{ "schemaVersion": "deck-intelligence.v1", "id": "019de073-e8d5-735f-8ffd-8a5102406a96", "slug": "3003a94fa3be7c8f2ff0fbac5a54b26e", "title": "Arbutus Biopharma | Results Presentation Deck | 15 slides", "subtitle": "Arbutus Biopharma · 2022-11", "author": "Arbutus Biopharma", "date": "2022-11-01 00:00:00", "pageCount": 15, "kind": "conference-presentation", "orientation": "landscape", "aspectRatio": 1.7777778, "document": { "id": "019de073-e8d5-735f-8ffd-8a5102406a96", "slug": "3003a94fa3be7c8f2ff0fbac5a54b26e", "title": "Arbutus Biopharma | Results Presentation Deck | 15 slides", "rawTitle": "Arbutus Biopharma | Results Presentation Deck | 15 slides", "authorId": "arbutus-biopharma", "authorName": "Arbutus Biopharma", "authorDisplay": "Arbutus Biopharma", "kind": { "slug": "conference-presentation", "label": "Conference presentation" }, "sourceType": { "slug": "investor_relations", "label": "Investor relations" }, "fileName": "2022-11__arbutus-biopharma__results__3003a94f.pdf", "sourceUrl": "https://www.slidebook.io/company/arbutus-biopharma/presentation/3003a94fa3be7c8f2ff0fbac5a54b26e/", "sourceDate": "2022-11-04 00:00:00", "presentationDate": "2022-11-01 00:00:00", "ingestedAt": "2026-04-30 22:13:05.978841+00", "status": "ready", "pageCount": 15, "orientation": "landscape", "aspectRatio": 1.7777778, "targetCompany": null, "targetTicker": null, "metadata": { "corpus": "slidebook", "industry": "biotechnology", "local_root": "/Users/miguelsuredasuau/Desktop/lalalalla/_scrape/slidebook/decks/2022-11__arbutus-biopharma__results__3003a94f", "image_width": 1920, "image_format": "jpg", "deck_type_raw": "Results Presentation Deck", "deck_type_slug": null, "source_url_pattern": "https://www.slidebook.io/company/{company_slug}/presentation/{deck_id}/" } }, "coverage": { "pageCount": 15, "pagesIndexed": 15, "pagesWithImages": 15, "pagesWithMetadata": 15, "imageCoveragePct": 100, "metadataCoveragePct": 100, "componentCount": 55, "chartCount": 6, "metricSlides": 0, "toolMatches": 7, "documentToolMatches": 0, "frameworkMatches": 2, "arcMatches": 0, "beatMatches": 0, "loopMatches": 0, "patternMatches": 0, "storymakersMatch": false, "scoreAvailable": false, "reviewAvailable": false, "activistThesisAvailable": false, "pitchdeckMetadataAvailable": false, "pitchdeckProfileAvailable": false }, "blocks": [], "matches": { "arcs": [], "beats": [], "loops": [], "tools": [ { "tool": { "name": "List presentation", "slug": "list-presentation", "status": "active", "bestFor": null, "canonId": "019dd9e1-4ef7-777d-ba68-9074c2b3bcf1", "version": 1, "bodyDocId": null, "description": "Bulleted, numbered, or checklist enumerations.", "familyLabel": null, "categoryName": null, "categorySlug": null }, "agent": null, "layer": "slide", "agents": null, "matchId": "b14c59be-4362-484e-9e38-88e1aa2d471b", "evidence": "list/bullet: Mean declines in HBsAg on treatment and post treatment continue to be comparable across cohorts.", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.9, "extraction": { "at": "2026-07-17 00:14:33.480073+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 4, "whyItWorks": null, "antipattern": null, "cardinality": "common", "narrativePurpose": null }, { "tool": { "name": "List presentation", "slug": "list-presentation", "status": "active", "bestFor": null, "canonId": "019dd9e1-4ef7-777d-ba68-9074c2b3bcf1", "version": 1, "bodyDocId": null, "description": "Bulleted, numbered, or checklist enumerations.", "familyLabel": null, "categoryName": null, "categorySlug": null }, "agent": null, "layer": "slide", "agents": null, "matchId": "7cd4531a-f980-4c0d-922c-d07b00af0a4d", "evidence": "list/bullet: AB-729 generally safe and well-tolerated in clinical trial after single and repeat doses", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.9, "extraction": { "at": "2026-07-17 00:14:33.631928+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 7, "whyItWorks": null, "antipattern": null, "cardinality": "common", "narrativePurpose": null }, { "tool": { "name": "List presentation", "slug": "list-presentation", "status": "active", "bestFor": null, "canonId": "019dd9e1-4ef7-777d-ba68-9074c2b3bcf1", "version": 