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  "docSlug": "f06b0b5d2079",
  "documentTitle": "Soleno Therapeutics (SLNO)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses a 'before-after' or 'comparison' logic to undermine the pricing power of the target company (Vykat) by highlighting readily available, cheaper alternatives.",
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      "text": "Regular diazoxide whether generic or Proglycem is radically cheaper than Vykat’s $500K to $1MM+ annual cost, given its weight-based pricing – likely cheaper than the Vykat co-pay for those able to get insurance approval.",
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      "text": "Canadian online pharmacy screenshot",
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      "text": "annual cost: $500K",
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      "text": "Vykat’s titration table indicates a maintenance dose of ~4mg/kg, which at the average weight of ~60kg in the phase 3 implies 240mg/day. Dozens of online Canadian pharmacies will ship a Proglycem 100-capsule 100mg box to the US for $270, implying a daily cost of $6.48, which is $190/mo or $2,365/year. US compounding pharmacies also sell diazoxide in custom capsule dosages and ship across state lines, as countless KPI suppliers sell inexpensive bulk diazoxide powder, in addition to compounding various versions of the suspension. A global API supplier site lists 32 API suppliers for diazoxide powder, with 17 in India alone.",
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      "text": "Source: https://www.canadianpharmacyworld.com/brand/Proglycem/100+mg; https://www.bayviewrx.com/formulas/Diazoxide-50-mg-Oral-Capsules-Hypoglycemia-Insulinoma-Congenital-Hyperinsulinism-Hyperinsulinism-Hypertension; https://www.chemicalbook.com/manufacturers-india/diazoxide.htm",
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      "text": "Regular diazoxide whether generic or Proglycem is radically cheaper than Vykat’s $500K to $1MM+ annual cost, given its weight-based pricing – likely cheaper than the Vykat co-pay for those able to get insurance approval.",
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