{
  "schemaVersion": "deck-intelligence.v1",
  "id": "019de073-9947-75c9-ab6d-01a31b39af7e",
  "slug": "f6e6ee19ba9d775ca06fb17f83eb8b7f",
  "title": "Third Harmonic Bio | IPO Presentation Deck | 24 slides",
  "subtitle": "Third Harmonic Bio · 2022-09",
  "author": "Third Harmonic Bio",
  "date": "2022-09-01 00:00:00",
  "pageCount": 24,
  "kind": "pitchdeck",
  "orientation": "landscape",
  "aspectRatio": 1.7761332,
  "document": {
    "id": "019de073-9947-75c9-ab6d-01a31b39af7e",
    "slug": "f6e6ee19ba9d775ca06fb17f83eb8b7f",
    "title": "Third Harmonic Bio | IPO Presentation Deck | 24 slides",
    "rawTitle": "Third Harmonic Bio | IPO Presentation Deck | 24 slides",
    "authorId": "third-harmonic-bio",
    "authorName": "Third Harmonic Bio",
    "authorDisplay": "Third Harmonic Bio",
    "kind": {
      "slug": "pitchdeck",
      "label": "Pitch deck"
    },
    "sourceType": {
      "slug": "investment_bank",
      "label": "Investment bank"
    },
    "fileName": "2022-09__third-harmonic-bio__ipo__f6e6ee19.pdf",
    "sourceUrl": "https://www.slidebook.io/company/third-harmonic-bio/presentation/f6e6ee19ba9d775ca06fb17f83eb8b7f/",
    "sourceDate": "2022-09-15 00:00:00",
    "presentationDate": "2022-09-01 00:00:00",
    "ingestedAt": "2026-04-30 22:12:45.612826+00",
    "status": "ready",
    "pageCount": 24,
    "orientation": "landscape",
    "aspectRatio": 1.7761332,
    "targetCompany": null,
    "targetTicker": null,
    "metadata": {
      "corpus": "slidebook",
      "industry": "biotechnology",
      "local_root": "/Users/miguelsuredasuau/Desktop/lalalalla/_scrape/slidebook/decks/2022-09__third-harmonic-bio__ipo__f6e6ee19",
      "image_width": 1920,
      "image_format": "jpg",
      "deck_type_raw": "IPO Presentation Deck",
      "deck_type_slug": null,
      "source_url_pattern": "https://www.slidebook.io/company/{company_slug}/presentation/{deck_id}/"
    }
  },
  "coverage": {
    "pageCount": 24,
    "pagesIndexed": 24,
    "pagesWithImages": 24,
    "pagesWithMetadata": 24,
    "imageCoveragePct": 100,
    "metadataCoveragePct": 100,
    "componentCount": 122,
    "chartCount": 12,
    "metricSlides": 0,
    "toolMatches": 15,
    "documentToolMatches": 0,
    "frameworkMatches": 4,
    "arcMatches": 1,
    "beatMatches": 3,
    "loopMatches": 2,
    "patternMatches": 0,
    "storymakersMatch": false,
    "scoreAvailable": false,
    "reviewAvailable": false,
    "activistThesisAvailable": false,
    "pitchdeckMetadataAvailable": false,
    "pitchdeckProfileAvailable": false
  },
  "blocks": [],
  "matches": {
    "arcs": [
      {
        "arc": {
          "name": "The Sequoia Pitch",
          "slug": "sequoia-pitch",
          "status": "active",
          "bestFor": "Investor pitches, Series A/B, board presentations",
          "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
          "version": 1,
          "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
          "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
          "description": null,
          "familyLabel": null,
          "categoryName": "Strategy & Business",
          "categorySlug": "strategy-business"
        },
        "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
        "evidence": "The deck follows a similar structure to the Sequoia Pitch, with sections on problem, solution, market size, product, and team.",
        "isPrimary": true,
        "confidence": 0.8,
        "extraction": {
          "at": "2026-07-16 22:26:33.470255+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": "doc-narrative-v1"
        }
      }
    ],
    "beats": [
      {
        "to": 6,
        "arc": {
          "name": "The Sequoia Pitch",
          "slug": "sequoia-pitch",
          "status": "active",
          "bestFor": "Investor pitches, Series A/B, board presentations",
          "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
          "version": 1,
          "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
          "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
          "description": null,
          "familyLabel": null,
          "categoryName": "Strategy & Business",
          "categorySlug": "strategy-business"
        },
        "from": 5,
        "name": "Problem",
        "beatId": "d1a3d44c-6014-43c9-929f-a12d0af45eec",
        "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
        "beatType": {
          "name": "Problem",
          "slug": "sequoia-pitch-problem",
          "status": "active",
          "canonId": "019dd9b8-1ed4-767b-8e05-40e733bd2311",
          "version": 1,
          "description": null
        },
        "evidence": "The deck presents the problem statement on pages 5 and 6, highlighting the role of mast cells in allergy and inflammation.",
        "position": 0,
        "isPrimaryArc": true,
        "parentBeatType": {
          "name": "Complication",
          "slug": "complication",
          "status": "active",
          "canonId": "019dd9b8-0275-7709-b2d6-4f77c3fc7579",
          "version": 1,
          "description": "The point in the narrative where the audience should feel discomfort. Required for argumentative arcs."