1, "bodyDocId": null, "description": "Bulleted, numbered, or checklist enumerations.", "familyLabel": null, "categoryName": null, "categorySlug": null }, "agent": null, "layer": "slide", "agents": null, "matchId": "f2bfa252-0587-4e8d-af4e-15decee66785", "evidence": "list/bullet: Unique, proprietary GalNAc delivery technology; Robust reduction in HBsAg; HBsAg/HBV DNA sustained; Immune activity; Generally safe and well-tolerated", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.9, "extraction": { "at": "2026-07-17 00:14:33.708382+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 8, "whyItWorks": null, "antipattern": null, "cardinality": "common", "narrativePurpose": null }, { "tool": { "name": "Three-Act Structure", "slug": "three-act-structure", "status": "active", "bestFor": null, "canonId": "019dd956-8812-7796-9105-e7bc0e405681", "version": 1, "bodyDocId": null, "description": "Setup, Confrontation, Resolution - classic dramatic structure", "familyLabel": null, "categoryName": "Block", "categorySlug": "block" }, "agent": "Storyteller", "layer": "slide", "agents": [ "Storyteller" ], "matchId": "5551628e-7953-47fd-a11d-a4fe24f4be5b", "evidence": "Primary objective: evaluate safety and tolerability of vebicorvir (VBR) in combination with AB-729 in patients with cHBV receiving NA therapy.", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.7, "extraction": { "at": "2026-07-17 00:14:59.383877+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 9, "whyItWorks": null, "antipattern": null, "cardinality": null, "narrativePurpose": null }, { "tool": { "name": "Before-After-Bridge", "slug": "before-after-bridge", "status": "active", "bestFor": null, "canonId": "019dd956-8604-7188-883f-42370288ad05", "version": 1, "bodyDocId": null, "description": "Narrative structure: Paint the before, show the after, explain the bridge", "familyLabel": null, "categoryName": "Block", "categorySlug": "block" }, "agent": "Storyteller", "layer": "slide", "agents": [ "Storyteller" ], "matchId": "2e25a7d8-2bf0-4c1c-ada5-56b305019dab", "evidence": "AB-101 treatment significantly reduces PD-L1 expression in Kupffer cells in a cHBV mouse model.", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.7, "extraction": { "at": "2026-07-17 00:14:59.52102+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 12, "whyItWorks": null, "antipattern": null, "cardinality": null, "narrativePurpose": null }, { "tool": { "name": "Before-After-Bridge", "slug": "before-after-bridge", "status": "active", "bestFor": null, "canonId": "019dd956-8604-7188-883f-42370288ad05", "version": 1, "bodyDocId": null, "description": "Narrative structure: Paint the before, show the after, explain the bridge", "familyLabel": null, "categoryName": "Block", "categorySlug": "block" }, "agent": "Storyteller", "layer": "slide", "agents": [ "Storyteller" ], "matchId": "a3d9c0b8-c8dc-4886-b4bc-fdf1a8921229", "evidence": "AB-101+ siRNA combination therapy significantly enhances HBV-specific T cell activity and HBsAb levels compared to monotherapy or vehicle.", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.7, "extraction": { "at": "2026-07-17 00:14:59.589847+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 13, "whyItWorks": null, "antipattern": null, "cardinality": null, "narrativePurpose": null }, { "tool": { "name": "Executive summary", "slug": "executive-summary", "status": "active", "bestFor": null, "canonId": "019dd9e1-4b63-72d5-9734-da757d91ca61", "version": 1, "bodyDocId": null, "description": "A condensed view of the entire argument on a single slide / block.", "familyLabel": null, "categoryName": null, "categorySlug": null }, "agent": null, "layer": "slide", "agents": null, "matchId": "c5d9725b-fc9f-446c-8628-371735337546", "evidence": "Oral small-molecule PD-L1 inhibitors have been identified which function through a novel internalization mechanism distinct from antibody approaches", "pageRefs": null, "priority": null, "whenToUse": null, "confidence": 0.9, "extraction": { "at": "2026-07-17 00:14:59.658824+00", "model": "or:meta-llama/llama-4-scout", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 