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      "text": "Similarly, neither the FDA nor EMA ever mentioned the risk of drug-induced phospholipidosis, which causes inflammatory reactions – which are of course associated with elevated eosinophils.",
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      "text": "Essentially, drug-induced phospholipidosis is characterized by phospholipid accumulation in affected tissue of which lung, liver, brain, kidney, cornea and others have been reported [3].",
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      "text": "Similarly, neither the FDA nor EMA ever mentioned the risk of drug-induced phospholipidosis, which causes inflammatory reactions – which are of course associated with elevated eosinophils. Pitolisant trials and papers are also radio silent on phospholipidosis. which is highlighted in the literature on H3 receptor antagonists/inverse agonists as a toxicity inherent to the class, particularly drug candidates with a piperidine ring as is the case with pitolisant. Drug-induced phospholipidosis is characterized by the pathological accumulation of phospholipids (fatty molecules) in the tissues, particularly in the lungs given the association of pneumocytes (cells that comprise most of the inner surface of the lungs).",
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      "text": "Abstract Drug-induced phospholipidosis is characterized by intracellular accumulation of phospholipids with lamellar bodies, most likely from an impaired phospholipid metabolism of the lysosome. Organs affected by phospholipidosis exhibit inflammatory reactions and histopathological changes. Despite significant",
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      "text": "Drug-induced phospholipidosis is characterized by intracellular accumulation of phospholipids with lamellar bodies, most likely from an impaired phospholipid metabolism of the lysosome. Organs affected by phospholipidosis exhibit inflammatory reactions and histopathological changes. — Research literature on drug-induced phospholipidosis",
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