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      "text": "Growth hormone + Vykat magnifies risk; diabetic ketoacidosis – \"we've had a couple of deaths from DKA\" ... \"The other thing you have to realize is if you got somebody on diazoxide and you've got somebody on growth hormone...\"",
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      "text": "It's a two-hit. It's two hits. That increases your risk. Absolutely.",
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      "text": "Combination of growth hormone and Vykat escalates diabetes risk - DKA and hyperosmolar with risk of fatal outcomes. Q&A transcript follows.",
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      "text": "As an example, we quote the Division Chief for pediatric endocrinology at a major academic center who treats 20 PWS patients – \"it's a two-hit...that increases your risk...absolutely\"- citing multiple fatalities he has seen from DKA, coma, and hyperosmolar...",
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      "text": "\"if you got somebody on diazoxide and you've got somebody on growth hormone... that also is increasing your risk of diabetes...in DKA in overweight people, you also can get type 2 diabetes and wind up in a different type of ketoacidosis with hyperosmolar problems and coma...we've had a couple of deaths from DKA, but we've actually had two from hyperosmolar, type 2's...you're on a second medication that is increasing your sugar while you're on a medication that may be decreasing your insulin...and if you get DKA in type 2, there's a subset that gets something called hyperosmolar...it's bad and very, very difficult to treat...it has a relatively high mortality rate....\" — Pediatric endocrinologist, division chief at an academic center",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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