14, "whyItWorks": null, "antipattern": null, "cardinality": "common", "narrativePurpose": null } ], "frameworks": [ { "matchId": "bb118213-e64a-44e3-8619-4ed7a8964888", "evidence": "The slide uses a structured list format to present key product attributes.", "framework": null, "confidence": 0.8, "extraction": { "at": "2026-05-02 12:20:39.081+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 8, "frameworkName": "list-presentation" }, { "matchId": "1c096ae0-c2e7-4166-990f-8efa7c366e2d", "evidence": "The slide maps three distinct therapeutic actions to a single outcome (HBV Cure) via a process flow.", "framework": null, "confidence": 0.85, "extraction": { "at": "2026-05-02 12:20:39.827+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "pageNumber": 11, "frameworkName": "causal-chain" } ], "patterns": [] }, "storymakers": null, "score": null, "review": null, "activistThesis": null, "pitchdeck": { "metadata": null, "profile": null }, "slides": [ { "page": 1, "type": "setup", "title": "Includes company logo, ticker, website, and date.", "function": "front_matter", "imagePath": "https://imgproxy.kitesheet.com/JaPUZItE-3boxYW34rs9w6o-3mYqjeWZHEPdB1gEs8I/rs:fit:1200:1200:0/q:82/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy8zMDAzYTk0ZmEzYmU3YzhmMmZmMGZiYWM1YTU0YjI2ZS9wMDAxLmpwZw", "rawType": "cover", "block": null, "metadata": { "slideType": "cover", "slideTypeCanon": { "name": "Cover", "slug": "cover", "status": "active", "canonId": "019de52d-05f2-729d-9f93-e0504f0a2410", "version": 1, "description": null }, "function": "front_matter", "functionCanon": { "name": "Front matter", "slug": "front_matter", "status": "active", "canonId": "019de52d-133d-73f0-9e26-201eda96b098", "version": 1, "description": null }, "density": "sparse", "densityScore": 22, "componentCount": 4, "textChars": 88, "nDataPoints": 0, "notes": "Includes company logo, ticker, website, and date.", "elementsJson": null, "confidence": 1, "extraction": { "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "at": "2026-05-02 12:20:38.246+00", "seconds": 2.365, "promptVersion": "v2-canon-conditioned" } }, "links": { "slide": "/slides/019de073-e8d5-735f-8ffd-8a5102406a96/1", "deck": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96", "deckAnchor": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96#slide-1", "deckJson": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96.json" }, "components": [ { "bbox": { "h": 0.12, "w": 0.23, "x": 0.07, "y": 0.15 }, "kind": "image", "text": "Arbutus Biopharma", "attrs": null, "canon": { "kind": { "name": "Image", "slug": "image", "status": "active", "canonId": "019de52c-f978-701f-a720-51d029d769e7", "version": 1, "description": "Photo, illustration, screenshot or icon." }, "tool": null, "subkind": { "name": "Logo", "slug": "logo", "status": "active", "canonId": "019de52c-fdaf-743d-94c4-d7c6a0e55302", "version": 1, "description": null }, "framework": null }, "subkind": "logo", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.246+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "3fdab67a-d849-4713-8ba8-b759a89feaf5", "parentComponentId": null }, { "bbox": { "h": 0.7, "w": 0.4, "x": 0.55, "y": 0.1 }, "kind": "image", "text": null, "attrs": null, "canon": { "kind": { "name": "Image", "slug": "image", "status": "active", "canonId": "019de52c-f978-701f-a720-51d029d769e7", "version": 1, "description": "Photo, illustration, screenshot or icon." }, "tool": null, "subkind": { "name": "Photo", "slug": "photo", "status": "active", "canonId": "019de52c-fd37-757f-b4a8-ca26d4888875", "version": 1, "description": null }, "framework": null }, "subkind": "photo", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.246+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "054cc5f7-6f29-45f7-87d1-6958a0e8ce72", "parentComponentId": null }, { "bbox": { "h": 0.15, "w": 0.2, "x": 0.07, "y": 0.58 }, "kind": "paragraph", "text": "NASDAQ: ABUS\nwww.arbutusbio.com\nNovember 4, 2022", "attrs": null, "canon": { "kind": { "name": "Paragraph", "slug": "paragraph", "status": "active", "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4", "version": 