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  "documentTitle": "Harmony Biosciences (HRMY)",
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      "text": "We note the similarity of the narrative to those in the fatalities table for pitolisant trials, where pulmonary involvement is prevalent.",
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      "text": "While reviewing papers on drug-induced phospholipidosis, we were struck by one that explained “the seriousness of DIPL” - “the results can be deadly” - by using a case study of a 62-year old woman who was admitted to a hospital “with difficulty breathing.” The condition was incorrectly assessed as bronchitis but was found to be drug-induced. We note the similarity of the narrative to those in the fatalities table for pitolisant trials, where pulmonary involvement is prevalent.",
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      "text": "“the seriousness of DIPL” - “the results can be deadly” — Gonzalez-Rothi et al.",
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      "text": "Source: https://www.echelon-inc.com/drug-induced-phospholipidosis/",
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      "text": "The seriousness of DIPL can be explained in the case study reported by Gonzalez-Rothi et al. in the 1990s, in which a 62-year old woman was admitted to a Florida hospital with difficulty breathing. Her condition was first misdiagnosed as bronchitis. A year later, with multiple admissions to the hospital, it was identified that her breathing condition was actually the result of phospholipidosis. In her case, it was triggered by the antidepressant fluoxetine hydrochloride (Prozac™) which she had been taking on-and-off throughout the year2. DIPL is a reversible process; however, if not caught in time, the results can be deadly3.",
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      "text": "Why does phospholipidosis matter?",
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