "Source: https://abstracts.eurospe.org/hrp/0089/eposters/hrp0089lb-p8_eposter.pdf; Scorpion Capital analysis and estimates",
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      "text": "The key PK chart that underpins Soleno’s entire existence reeks of data irregularities.",
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