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      "text": "Of the two histamine receptor antagonists that were recalled, one was terfenadine which is now infamous as the poster child for fatal QT prolongation.",
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      "text": "Of the two histamine receptor antagonists that were recalled, one was terfenadine which is now infamous as the poster child for fatal QT prolongation. It was introduced as Seldane in the US in 1985, the first prescription antihistamine for allergies. In 1990, the FDA issued a report on serious ventricular arrythmias and forced the company to send an alert to all physicians. A black box warning followed in 1992, the same time that it was discovered to have liver as well as cardiac toxicity, culminating with the FDA forcing the drug off the market in 1997.",
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      "text": "Source: https://www.nytimes.com/1997/01/17/opinion/the-hazards-of-seldane.html...; https://www.washingtonpost.com/archive/politics/1997/01/14/fda-wants-drug-seldane-off-market/8f7d42b9-2e91-42fd-9576-49882c60f600/...",
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