        },
        "alignedBlockIds": null,
        "matchConfidence": 0.8
      },
      {
        "to": 8,
        "arc": {
          "name": "The Sequoia Pitch",
          "slug": "sequoia-pitch",
          "status": "active",
          "bestFor": "Investor pitches, Series A/B, board presentations",
          "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
          "version": 1,
          "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
          "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
          "description": null,
          "familyLabel": null,
          "categoryName": "Strategy & Business",
          "categorySlug": "strategy-business"
        },
        "from": 7,
        "name": "Solution",
        "beatId": "56e9f7b6-e6ea-4b9d-b393-88a0ff25d5c3",
        "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
        "beatType": {
          "name": "Solution",
          "slug": "sequoia-pitch-solution",
          "status": "active",
          "canonId": "019dd9b8-1fb1-71d9-a260-07738d7f9c2f",
          "version": 1,
          "description": null
        },
        "evidence": "The deck presents the solution on pages 7 and 8, introducing THB001 as a highly selective oral wild-type KIT inhibitor.",
        "position": 1,
        "isPrimaryArc": true,
        "parentBeatType": {
          "name": "Turn",
          "slug": "turn",
          "status": "active",
          "canonId": "019dd9b8-0396-702b-ac2f-9901f8dd8b54",
          "version": 1,
          "description": "The pivot — solution proposed, catalyst introduced, decision made. Common (15/20 arcs) but not universal: Triple-take, AIDA, PAS, Voyage-return and Pixar substitute it with a strong reflection or development beat."
        },
        "alignedBlockIds": null,
        "matchConfidence": 0.8
      },
      {
        "to": 21,
        "arc": {
          "name": "The Sequoia Pitch",
          "slug": "sequoia-pitch",
          "status": "active",
          "bestFor": "Investor pitches, Series A/B, board presentations",
          "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
          "version": 1,
          "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
          "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
          "description": null,
          "familyLabel": null,
          "categoryName": "Strategy & Business",
          "categorySlug": "strategy-business"
        },
        "from": 20,
        "name": "Market Size",
        "beatId": "3071eeb1-d844-41d8-a60d-a94623bcd39f",
        "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
        "beatType": {
          "name": "Market Size",
          "slug": "sequoia-pitch-market-size",
          "status": "active",
          "canonId": "019dd9b8-20e6-729c-bc28-05442906d032",
          "version": 1,
          "description": null
        },
        "evidence": "The deck presents an overview of the market size on pages 20 and 21, discussing chronic urticaria and severe asthma.",
        "position": 2,
        "isPrimaryArc": true,
        "parentBeatType": {
          "name": "Evidence",
          "slug": "evidence",
          "status": "active",
          "canonId": "019dd9b8-03f9-772a-b84a-4f07b415b77a",
          "version": 1,
          "description": "A dedicated proof beat exists in only ~4 arcs (Gambit, Sequoia, AIDA, Monroes). Other arcs embed evidence inline within development."
