{ "docId": "019dd923-5ddf-7308-8fca-22416b252552", "docSlug": "d3299d4378fafc22", "documentTitle": "Megatrend 2 Health & Care", "authorId": "RolandBerger", "authorName": "Roland Berger", "documentKindSlug": "consulting-deck", "documentKindLabel": "Consulting deck", "sourceTypeSlug": "strategy_consulting", "sourceTypeLabel": "Strategy consulting", "presentationDate": null, "orientation": "landscape", "aspectRatio": 1.778, "pageNumber": 35, "pageCount": 59, "prevPage": 34, "nextPage": 36, "slideType": "industry_trends", "function": "present_solution", "density": "overcrowded", "nDataPoints": 1, "notes": "Includes a sidebar navigation element indicating this is section 2 of a larger deck.", "elementsJson": [ "headline_text", "paragraph", "icon_grid", "other" ], "metadataConfidence": 0.95, "imagePath": null, "slideHref": "/slides/019dd923-5ddf-7308-8fca-22416b252552/35", "deckHref": "/decks/019dd923-5ddf-7308-8fca-22416b252552", "deckJsonHref": "/decks/019dd923-5ddf-7308-8fca-22416b252552.json", "deckAnchorHref": "/decks/019dd923-5ddf-7308-8fca-22416b252552#slide-35", "components": [ { "bbox": null, "kind": "callout", "text": "The first mRNA-based vaccine for the Corona virus was developed within 4 days.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd951-e590-72ba-a112-91a7854cebbd", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.35, "w": 0.2, "x": 0.18, "y": 0.4 }, "kind": "image", "text": "Diagram of mRNA structure", "attrs": null, "subkind": "illustration", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6ea6e7b0-67aa-4fd9-adeb-96aff19cdf4e", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.35, "x": 0.16, "y": 0.24 }, "kind": "list", "text": "RNA platform characteristic: An mRNA vaccine consists of a (non-replicating) messenger RNA strand that codes for a disease-specific antigen.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0584b40e-3c03-487f-aa24-d8044648ad98", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.2, "x": 0.4, "y": 0.42 }, "kind": "list", "text": "Built for speed: The first mRNA-based vaccine for the Corona virus was developed within 4 days.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0924cdb6-6ad5-4aea-a22f-7516ebe67e06", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.4, "x": 0.16, "y": 0.8 }, "kind": "list", "text": "Self-amplifying functionality (saRNA): Self-amplifying RNA (saRNA) replicates itself in the body, which helps overcome some of mRNAs vaccination volume and distribution challenges.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6c332880-f54b-48c1-92e1-cb03869567b8", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.35, "x": 0.63, "y": 0.8 }, "kind": "list", "text": "Rare diseases: Mostly caused by genetic defects, individuals suffering from rare diseases lack specific intracellular proteins which they cannot produce themselves.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "89d0f207-d498-401c-b866-5d04f409cc35", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.35, "x": 0.63, "y": 0.24 }, "kind": "list", "text": "Oncology: Based on a tumor sample, an individually tailored mRNA vaccine leads to an immune response attacking cancer cells in a specific tumor.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "bf3f4684-5a63-4e80-a4cc-1380870be5bc", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.2, "w": 0.35, "x": 0.63, "y": 0.45 }, "kind": "list", "text": "Infectious diseases and prophylactic usage: Since mRNA vaccines are easy to adapt to infectious diseases at speed, their potential to fight seasonal infectious respiratory diseases such as influenza is high.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "c3bbb8da-f295-4b95-8fb1-7141e73f6087", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.2, "x": 0.4, "y": 0.65 }, "kind": "list", "text": "Plug and play functionality: The RNA platform makes it possible to develop new vaccines rapidly while easily testing hypotheses.", "attrs": null, "subkind": "bullet", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "c71a8656-ccb5-4266-9ebc-a592317a7598", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.3, "x": 0.63, "y": 0.18 }, "kind": "paragraph", "text": "Potential RNA opportunities", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "384a088f-1139-4642-9e20-4daa52942ba3", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.3, "x": 0.16, "y": 0.18 }, "kind": "paragraph", "text": "RNA vaccine technologies: mRNA / saRNA", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "bffb1ca6-461d-49a6-984b-3418fe25a642", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.4, "x": 0.16, "y": 0.97 }, "kind": "source-note", "text": "Sources: Nature; The Atlantic; Human Gene Therapy; PHG Foundation; Roland Berger", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0db834cf-62b5-40c2-a733-581f880db963", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.1, "w": 0.8, "x": 0.16, "y": 0.05 }, "kind": "title", "text": "The resounding success of RNA vaccines in the COVID-19 pandemic attests to the future potential of RNA vaccines for cancer and other treatments", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6c76440f-86eb-428d-bcb3-d77324294a47", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [ { "name": "List presentation", "slug": "list-presentation", "agent": null, "layer": "slide", "matchId": "e6495c20-b943-4316-95cf-ce8fa230fec5", "evidence": "The slide presents several bullet points listing the characteristics and potential applications of RNA vaccines.", "confidence": 0.8 } ], "frameworks": [], "arcBeats": [ { "to": 59, "from": 13, "beatId": "fe83908c-b98c-42c7-8a4f-1fbadc16fd17", "arcName": "Problem-Agitate-Solution", "arcSlug": "problem-agitate-solution", "beatName": "Solution (Provide relief)", "beatSlug": "problem-agitate-solution-solution-provide-relief", "evidence": "The deck provides potential solutions to the challenges in the healthcare sector, 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