{
  "docId": "019dd923-622c-750b-8b9a-21918ac10c17",
  "docSlug": "f3db2294dcf9",
  "documentTitle": "Harmony Biosciences (HRMY)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
  "documentKindSlug": "research-note",
  "documentKindLabel": "Research note",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2023-03-28 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.3333334,
  "pageNumber": 198,
  "pageCount": 366,
  "prevPage": 197,
  "nextPage": 199,
  "slideType": "other",
  "function": "illustrate_case",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "This appears to be a medical case report document from the FDA FAERS database.",
  "elementsJson": [
    "paragraph",
    "screenshot",
    "footnote"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b9a-21918ac10c17/198",
  "deckHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-21918ac10c17#slide-198",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "As hypersensitivity, including anaphylactic reaction, is a known risk associated with WAKIX, a causal or contributory role of WAKIX cannot be ruled out.",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-64d1-73a9-abb5-3e2ee185a08c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.09,
        "x": 0.12,
        "y": 0.71
      },
      "kind": "image",
      "text": "FDA",
      "attrs": null,
      "subkind": "logo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "2c9ddd0e-1e25-4712-927c-3ca3ce83963c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.86,
        "x": 0.07,
        "y": 0.43
      },
      "kind": "paragraph",
      "text": "Event/Problem Narrative: On 23-APR-2021, a spontaneous report was received from a physician via a company representative regarding a female who was being treated with WAKIX (pitolisant) and an unspecified allergy skin test...",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "368186d6-369c-413b-8fd1-94532ce86040",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.18,
        "w": 0.86,
        "x": 0.07,
        "y": 0.11
      },
      "kind": "paragraph",
      "text": "A female patient of an unknown age and on an unknown dose of pitolisant underwent an allergy skin test consisting of injections in a grid-like pattern on her back and arm. While the skin test was being performed, the patient experienced an anaphylactic reaction that required two EpiPens (epinephrine injections). “The reporting physician noted the reaction was uncharacteristic of allergy skin testing and implicated WAKIX due to its histaminergic activity. As hypersensitivity, including anaphylactic reaction, is a known risk associated with WAKIX, a causal or contributory role of WAKIX cannot be ruled out.”",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e2b2b6c7-b2c2-4d8d-abfc-c70c97106a2b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "The reporting physician noted the reaction was uncharacteristic of allergy skin testing and implicated WAKIX due to its histaminergic activity. As hypersensitivity, including anaphylactic reaction, is a known risk associated with WAKIX, a causal or contributory role of WAKIX cannot be ruled out. — FDA Adverse Event Reporting System (FAERS) FOIA Case Report",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd953-64d1-73a9-abb5-40f641638760",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.02,
        "w": 0.3,
        "x": 0.07,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Source: FDA FAERS – FOIA Case Report Information",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "216da8b7-3ae4-4062-9b75-4deab4b2ee19",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.45,
        "x": 0.07,
        "y": 0.07
      },
      "kind": "title",
      "text": "Case ID: 19382701, Event date: 2021",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8f91c726-8184-4967-99a5-66eea65debc3",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.32,
        "x": 0.34,
        "y": 0.71
      },
      "kind": "title",
      "text": "FDA - Adverse Event Reporting System (FAERS) FOIA Case Report Information",
      "attrs": null,
      "subkind": "subtitle",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "846fef94-9bcd-43d9-8e44-0a4bc09e22e2",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}