1, "description": "Single prose block in the body of a slide." }, "tool": null, "subkind": { "name": "Paragraph", "slug": "paragraph", "status": "active", "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433", "version": 1, "description": null }, "framework": null }, "subkind": "paragraph", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.246+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "da29a709-355c-4776-86a2-965c99527acd", "parentComponentId": null }, { "bbox": { "h": 0.2, "w": 0.3, "x": 0.07, "y": 0.35 }, "kind": "title", "text": "AASLD Data Presentation", "attrs": null, "canon": { "kind": { "name": "Title", "slug": "title", "status": "active", "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4", "version": 1, "description": "Slide title or headline." }, "tool": null, "subkind": { "name": "Headline", "slug": "headline", "status": "active", "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d", "version": 1, "description": null }, "framework": null }, "subkind": "headline", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.246+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "f44fff30-4cfd-4931-a303-6be3aaebb997", "parentComponentId": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "thumbSrc": "https://imgproxy.kitesheet.com/rfmm4fg6jvrc4EdI81zKrQHQix6_qgp41AaGHgOyfOQ/rs:fit:480:480:0/q:78/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy8zMDAzYTk0ZmEzYmU3YzhmMmZmMGZiYWM1YTU0YjI2ZS9wMDAxLmpwZw", "imagePathAlt": "https://imgproxy.kitesheet.com/DIUxnAWV662n3gDcFjBR4btXIrgIhl-uWyMTqm-E9ws/rs:fit:1200:1200:0/q:82/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy8zMDAzYTk0ZmEzYmU3YzhmMmZmMGZiYWM1YTU0YjI2ZS9wMDAxLnBuZw", "thumbSrcAlt": "https://imgproxy.kitesheet.com/fuc9ldklVmDKHmHtXLiCldlzu3PbOCyJ1qELgnzpnnE/rs:fit:480:480:0/q:78/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy8zMDAzYTk0ZmEzYmU3YzhmMmZmMGZiYWM1YTU0YjI2ZS9wMDAxLnBuZw" }, { "page": 2, "type": "setup", "function": "other", "rawType": "disclaimer", "block": null, "metadata": { "slideType": "disclaimer", "slideTypeCanon": { "name": "Disclaimer", "slug": "disclaimer", "status": "active", "canonId": "019de52d-0801-727b-b98a-5ed095aeee78", "version": 1, "description": null }, "function": "other", "functionCanon": { "name": "Other (fallback)", "slug": "other", "status": "active", "canonId": "019de52d-15e1-75bc-99dc-07732380e2ce", "version": 1, "description": null }, "density": "sparse", "densityScore": 20, "componentCount": 2, "textChars": 289, "nDataPoints": 0, "notes": null, "elementsJson": null, "confidence": 1, "extraction": { "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "at": "2026-05-02 12:20:38.053+00", "seconds": 2.08, "promptVersion": "v2-canon-conditioned" } }, "links": { "slide": "/slides/019de073-e8d5-735f-8ffd-8a5102406a96/2", "deck": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96", "deckAnchor": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96#slide-2", "deckJson": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96.json" }, "components": [ { "bbox": { "h": 0.685, "w": 0.848, "x": 0.076, "y": 0.175 }, "kind": "disclaimer", "text": "This presentation contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 and Canadian securities laws. All statements that are not historical facts are hereby identified as forward-looking statements...", "attrs": null, "canon": { "kind": { "name": "Disclaimer", "slug": "disclaimer", "status": "active", "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc", "version": 1, "description": "Legal/cautionary text that occupies most of the body of its slide." }, "tool": null, "subkind": null, "framework": null }, "subkind": null, "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.053+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "42618e02-8b4c-4ed4-b6b4-fe20094b6464", "parentComponentId": null }, { "bbox": { "h": 0.065, "w": 0.498, "x": 0.076, "y": 0.065 }, "kind": "title", "text": "Forward-Looking Statements", "attrs": null, "canon": { "kind": { "name": "Title", "slug": "title", "status": "active", "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4", "version": 