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  "documentTitle": "Harmony Biosciences (HRMY)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2023-03-28 00:00:00",
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      "text": "Our doctor interviews indicate no shortage of options.",
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      "text": "First, narcolepsy is ultra-rare at 0.04% of the US population and cataplexy is rarer still at 0.005% - in other words, only ~10% of narcoleptics have it. Cataplexy is vaguely defined as “sudden and transient episodes of loss of motor tone triggered by emotions.” Narcoleptics are not collapsing on the street like cataplectic goats when tickled, as attacks are brief at seconds or minutes, “self-limiting and resolve without medical attention,” often barely perceptible such as a twitch of an eyebrow, and the symptom is well-handled with SSRI’s. Second, the market for EDS - Wakix’s only other market opportunity besides cataplexy - is crowded with numerous approved drugs, such as amphetamines (Adderall), methylphenidates (Ritalin), modafinil and its variants, antidepressants like SSRI’s, sodium oxybate’s like Jazz Pharma’s Xyrem and Xywav, and solriamfetol (Sunosi). Our doctor interviews indicate no shortage of options.",
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      "text": "Source: http://www.sleepscience.org.br/details/401/en-US/current-and-future-treatment-options-for-narcolepsy--a-review",
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