{
  "docId": "019dd923-622c-750b-8b98-17b017c6aac8",
  "docSlug": "384ff8288d23",
  "documentTitle": "Acutus Medical Inc. (AFIB)",
  "authorId": "53_Kerrisdale_Capital",
  "authorName": "Kerrisdale Capital",
  "documentKindSlug": "research-note",
  "documentKindLabel": "Research note",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2021-07-01 00:00:00",
  "orientation": "portrait",
  "aspectRatio": 0.77272725,
  "pageNumber": 11,
  "pageCount": 29,
  "prevPage": 10,
  "nextPage": 12,
  "slideType": "research-note",
  "function": "diagnose_problem",
  "density": "balanced",
  "nDataPoints": 4,
  "notes": "The slide serves as a critical analysis of current medical standards, positioning Acutus as a solution to the identified clinical void.",
  "elementsJson": [
    "paragraph",
    "footnote"
  ],
  "metadataConfidence": 0.95,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b98-17b017c6aac8/11",
  "deckHref": "/decks/019dd923-622c-750b-8b98-17b017c6aac8",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b98-17b017c6aac8.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b98-17b017c6aac8#slide-11",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "Because of this, there is currently no consensus standard of care for ablation of persistent AF, or redo procedures of any kind, beyond PVI.",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd952-fb8f-761b-afcc-ba89e8630218",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.205,
        "w": 0.766,
        "x": 0.117,
        "y": 0.442
      },
      "kind": "paragraph",
      "text": "Since Haïssaguerre, the holy grail of AF research has been finding the non-PV triggers of AF... The 2017 Expert Consensus Statement on Ablation, therefore, does not unequivocally recommend ablation for persistent AF... Into this void has stepped Acutus.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "061696d9-4502-4ba5-a385-c68a10202a0b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.155,
        "w": 0.766,
        "x": 0.117,
        "y": 0.275
      },
      "kind": "paragraph",
      "text": "One approach in paroxysmal patients who relapse into arrhythmia is to redo the ablation... there is currently no consensus standard of care for ablation of persistent AF, or redo procedures of any kind, beyond PVI.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "28a929f9-8ab9-4e8d-bcf7-3ecfddd81732",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.155,
        "w": 0.766,
        "x": 0.117,
        "y": 0.108
      },
      "kind": "paragraph",
      "text": "But at ~65% effectiveness (with the aid of AADs), both approaches are still far from perfect in halting persistent AF... long term effectiveness is even lower than the headline numbers.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ac7c9dd6-39cb-403a-a699-0a4a2dbfea26",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "definitive evidence of the benefit or superiority of any of these techniques [beyond re-isolating the PVs] over the others is lacking...Data on current clinical practice confirm the prevailing uncertainty regarding the best reablation technique. — 2017 Expert Consensus Statement on Ablation",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd952-fb8f-761b-afcc-bc3e14c983b3",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.185,
        "w": 0.766,
        "x": 0.117,
        "y": 0.723
      },
      "kind": "source-note",
      "text": "11 It's easy to forget at times that ablation is the attempt to permanently scar cardiac tissue... 12 See Kuck, KH et al Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation... 13 We use the term “trigger” in this report...",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "66503361-189d-4f91-adc0-8f5d71239bef",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}