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  "documentTitle": "Chinook Therapeutics Inc (KDNY)",
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  "notes": "The text highlights discrepancies in reported ESKD numbers between different sources and questions the statistical significance of the primary renal outcome.",
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      "text": "Atrasentan’s direct effect on rates of advancement to end-stage kidney disease, as the below table taken from the SONAR analysis shows, does not reach statistical significance.",
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      "text": "p-value: 0.06",
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      "text": "Atrasentan's direct effect on rates of advancement to end-stage kidney disease, as the below table taken from the SONAR analysis shows, does not reach statistical significance.",
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      "text": "end-stage renal disease in the atrasentan versus the placebo cohort, only a numerical difference of 14 patients and a p-value of 0.06 with a percentage difference of 5.1% to 6.1% of patients.",
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      "text": "44 https://repo.dma.dp.ua/6035/1/SONAR.pdf 45 https://repo.dma.dp.ua/6035/1/SONAR.pdf 46 https://clinicaltrials.gov/ct2/show/results/NCT01858532?term=atrasentan&draw=2&rank=5",
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