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  "documentTitle": "Harmony Biosciences (HRMY)",
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  "notes": "The slide uses a Q&A format to validate the thesis that high-volume prescribers quickly exhaust their patient pool and face insurance hurdles, contradicting potential growth narratives.",
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      "text": "Whale prescribers cutting prescriptions as they run out of patients or have no clinical results or “heat” from insurers",
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      "text": "They described a predictable pattern - an initial flurry of interest for a new drug followed by reality within two years, as the few doctors willing to try it ran out of patients or soured due to lack of clinical efficacy.",
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      "text": "Whale prescribers cutting prescriptions as they run out of patients or have no clinical results or “heat” from insurers",
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      "text": "Q: “How many Wakix scripts did he [the only whale prescriber in the territory] write, or how many patients did he have on at a time roughly? And does he still use it? Are you still in touch with him?”\nA: “That launch year, I think he had like 12 patients. So, I think he had like four a quarter. And when we launched, the message was we’ll get your patients that are on medication that are not doing well. So, I think he had 12 the first year, and he had much less the second year because a lot of doctors when a new drug comes out, they’re looking for patients, and then they get through their patient deck, and they’re like, I don’t have any more patients. I’ve tried it on everybody. It was definitely less.”\nQ: “You said he had about 12 the first year. How many did he have the second year?”\nA: “In June, when we launched, he had a couple, and then he picked—I’m going off memory—and then he tapered back. I think he was getting a lot of heat from the insurance company right there at the end of 2020, end of 2021, and he scaled back quite a bit. He was going with about four patients a month, and this is average, just depending. And then it dropped off there at the end when I was leaving there. I think he was getting some pushback, probably from the insurance companies. I don’t think he was seeing the results that he wanted to see from these patients the had put on it.” – Ex-Harmony territory manager for a large southeast region across two states",
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      "text": "A third ex-territory manager detailed what occurred in his region. A high volume prescriber who carried his territory – a “whale” and of course a speaker – put as many patients onto Wakix as he could the first year, but “he had much less the second year...they get through their patient deck and they’re like, I don’t have any more patients...I tried it on everybody.” The rep stated that this whale was “getting a lot of heat from the insurance company” and wasn’t “seeing the results that he wanted to see from...patients he had put on it.”",
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      "text": "“I don't have any more patients. I've tried it on everybody.” — Ex-Harmony territory manager for a large southeast region across two states",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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