{
  "docId": "019dd923-622c-750b-8b97-e9d223c0ba42",
  "docSlug": "88a4417a0cf1",
  "documentTitle": "Apellis Pharmaceuticals (APLS)",
  "authorId": "52_Citron_Research",
  "authorName": "Citron Research",
  "documentKindSlug": "research-note",
  "documentKindLabel": "Research note",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2023-11-06 00:00:00",
  "orientation": "portrait",
  "aspectRatio": 0.77295077,
  "pageNumber": 5,
  "pageCount": 13,
  "prevPage": 4,
  "nextPage": 6,
  "slideType": "expose_contradiction",
  "function": "expose_contradiction",
  "density": "dense",
  "nDataPoints": 3,
  "notes": "Includes a screenshot of a presentation slide from Dr. William Johnson and a donut chart showing 83% vs 17% sentiment.",
  "elementsJson": [
    "donut_chart",
    "paragraph",
    "screenshot"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b97-e9d223c0ba42/5",
  "deckHref": "/decks/019dd923-622c-750b-8b97-e9d223c0ba42",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b97-e9d223c0ba42.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b97-e9d223c0ba42#slide-5",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "Wolfe Clinic recognized complications in 1 in 28 per injection. His conclusion that Syfovre should immediately get a warning label or get paused altogether.",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-1ac1-76e9-bcd7-1719631d1276",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.336,
        "w": 0.536,
        "x": 0.232,
        "y": 0.1
      },
      "kind": "chart",
      "text": "Current Complement Inhibition Therapy for Geographic Atrophy Is Acceptable: 83% Pro, 17% Con",
      "attrs": null,
      "subkind": "donut",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "49cb73f3-152c-41f8-bc3e-d42e37a21e97",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.212,
        "w": 0.733,
        "x": 0.133,
        "y": 0.628
      },
      "kind": "image",
      "text": "Introduction slide from Dr. William Johnson's presentation",
      "attrs": null,
      "subkind": "screenshot",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "abf0066c-fcd9-44ac-838b-af414a4654db",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "metric",
      "text": "ophthalmologist sentiment: 83%",
      "attrs": null,
      "subkind": "primary",
      "toolName": "Quantification",
      "toolSlug": "quantification",
      "confidence": null,
      "componentId": "019dd953-1ac1-76e9-bcd7-1ebd1b6fa2ff",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.764,
        "x": 0.118,
        "y": 0.437
      },
      "kind": "paragraph",
      "text": "In a presentation later in the day entitled “Late Breaking Developments” Dr. William Johnson of the Wolfe Eye Clinic presented a critical analysis of Syfovre entitled, “Syfovre Initial Complication Experience”",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "5aa20939-5c62-4523-a8bc-2f3ebfe1ccc5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.764,
        "x": 0.118,
        "y": 0.87
      },
      "kind": "paragraph",
      "text": "Wolfe Clinic recognized complications in 1 in 28 per injection. His conclusion that Syfovre should immediately get a warning label or get paused altogether.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "bb8ecab3-5a58-4a23-b4ae-33e5a5339e08",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "Syfovre Initial Complication Experience — Dr. William Johnson",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd953-1ac1-76e9-bcd7-1af61ce8ca16",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.445,
        "x": 0.118,
        "y": 0.39
      },
      "kind": "title",
      "text": "But Wait....It Gets Worse",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c4ff7bfc-bc0a-4f79-9f65-b8ca4dbf9ad5",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 5,
      "from": 2,
      "beatId": "35b7911a-b113-4112-9253-57c0fd4ab885",
      "arcName": "Overcoming the Monster",
      "arcSlug": "overcoming-monster",
      "beatName": "The Monster",
      "beatSlug": "overcoming-monster-the-monster",
      "evidence": "The document presents Syfovre's complications as the central problem to be addressed.",
      "position": 0,
      "confidence": 0.8,
      "parentBeatName": "Hook",
      "parentBeatSlug": "hook"
    }
  ],
  "loops": [
    {
      "to": 13,
      "from": 1,
      "name": "Cost Of Inaction",
      "slug": "27-cost-of-inaction",
      "bestFor": "Urgent budget requests, compliance, risk mitigation",
      "matchId": "1b08b18b-190c-48b4-b339-4e33de995cac",
      "evidence": "The document implies that failure to address Syfovre's complications could lead to regulatory action and reputational damage.",
      "position": 1,
      "objective": "What are the consequences of not taking action against Syfovre's safety concerns?",
      "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
      "confidence": 0.6,
      "description": "Quantify what happens if the audience does nothing"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}