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  "documentTitle": "Chinook Therapeutics Inc (KDNY)",
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      "text": "It is likely that if sparsentan is found to be ultimately inefficacious, it will be inefficacious for the same reasons as atrasentan; if, on the other hand, it is found to be efficacious, it will block the path for atrasentan’s approval for the next seven years.",
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      "text": "Recent findings published by Travere call into question the long-term renal benefits of sparsentan. This is not, as it may at first seem, good news for Chinook, because the deficits in sparsentan's action are consistent with those in atrasentan.",
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      "text": "It seems exceedingly unlikely that a drug with a side effect history as benign as sparsentan will be replaced by atrasentan, with its history of heart failures and excess mortality.",
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      "text": "AbbVie and Chinook appear to use manipulated graphs to prove their claims for atrasentan. There is a very sharp decline in numbers of patients assessed at various treatment points on important metrics for unclear reasons.",
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      "text": "“No evidence of hepatic toxicity” — Chinook Company Conference Presentation, May 10, Pg. 5",
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