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  "docSlug": "9b248b07037e",
  "documentTitle": "CareDx, Inc. (CDNA)",
  "authorId": "53_Kerrisdale_Capital",
  "authorName": "Kerrisdale Capital",
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  "presentationDate": "2019-07-01 00:00:00",
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  "pageNumber": 18,
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  "density": "balanced",
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  "notes": "The slide presents specific clinical data points (sample sizes, hit rates, false positives) to undermine the clinical validity of the AlloSure test.",
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  "slideHref": "/slides/019dd923-622c-750b-8b98-0c85e40ec39b/18",
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      "kind": "callout",
      "text": "In other words, in the population of protocol biopsies at CU, AlloSure had a 0% hit rate.",
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      "kind": "list",
      "text": "In a poster presented at the American Transplant Conference earlier this month, Moinuddin and his colleagues compared the results of AlloSure with the diagnosis of the Molecular Microscope... The study used 50 'for-cause' biopsy samples... sensitivity was only 59%",
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      "text": "The University of Colorado (CU) is in the midst of conducting a study on 150 transplant patients... Of 19 indication-biopsies... 4 were diagnosed as rejection... only 2 of these tested positive... 3 AlloSure results were positive, but all 3 were false positives.",
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      "kind": "paragraph",
      "text": "with a biopsy. This is data that could help with assessing the utility of AlloSure in subclinical rejection. We suspect that the lack of published data is indicative of AlloSure's ineffectiveness in subclinical rejection.",
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      "kind": "source-note",
      "text": "22 The abstract can be found here.",
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      "name": "Cost Of Inaction",
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