{
  "docId": "019dd923-5fed-74f2-a970-22e81ff63ce8",
  "docSlug": "bi-afad71c64ca4f4b7",
  "documentTitle": "Meliora Therapeutics pitch deck: $11 million seed round",
  "authorId": "Pitchdecks",
  "authorName": "Meliora Therapeutics",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "strategy_consulting",
  "sourceTypeLabel": "Strategy consulting",
  "presentationDate": null,
  "orientation": "landscape",
  "aspectRatio": 1.777,
  "pageNumber": 11,
  "pageCount": 14,
  "prevPage": 10,
  "nextPage": 12,
  "slideType": "traction",
  "function": "show_traction",
  "density": "overcrowded",
  "nDataPoints": 3,
  "notes": "The slide uses a two-column layout to contrast Efficacy and Safety results.",
  "elementsJson": [
    "headline_text",
    "paragraph",
    "callout_box",
    "icon_grid"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-5fed-74f2-a970-22e81ff63ce8/11",
  "deckHref": "/decks/019dd923-5fed-74f2-a970-22e81ff63ce8",
  "deckJsonHref": "/decks/019dd923-5fed-74f2-a970-22e81ff63ce8.json",
  "deckAnchorHref": "/decks/019dd923-5fed-74f2-a970-22e81ff63ce8#slide-11",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "MELIORA'S PROPRIETARY COMPOUNDS HAVE ACHIEVED SINGLE DIGIT NANOMOLAR POTENCY AGAINST CDK11, A NOVEL KINASE TARGET, IN 9 MONTHS WITH $125K",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd952-c5b0-71fc-abf8-2e675c363c67",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.12,
        "w": 0.08,
        "x": 0.66,
        "y": 0.53
      },
      "kind": "image",
      "text": "Shield icon for safety",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "0fa95dff-05cb-4934-b883-daaaf2a237ab",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.12,
        "w": 0.08,
        "x": 0.26,
        "y": 0.53
      },
      "kind": "image",
      "text": "Mouse icon for efficacy",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "afd3fe95-bc6d-4521-98ec-f631c2e25b2e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.62,
        "x": 0.19,
        "y": 0.38
      },
      "kind": "list",
      "text": "Efficacy vs Safety",
      "attrs": null,
      "subkind": "comparison",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "cc83be9e-88b2-47e4-810f-57d518e29b1a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "metric",
      "text": "development time: 9 months",
      "attrs": null,
      "subkind": "primary",
      "toolName": "Quantification",
      "toolSlug": "quantification",
      "confidence": null,
      "componentId": "019dd952-c5b0-71fc-abf8-316fa58ba6d5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.28,
        "x": 0.16,
        "y": 0.67
      },
      "kind": "paragraph",
      "text": "CDK11 inhibition through OTS964 treatment blocked xenograft tumor growth for triple-negative breast cancer, pancreatic cancer, and melanoma cell lines",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "09f640ba-933d-4661-afdc-8637ff0031cd",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.28,
        "x": 0.56,
        "y": 0.67
      },
      "kind": "paragraph",
      "text": "CDK11 inhibition induced no measurable tox at therapeutically efficacious doses in a mouse model, including inspection of brain, heart, liver, lung tissue",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "90a05668-f030-4a6a-9960-e39608f33f3f",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.9,
        "x": 0.05,
        "y": 0.27
      },
      "kind": "paragraph",
      "text": "MELIORA'S PROPRIETARY COMPOUNDS HAVE ACHIEVED SINGLE DIGIT NANOMOLAR POTENCY AGAINST CDK11, A NOVEL KINASE TARGET, IN 9 MONTHS WITH $125K",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b564fdd7-7b7e-4b71-b94b-655923b148c5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.9,
        "x": 0.05,
        "y": 0.13
      },
      "kind": "title",
      "text": "MELIORA'S FIRST PROOF-OF-CONCEPT ASSET IS A CDK11 INHIBITOR THAT LEVERAGES KNOWN SAFETY SIGNAL FOR THE STARTING SCAFFOLD",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ff74a5d6-b1a6-4c01-8e81-0b23cbd06ac8",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 11,
      "from": 8,
      "beatId": "9687389a-6e9c-4b2d-b2fe-60ec97274b69",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Evidence & Proof",
      "beatSlug": "consultants-gambit-evidence-proof",
      "evidence": "Data generated to date, validation of Meliora's ability",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Evidence",
      "parentBeatSlug": "evidence"
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}