1, "description": "Slide title or headline." }, "tool": null, "subkind": { "name": "Headline", "slug": "headline", "status": "active", "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d", "version": 1, "description": null }, "framework": null }, "subkind": "headline", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.053+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "6f074f77-d167-41b2-99d7-9c68744d3474", "parentComponentId": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "locked": true }, { "page": 3, "type": "analysis", "title": "Includes cohort definitions and a detailed baseline characteristics table for multiple cohorts.", "function": "analyze_data", "rawType": "appendix_data", "block": null, "metadata": { "slideType": "appendix_data", "slideTypeCanon": { "name": "Appendix data", "slug": "appendix_data", "status": "active", "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd", "version": 1, "description": null }, "function": "analyze_data", "functionCanon": { "name": "Analyze data", "slug": "analyze_data", "status": "active", "canonId": "019de52d-1590-7413-8c82-cc218cff40b4", "version": 1, "description": null }, "density": "dense", "densityScore": 54, "componentCount": 5, "textChars": 281, "nDataPoints": 100, "notes": "Includes cohort definitions and a detailed baseline characteristics table for multiple cohorts.", "elementsJson": null, "confidence": 1, "extraction": { "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "at": "2026-05-02 12:20:38.512+00", "seconds": 2.509, "promptVersion": "v2-canon-conditioned" } }, "links": { "slide": "/slides/019de073-e8d5-735f-8ffd-8a5102406a96/3", "deck": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96", "deckAnchor": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96#slide-3", "deckJson": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96.json" }, "components": [ { "bbox": { "h": 0.6, "w": 0.15, "x": 0.3, "y": 0.25 }, "kind": "diagram", "text": "Cohort list E, F, G, I, J, K", "attrs": null, "canon": { "kind": { "name": "Diagram", "slug": "diagram", "status": "active", "canonId": "019de52c-f9f0-734a-81de-15382ff28c65", "version": 1, "description": "Schematic or relational diagram." }, "tool": null, "subkind": { "name": "Process flow", "slug": "process", "status": "active", "canonId": "019de52d-039c-718f-ad3a-efe9c4b3c838", "version": 1, "description": null }, "framework": null }, "subkind": "process", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.512+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "0fe1ce8f-1dc4-49c6-a60b-0d8b416c90b7", "parentComponentId": null }, { "bbox": { "h": 0.2, "w": 0.22, "x": 0.04, "y": 0.22 }, "kind": "paragraph", "text": "Part 1 & 2: Single-ascending dose. Robust HBsAg and HBV DNA declines in HBV DNA+ patients with AB-729 monotherapy (90mg single-dose)", "attrs": null, "canon": { "kind": { "name": "Paragraph", "slug": "paragraph", "status": "active", "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4", "version": 1, "description": "Single prose block in the body of a slide." }, "tool": null, "subkind": { "name": "Paragraph", "slug": "paragraph", "status": "active", "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433", "version": 1, "description": null }, "framework": null }, "subkind": "paragraph", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.512+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "f311484f-ef90-4e4e-88da-d51a244eec2e", "parentComponentId": null }, { "bbox": { "h": 0.03, "w": 0.15, "x": 0.73, "y": 0.95 }, "kind": "source-note", "text": "Data presented at AASLD 2022", "attrs": null, "canon": { "kind": { "name": "Source note", "slug": "source-note", "status": "active", "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948", "version": 1, "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered." }, "tool": null, "subkind": null, "framework": null }, "subkind": null, "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.512+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "209dd48f-e0fb-42e1-8925-a44fda35a6e1", "parentComponentId": null }, { "bbox": { "h": 0.5, "w": 0.5, "x": 0.47, "y": 0.27 }, "kind": "table", "text": "Baseline Demographics and Clinical Characteristics table", "attrs": null, "canon": { "kind": { "name": "Table", "slug": "table", "status": "active", "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28", "version": 1, "description": "Tabular data layout." }, "tool": null, "subkind": { "name": "Data table", "slug": "data", "status": "active", "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569", "version": 1, "description": null }, "framework": null }, "subkind": "data", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.512+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "5d9d1cd2-63ca-4896-ae07-7a51b37cfdc9", "parentComponentId": null }, { "bbox": { "h": 0.06, "w": 0.5, "x": 0.06, "y": 0.04 }, "kind": "title", "text": "AB-729-001 Phase 1a/1b Clinical Trial", "attrs": null, "canon": { "kind": { "name": "Title", "slug": "title", "status": "active", "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4", "version": 1, "description": "Slide title or headline." }, "tool": null, "subkind": { "name": "Headline", "slug": "headline", "status": "active", "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d", "version": 1, "description": null }, "framework": null }, "subkind": "headline", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:38.512+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "5864ac3d-6ab9-4fe1-9199-e0d03d4e6c28", "parentComponentId": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "locked": true }, { "page": 4, "type": "analysis", "title": "Data presented at AASLD 2022. Includes footnote regarding LLOQ and specific cohort exclusions.", "function": "analyze_data", "rawType": "kpi_overview", "block": null, "metadata": { "slideType": "kpi_overview", "slideTypeCanon": { "name": "KPI overview (contrarian)", "slug": "kpi_overview", "status": "active", "canonId": "019de52d-11d5-7328-b1d1-5368a03e7796", "version": 1, "description": null }, "function": "analyze_data", "functionCanon": { "name": "Analyze data", "slug": "analyze_data", "status": "active", "canonId": "019de52d-1590-7413-8c82-cc218cff40b4", "version": 1, "description": null }, "density": "dense", "densityScore": 58, "componentCount": 4, "textChars": 615, "nDataPoints": 84, "notes": "Data presented at AASLD 2022. Includes footnote regarding LLOQ and specific cohort exclusions.", "elementsJson": null, "confidence": 1, "extraction": { "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "at": "2026-05-02 12:20:39.489+00", "seconds": 3.29, "promptVersion": "v2-canon-conditioned" } }, "links": { "slide": "/slides/019de073-e8d5-735f-8ffd-8a5102406a96/4", "deck": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96", "deckAnchor": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96#slide-4", "deckJson": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96.json" }, "components": [ { "bbox": { "h": 0.3, "w": 0.3, "x": 0.67, "y": 0.365 }, "kind": "list", "text": "Mean declines in HBsAg on treatment and post treatment continue to be comparable across cohorts. Results to date from a dedicated HBeAg+ cohort (Cohort K) further support preliminary observations suggesting that baseline HBeAg status has no effect on response", "attrs": null, "canon": { "kind": { "name": "List", "slug": "list", "status": "active", "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2", "version": 1, "description": "Bullet or numbered list." }, "tool": null, "subkind": { "name": "Bullet list", "slug": "bullet", "status": "active", "canonId": "019de52c-fc98-7169-a083-5cab805076ca", "version": 1, "description": null }, "framework": null }, "subkind": "bullet", "groupRole": null, "confidence": null, "extraction": { "at": "2026-05-02 12:20:39.489+00", "model": "google/gemini-3.1-flash-lite-preview-20260303", "runId": null, "seconds": null, "promptVersion": null }, "componentId": "c8a4ae88-a7b1-4b1b-99fe-ff2f805638af", "parentComponentId": null }, { "bbox": { "h": 0.06, "w": 0.45, "x": 0.19, "y": 0.88 }, "kind": "source-note", "text": "Data shown as mean (SE) log10 IU/mL; HBsAg LLOQ = 0.07 IU/mL,