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  "notes": "The slide uses expert testimony to establish a precedent of failure in the H3 receptor space, specifically contrasting J&J's robust trials with Bioprojet's pitolisant.",
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      "text": "He stated that they conducted “very robust trials” after screening countless compounds, across many indications such as narcolepsy – and that all of these efforts were failures.",
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      "text": "One of the most informative scientists we consulted spent decades at Johnson & Johnson/Janssen in senior neuroscience and other roles, with hundreds of published papers and patents to his credit.",
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      "text": "We were the folks that actually cloned the human H3 receptor... it was relatively easy to find lead compounds... We began the program in 1999.",
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      "text": "They were very robust trials... the decision was not to move forward... we looked at excessive daytime sleepiness in narcoleptics, and we compared it to modafinil, which is what Schwartz did as well.",
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      "text": "“We were the folks that actually cloned the human H3 receptor, and that's public domain, and we began with a high throughput screen. We ended up with a bunch of really good compounds, and once we published that stuff, every other company jumped on.” — Longtime senior scientist at Johnson & Johnson, with global leadership roles in neuroscience",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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