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  "documentTitle": "Harmony Biosciences (HRMY)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2023-03-28 00:00:00",
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  "notes": "The slide presents a direct quote from a PK expert to undermine the validity of the company's safety assertions.",
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      "text": "PK expert indicated Harmony’s claims of cardiac safety are meaningless without relevant pharmacokinetic parameters",
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      "text": "The pharmacokinetics consultant expressed concern that actual peak plasma levels are unknown, and that Harmony’s hERG/cardiac safety claims “are quite meaningless without key peak and AUC information across patients.”",
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      "text": "So all of these careful and rather elegant in vitro/ex vivo and animal model studies for hERG are quite meaningless without key peak and AUC information across patients. I don't know how they got away with this honestly...",
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      "text": "“So all of these careful and rather elegant in vitro/ex vivo and animal model studies for hERG are quite meaningless without key peak and AUC information across patients. I don't know how they got away with this honestly.” — Pharmacokinetic consultant",
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      "text": "Source: Pharmacokinetic analysis commissioned by Scorpion Capital",
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