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  "documentTitle": "Soleno Therapeutics (SLNO)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
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  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2025-08-15 00:00:00",
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  "pageNumber": 114,
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  "slideType": "expose_contradiction",
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  "density": "dense",
  "nDataPoints": 9,
  "notes": "The red box highlights the specific data point (Week 0 to Week 13) where the pooling occurs.",
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      "text": "Close observation of the chart indicates the claim is dubious. As an initial red flag, the mean hbA1c at week 13 – the end of the Phase 3 double-blind portion – is shown only as pooled average mixed population.",
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      "kind": "chart",
      "text": "Mean Hemoglobin A1C (%) by Week of DCCR Administration",
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      "text": "HbA1c",
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      "kind": "paragraph",
      "text": "We excerpt the HbA1c graph below – the data at the heart of Soleno’s diabetes-related obfuscation. The poster has almost no discussion of this critical chart, glossing over it with one sentence: “Longitudinal mean fasting glucose (FG) and HbA1c increased slightly over the initial 6-9 months but stabilized or returned to near-baseline levels upon continued DCCR dosing (Figure 1 and Figure 2).” Close observation of the chart indicates the claim is dubious. As an initial red flag, the mean hbA1c at week 13 – the end of the Phase 3 double-blind portion – is shown only as pooled average mixed population. That is, it averages the drug and placebo arms instead of showing separated hbA1c values for each group.",
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      "kind": "quote",
      "text": "Longitudinal mean fasting glucose (FG) and HbA1c increased slightly over the initial 6-9 months but stabilized or returned to near-baseline levels upon continued DCCR dosing (Figure 1 and Figure 2). — May 16, 2024 poster by Gevers, Miller et al",
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      "text": "Source: https://investors.soleno.life/static-files/27318113-e299-408f-ba14-0b05114f37bc",
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      "text": "May 16, 2024 poster by Gevers, Miller et al – Soleno website",
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