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  "documentTitle": "Harmony Biosciences (HRMY)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2023-03-28 00:00:00",
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  "notes": "The slide uses a table of clinical trials alongside red-text annotations to highlight the geographic and temporal distance of the studies.",
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      "text": "The Bioprojet/Harmony trials are not credible scientific studies, but rather dishonest attempts to manipulate trial design and data in order to achieve a predetermined outcome",
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      "text": "Harmony 3 conducted from May 2011 to Oct 2013, in France and Hungary",
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      "text": "Harmony 1-bis conducted from Oct 2010 to Jul 2012, in Argentina, Hungary, France, Italy, Spain, Finland, Austria, and Germany",
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      "text": "Harmony investor presentation, Nov 2022",
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      "text": "Source: https://ir.harmonybiosciences.com/static-files/f5315c60-3f1e-4207-aa4f-53bff52dbe54",
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      "text": "The Bioprojet/Harmony trials are not credible scientific studies, but rather dishonest attempts to manipulate trial design and data in order to achieve a predetermined outcome and/or drag the results across the finish line, making a mockery of the scientific method, and highlight the abuses as companies like Harmony and their consultants manipulate and game the extraordinary deference the FDA grants applicants under its accelerated approval pathways. We shall go through each trial in turn and illustrate red flags, statistical tricks, and omissions so rampant that the entire exercise - in our opinion - may be considered a scientific fraud. We first note that although the FDA approved the drug in 2019, the trials are ancient and conducted only in foreign jurisdictions – the typical Jeff Aronin playbook which focuses on old, toxic drugs one else would touch.",
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