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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses a line chart with error bars to argue that the mean value hides adverse patient outcomes. It highlights the 1-standard deviation range and extrapolates to 2-standard deviations.",
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      "text": "The blue error bars on Soleno’s HbA1c chart are the key to understanding the clear evidence of T2D risk – which is obfuscated by the green line (mean).",
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      "text": "Hemoglobin A1C: 6.4%",
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      "text": "The blue error bars on Soleno's HbA1c chart are the key to understanding the clear evidence of T2D risk – which is obfuscated by the green line (mean). The blue bars are one standard deviation, which means they encompass 68% of the population. Note that the error bars expand over time, particularly at week 13, and cross the threshold for prediabetes (>5.7%) and eventually T2D (>6.4%) as shown in the two dotted red lines that we overlay. However, the blue bars are only one standard deviation (68%) – two standard deviations (encompassing 95% of the population) would show a significant percentage of patients crossing the threshold for T2D as well – which we shortly calculate.",
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      "kind": "quote",
      "text": "May 16, 2024 poster by Gevers, Miller et al – Soleno website",
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      "text": "Source: https://investors.soleno.life/static-files/27318113-e299-408f-ba14-0b05114f37bc",
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      "text": "FIGURE 1: Mean Hemoglobin A1C (%) by Week of DCCR Administration",
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