{
  "docId": "019dd923-5fec-763b-95cf-36829236392e",
  "docSlug": "wmIz1K5649XDm8N1ElWG",
  "documentTitle": "See the 24-slide pitch deck a new biotech startup just used to raise $175 million to develop the next cancer breakthrough",
  "authorId": "Pitchdecks",
  "authorName": "Affini-T",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "strategy_consulting",
  "sourceTypeLabel": "Strategy consulting",
  "presentationDate": null,
  "orientation": "landscape",
  "aspectRatio": 1.782,
  "pageNumber": 4,
  "pageCount": 24,
  "prevPage": 3,
  "nextPage": 5,
  "slideType": "problem_statement",
  "function": "frame_problem",
  "density": "balanced",
  "nDataPoints": 0,
  "notes": "Uses a gear metaphor to represent biological mechanisms; the broken gear represents the disruption of these mechanisms.",
  "elementsJson": [
    "headline_text",
    "action_title",
    "bullet_list",
    "other"
  ],
  "metadataConfidence": 0.9,
  "imagePath": null,
  "slideHref": "/slides/019dd923-5fec-763b-95cf-36829236392e/4",
  "deckHref": "/decks/019dd923-5fec-763b-95cf-36829236392e",
  "deckJsonHref": "/decks/019dd923-5fec-763b-95cf-36829236392e.json",
  "deckAnchorHref": "/decks/019dd923-5fec-763b-95cf-36829236392e#slide-4",
  "components": [
    {
      "bbox": {
        "h": 0.3,
        "w": 0.3,
        "x": 0.6,
        "y": 0.6
      },
      "kind": "image",
      "text": "Broken gear icon with prohibition sign",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "36937b62-0650-48ce-aa90-e8e30dc68583",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.6,
        "w": 0.4,
        "x": 0.05,
        "y": 0.25
      },
      "kind": "image",
      "text": "Gears representing Tumor Growth, Oncogenic Driver Mutations, and Immunosuppression",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "3c26c676-539e-484e-a813-eb5b67b91ce0",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.4,
        "w": 0.5,
        "x": 0.45,
        "y": 0.25
      },
      "kind": "list",
      "text": "Oncogenic driver mutations are fundamental to tumor biology - critical for rapid growth and metastasis. Engineered immune cells targeting oncogenic driver mutations, like KRAS, minimize potential tumor escape mechanisms. We combine a validated TCR discovery platform with synthetic biology switches to attack tumor biology at its root cause.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e7ab2fc8-57ed-4492-a9de-2884d5038586",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.9,
        "x": 0.05,
        "y": 0.13
      },
      "kind": "title",
      "text": "Tumor growth powered by oncogenic driver mutations and immune cell dysfunction",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "3da0bbf3-f1a5-496c-971d-f18a700b7fa6",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 4,
      "from": 4,
      "beatId": "700c8a69-b422-4d04-8d71-6231ff9039a9",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Problem Statement",
      "beatSlug": null,
      "evidence": "Clearly defines the problem of tumor growth powered by oncogenic driver mutations",
      "position": 0,
      "confidence": 0.8,
      "parentBeatName": null,
      "parentBeatSlug": null
    }
  ],
  "loops": [
    {
      "to": 6,
      "from": 4,
      "name": "Cost Of Inaction",
      "slug": "27-cost-of-inaction",
      "bestFor": "Urgent budget requests, compliance, risk mitigation",
      "matchId": "31e0b531-be4a-4a81-9079-49b055f4a596",
      "evidence": "Emphasizes the limitations of current treatments and the potential of Affini-T's T cell therapies",
      "position": 0,
      "objective": "Highlights the need for better cancer treatments",
      "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
      "confidence": 0.6,
      "description": "Quantify what happens if the audience does nothing"
    },
    {
      "to": 5,
      "from": 3,
      "name": "Golden Circle",
      "slug": "11-golden-circle",
      "bestFor": "Visionary leadership, brand positioning, mission statements",
      "matchId": "a51a49e1-5271-4281-b207-0de93fbc5072",
      "evidence": "Connects Affini-T's mission to the potential for transformative therapies",
      "position": 1,
      "objective": "Explains the 'why' behind Affini-T's mission",
      "structure": "The Why (Belief) -> The How (Process) -> The What (Result)",
      "confidence": 0.6,
      "description": "Invert the typical pitch by starting with why you exist, rather than what you do"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}