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  "documentTitle": "Nevro Corp. (NVRO)",
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  "authorName": "Kir Kahlon",
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      "text": "Numerous KOL's pointed to tolerization as a reason for high frequency's failure, suggesting that Nevro's device overwhelms the spinal cord with current, which backfires by resulting in a faster adaptive response than traditional stimulators.",
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      "text": "Numerous KOL's pointed to tolerization as a reason for high frequency's failure, suggesting that Nevro's device overwhelms the spinal cord with current, which backfires by resulting in a faster adaptive response than traditional stimulators.",
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      "text": "I've observed, when I and other doctors get together and talk about this, that patients tune out of high frequency faster than traditional stimulators. In one year the devices are all the same and the curves converge. There's no difference in efficacy.",
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      "text": "People get used to high frequency. My hypothesis is that the neurons may re-learn and then the pain can come back.",
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      "text": "You can only beat on the spinal cord so long before a refractory response happens. Look at drugs – ones that effect the nervous system lead to tolerance. I'm saying it's just too much energy and you have to back off.",
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      "text": "\"People get used to high frequency. My hypothesis is that the neurons may re-learn and then the pain can come back.\" — KOL in Europe; \"I've observed, when I and other doctors get together and talk about this, that patients tune out of high frequency faster than traditional stimulators. In one year the devices are all the same and the curves converge. There's no difference in efficacy. Maybe a little bit on the front end but it disappears by 12 months.\" — High volume implanter/KOL and Nevro user; \"You can only beat on the spinal cord so long before a refractory response happens. Look at drugs – ones that effect the nervous system lead to tolerance. I'm saying it's just too much energy and you have to back off. Either the cells are down-regulating and can't hear the noise anymore, or there's an inflammatory response to high frequency and you get cell formation that's impeding the electrical signal.\" — KOL and former high volume Nevro implanter",
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      "text": "4. HF10 is a phony premise and mechanism of action",
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      "text": "Scorpion Capital | Nevro (NYSE: NVRO)",
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