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        "evidence": "Transforming the Development of Therapeutics With the 23andMe Database",
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        "agent": "Storyteller",
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        "whenToUse": "Any narrative-driven persuasive deck whose job is to move the audience: keynotes, fundraising pitches, capital-allocation board asks, all-hands behaviour-change talks, conference talks meant to shift mental models. Use it before structuring; pair with Pyramid when the deck must also withstand line-by-line scrutiny.",
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        "tool": {
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          "description": "Context → Conflict → Insight → Implication structure for data narratives",
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          "categoryName": "Loop",
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        "evidence": "750k Consumers participated in the COVID-19 study in the first 90 days",
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        "matchId": "6d3fc172-8760-4253-ad8f-15902de35314",
        "evidence": "Genome-Wide Association Studies (GWAS) is a statistical analysis of Single Nucleotide Polymorphisms (SNPs)",
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        "evidence": "Number of independent hits p<5e-8 from 2015 to 2020",
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        "confidence": 0.7,
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        "matchId": "4e9f819b-86f5-44d1-9fdb-ae6e0cd183aa",
        "evidence": "Grid of clinical phenotype data visualizations",
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        "confidence": 0.8,
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          "bestFor": null,
          "canonId": "019dd956-9e98-7269-907b-8cf727e9499d",
          "version": 1,
          "bodyDocId": null,
          "description": "Showing how one event leads to another in sequence",
          "familyLabel": null,
          "categoryName": "Loop",
          "categorySlug": "loop"
        },
        "agent": "Architect",
        "layer": "slide",
        "agents": [
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        ],
        "matchId": "f7fc1a42-9454-4489-aa42-1225892ad9a0",
        "evidence": "TSLP signaling pathway diagram",
        "pageRefs": null,
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        "whenToUse": null,
        "confidence": 0.6,
        "extraction": {
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        "tool": {
          "name": "NxN matrix",
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          "bestFor": null,
          "canonId": "019de52d-2313-71fa-bb45-a7d1a4aae23a",
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        "matchId": "aee55cdf-8198-4f25-9135-c0764de25cb3",
        "evidence": "TSLP PheWAS heatmap showing log(OR) values",
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        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:21:31.806162+00",
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      {
        "tool": {
          "name": "Flywheel",
          "slug": "flywheel",
          "status": "active",
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          "canonId": "019de52d-1ad8-75ab-9027-a40365590152",
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        "matchId": "1923b1a8-1f86-46aa-b7e6-a0528ee3c18f",
        "evidence": "Systematic, Scalable Research Platform Yields Novel Drug Targets",
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        "whenToUse": null,
        "confidence": 0.6,
        "extraction": {
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        "whyItWorks": null,
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      {
        "tool": {
          "name": "2x2 matrix",
          "slug": "matrix-2x2",
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          "canonId": "019dd9e1-50ab-72d1-8afb-3ab0a38e32a8",
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          "description": "BCG matrix, importance/urgency, any axes-and-quadrants frame.",
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        "matchId": "12c543af-133d-4d4f-808a-ffed74a34ed9",
        "evidence": "Heatmap showing genetic associations with autoimmune and cancer phenotypes",
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        "whenToUse": null,
        "confidence": 0.5,
        "extraction": {
          "at": "2026-07-17 00:21:32.013235+00",
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        "cardinality": "common",
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        "tool": {
          "name": "Audience Definition",
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          "bestFor": null,
          "canonId": "019dd956-7f2a-775d-aeee-ff099bcb7756",
          "version": 1,
          "bodyDocId": null,
          "description": "Six key questions: Who are they? What do they know? What do they believe? What do they care about? What do they fear? What decisions can they make?",
          "familyLabel": null,
          "categoryName": "Block",
          "categorySlug": "block"
        },
        "agent": "Storyteller",
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        "agents": [
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        ],
        "matchId": "2369bf4e-7228-4a63-91fd-3eb236ac77d2",
        "evidence": "CD200R1 is an inhibitory receptor expressed on T-cells and myeloid cells.",
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        "confidence": 0.7,
        "extraction": {
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      {
        "tool": {
          "name": "Before/after framing",
          "slug": "before-after-framing",
          "status": "active",
          "bestFor": "For turnaround / reform proposals",
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          "description": "You visualise two futures side by side: the trajectory the target is on\ntoday, and the trajectory under your proposed intervention. The reader\nhas to see the delta to feel the stakes.\n\nIt's the rhetorical cousin of the peer-gap — same visual grammar\n(comparison), but across **time** instead of across peers.",
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        "matchId": "ecf708d5-5571-4b66-9ef8-fdd2c33383c3",
        "evidence": "Blocking the CD200R1 pathway enhanced IFNy production from SEB-stimulated PBMCs compared to isotype control and anti-PD1 in the majority of samples tested",
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        "priority": null,
        "whenToUse": "For turnaround / reform proposals",
        "confidence": 0.7,
        "extraction": {
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        "pageNumber": 44,
        "whyItWorks": "- It **quantifies the opportunity cost** of inaction. \"Doing nothing\"\n  becomes a concrete, visible path, not an abstraction.\n- It **makes the Answer tangible**. The prescription isn't a paragraph;\n  it's a trajectory the reader can point at.\n- It **pre-empts the status-quo defence**. Management usually argues \"we\n  have a plan\". Your chart shows what their plan looks like vs. yours.\n- It **satisfies both the Architect** (math adds up) **and the Storyteller**\n  (emotional delta between two futures).",
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      {
        "tool": {
          "name": "Thesis archetype",
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          "canonId": "019dd9e1-4b0b-7428-9b26-f171d1e753fb",
          "version": 1,
          "bodyDocId": null,
          "description": "A canonical investment / activist thesis shape (breakup, fraud, governance).",
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        },
        "agent": null,
        "layer": "slide",
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        "matchId": "9e69eeca-2186-455f-b75f-6045d50b299e",
        "evidence": "CD200R1 is an immune checkpoint with a strong I/O signature in three components of the pathway.",
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        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
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        "pageNumber": 46,
        "whyItWorks": null,
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        "cardinality": "optional",
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        "tool": {
          "name": "Table data",
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          "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
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          "description": "Tabular layouts of structured data.",
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