{
  "docId": "019dd923-622c-750b-8b9a-21918ac10c17",
  "docSlug": "f3db2294dcf9",
  "documentTitle": "Harmony Biosciences (HRMY)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
  "documentKindSlug": "research-note",
  "documentKindLabel": "Research note",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2023-03-28 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.3333334,
  "pageNumber": 31,
  "pageCount": 366,
  "prevPage": 30,
  "nextPage": 32,
  "slideType": "expose_contradiction",
  "function": "expose_contradiction",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "The slide argues that the patent claims are spurious because the inventors are the same as those who published the molecule in 2002, and PubChem shows prior art from 2006.",
  "elementsJson": [
    "paragraph",
    "screenshot"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b9a-21918ac10c17/31",
  "deckHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17#slide-31",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "The lawyer indicated the tactic is spurious and that an IPR would be prejudicial against the company, as it establishes an attempt to mislead the patent office.",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-64d0-7099-9ccb-07cccf23b3df",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.42,
        "x": 0.52,
        "y": 0.66
      },
      "kind": "image",
      "text": "PubChem entry for Pitolisant Hydrochloride",
      "attrs": null,
      "subkind": "screenshot",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8b999b5f-9bac-40c4-a39c-5933f37e3e2a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.42,
        "x": 0.07,
        "y": 0.67
      },
      "kind": "image",
      "text": "Patent snippet showing inventors list",
      "attrs": null,
      "subkind": "screenshot",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8c6907c1-2254-4596-bdc3-e2b0e576077c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.52,
        "w": 0.86,
        "x": 0.07,
        "y": 0.07
      },
      "kind": "paragraph",
      "text": "Harmony has no intellectual property, which is besides the point as no reputable pharma company would market a drug this toxic and risk existential tort litigation, but at the very least it removes any possibility of acquisition – already remote as the 3 US patents expire in 3, 6, and 7 years, respectively. We nonetheless asked a biotech IP litigator – someone with decades of experience and who we have consulted for years – to review each US patent. Bioprojet knew that their prior publication of the molecule’s structure would be problematic, and hence asserted in the US patents that they had invented a novel salt of the molecule – pitolisant hydrochloride – and that the previous molecule was merely a base. The lawyer indicated the tactic is spurious and that an IPR would be prejudicial against the company, as it establishes an attempt to mislead the patent office. He stated it is damning that the authors on the US patents are the same as the ones in the 2002 paper; and that even then, PubChem shows the patented salt published as prior art in 2006, and perhaps earlier if one commissions a search from the American Chemical Society’s database.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ca77a517-49c7-4554-aa14-c7792dff3a8e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.75,
        "x": 0.07,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Source: https://patentimages.storage.googleapis.com/ca/f6/6a/aa89c81f61fd29/US8207197.pdf; https://pubchem.ncbi.nlm.nih.gov/#query=pitolisant%20hydrochloride",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "112aab51-a03e-4c6a-a9ee-b92ca22bedec",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.42,
        "x": 0.07,
        "y": 0.61
      },
      "kind": "title",
      "text": "Inventors listed on patents are the authors of 2002 paper",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "fe28660d-19ed-483b-b01e-45370d23bd3e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.42,
        "x": 0.52,
        "y": 0.61
      },
      "kind": "title",
      "text": "PubChem shows 2006 prior art for the HCL salt",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "fff3f5f1-7d3c-4073-8635-034e01c5097f",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [
    {
      "name": "fraud-exposure",
      "slug": null,
      "matchId": "4405039a-0499-46a1-aee4-05eed5fa7063",
      "evidence": "The slide explicitly details an attempt to mislead the patent office and identifies prior art.",
      "confidence": 0.9
    }
  ],
  "arcBeats": [
    {
      "to": 50,
      "from": 31,
      "beatId": "2b789ae4-940c-4d3a-9f03-7f2e7e4f46fd",
      "arcName": "Overcoming the Monster",
      "arcSlug": "overcoming-monster",
      "beatName": "The Struggle",
      "beatSlug": null,
      "evidence": "The document presents the struggle of the company's critics and short-sellers to expose the truth",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": null,
      "parentBeatSlug": null
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}