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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses direct quotes to expose contradictions in the drug's adoption and safety profile.",
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      "text": "He indicated little interest in prescribing the drug unless a patient pushes for it, and that despite the one Vykat start form submitted, physicians may \"try it once or twice\" and quickly move on or prescribe generic diazoxide suspension off-label versus chasing insurers.",
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      "text": "His PWS group has submitted only one Vykat start form which remains unapproved. Indicated no discussion or buzz about Vykat among endocrinologists. Provided alarming color about Vykat's potential to cause edema and proteinuria. Little interest in prescribing.",
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      "text": "\"I haven't gotten approved...we have filled out the form...oh yeah, it's taking time.\" — PWS nephrologist #11; \"there were a few patients that were already on Vykat that were referred for edema and proteinuria\"; \"we weren't sure if it was a side effect of the drug, but that was the presumed mechanism\"; \"yes...for sure.\" — PWS nephrologist #11 regarding unblinding.",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "PWS nephrologist #11: Manages 5 to 7 PWS patients in conjunction with endocrinologists at a large community care system in a major metropolitan area, mainly for edema and electrolyte imbalances like acidosis-alkalosis prevalent in the disease state.",
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