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  "documentTitle": "Harmony Biosciences (HRMY)",
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  "notes": "The slide contrasts the prescriber's relaxed attitude toward cardiac/hepatic monitoring with a specific, concerning anecdote about a patient experiencing uncontrollable anger.",
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      "text": "She doesn't have any psychosis or bipolar or anything that would say we can just write this off as the fact that she's had psychiatric illness.",
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      "text": "No cardiac screening; no cardiac risk; no hepatic risk; only run one EKG; complacent",
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      "text": "Troubling psychiatric side effect in a patient with no existing history, started within 1-2 weeks",
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      "text": "But with Wakix, it doesn't really have any significant signal... I've only run an EKG on one such patient... I think that's not monitored routinely in narcolepsy centers... I think that's something that we're going to have to watch.",
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      "text": "Q: What's the worst side effect you've ever had? A: ...a woman who went on Wakix... she had uncontrollable bursts of anger... Within the first, either week one or week two... She doesn't have any psychosis or bipolar...",
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      "text": "“But with Wakix, it doesn't really have any significant signal in terms of changing blood pressure or heart rate. I've been very comfortable adding it right on top. So, that's actually been very useful as well... I've only run an EKG on one such patient because of that..the QT prolongation, I don't think, is something that clinicians are particularly concerned about if they're familiar with QT prolongation.” — Neurologist in Texas, one of largest sleep practices in the US",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "Prescriber #11: Neurologist in Texas with “one of the largest narcolepsy patient populations in the US” 200 narcolepsy patients total, of which 50 are on Wakix. Has a long history with Harmony, serving as a key trial investigator, adviser, and speaker.",
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