        },
        "alignedBlockIds": null,
        "matchConfidence": 0.8
      }
    ],
    "loops": [
      {
        "to": 21,
        "from": 5,
        "loop": {
          "name": "27_cost_of_inaction",
          "slug": "27-cost-of-inaction",
          "status": "active",
          "bestFor": "Urgent budget requests, compliance, risk mitigation",
          "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
          "version": 1,
          "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
          "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
          "description": "Quantify what happens if the audience does nothing",
          "familyLabel": null,
          "categoryName": "Urgency",
          "categorySlug": "urgency"
        },
        "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
        "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
        "position": 0,
        "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-16 22:26:33.613276+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": "doc-narrative-v1"
        }
      },
      {
        "to": 24,
        "from": 18,
        "loop": {
          "name": "47_quick_win_big_bet",
          "slug": "47-quick-win-big-bet",
          "status": "active",
          "bestFor": "Transformation planning, 100-day plans, resource allocation",
          "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
          "version": 1,
          "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
          "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
          "description": "Separate initiatives into immediate wins and longer-term strategic bets",
          "familyLabel": null,
          "categoryName": "Consulting Framework",
          "categorySlug": "consulting-framework"
        },
        "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
        "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
        "position": 1,
        "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
        "confidence": 0.6,
        "extraction": {
          "at": "2026-07-16 22:26:33.648143+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": "doc-narrative-v1"
        }
      }
    ],
    "tools": [
      {
        "tool": {
          "name": "Slide recipe: Cover",
          "slug": "cover-slide",
          "status": "active",
          "bestFor": null,
          "canonId": "019df269-2a08-767d-9128-e7431e6fe8a3",
          "version": 1,
          "bodyDocId": "019df269-29e5-7738-b5fa-6892e5dc8e65",
          "description": "The first ten seconds. Build it deliberately.",
          "familyLabel": "slide-recipe",
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "designer",
        "layer": "slide",
        "agents": [
          "designer"
        ],
        "matchId": "2aa96d03-ea44-4ecf-9793-763928516a1d",
        "evidence": "type: cover",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-07-17 00:10:59.937121+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 1,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Table data",
          "slug": "table-data",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
          "version": 1,
          "bodyDocId": null,
          "description": "Tabular layouts of structured data.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "9ba38c78-27ed-4466-90cc-553591387c10",
        "evidence": "table/data: Lock-up: 180 days for the Company, directors, officers, affiliates, and substantially all pre-IPO securityholders",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:11:00.074623+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 3,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Executive summary",
          "slug": "executive-summary",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4b63-72d5-9734-da757d91ca61",
          "version": 1,
          "bodyDocId": null,
          "description": "A condensed view of the entire argument on a single slide / block.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "0c2ec08c-1a67-4550-a16c-bcf885994b2a",
        "evidence": "type: executive_summary",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-07-17 00:11:00.170542+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 4,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Problem Statement Canvas",
          "slug": "problem-statement-canvas",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
          "version": 1,
          "bodyDocId": null,
          "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
          "familyLabel": null,
          "categoryName": "Block",
          "categorySlug": "block"
        },
        "agent": "Architect",
        "layer": "slide",
        "agents": [
          "Architect"
        ],
        "matchId": "4db33087-ee40-4a06-a4a2-03f71562bbfb",
        "evidence": "paragraph/paragraph: Millions of patients living with severe allergy and other mast cell-mediated diseases; high residual need despite multiple approved products",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.5,
        "extraction": {
          "at": "2026-07-17 00:11:00.220443+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 4,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "List presentation",
          "slug": "list-presentation",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4ef7-777d-ba68-9074c2b3bcf1",
          "version": 1,
          "bodyDocId": null,
          "description": "Bulleted, numbered, or checklist enumerations.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "15bf74a3-ef6a-4de3-9675-7d8dc34e4940",
        "evidence": "list/bullet: Many Mediators: Pre-formed Mediators, Newly Synthesized Mediators, Lymphocyte ligands",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:11:00.459604+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 5,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Chart Selection Guide",
          "slug": "chart-selection-guide",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
          "version": 1,
          "bodyDocId": null,
          "description": "Choosing the right chart type for your data and message",
          "familyLabel": null,
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "Designer",
        "layer": "slide",
        "agents": [
          "Designer"
        ],
        "matchId": "a1cc8620-2154-4f28-a0cf-742c2b8af719",
        "evidence": "chart/line: Barzovolimab Phase 1b Chronic Spontaneous Urticaria Interim Data",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:11:00.78451+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 6,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Table data",
          "slug": "table-data",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
          "version": 1,
          "bodyDocId": null,
          "description": "Tabular layouts of structured data.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "353ff090-edc8-4601-a91c-640a0f6f4d83",
        "evidence": "table/data: Inhibition of Kinases by THB001 in Ba/F3 Assays: KIT (0.02, -), CSF1R (0.95, 48), PDGFR-beta (2.11, 106), PDGFR-alpha (3.95, 198), FLT3 (>10.7, >535)",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:11:00.911833+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 7,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Chartjunk Elimination",
          "slug": "chartjunk-elimination",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-b49e-7453-ab01-b60f338eeda1",
          "version": 1,
          "bodyDocId": null,
          "description": "Remove decorative elements that don't convey data: 3D effects, shadows, unnecessary gridlines",
          "familyLabel": null,
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "Designer",
        "layer": "slide",
        "agents": [
          "Designer"
        ],
        "matchId": "be858f9e-cde1-44b4-b0cf-a235e2269681",
        "evidence": "The line chart for THB001 Multiple Dose PK (14 days) appears to effectively communicate data without unnecessary elements.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:58.99065+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 9,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Table data",
          "slug": "table-data",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
          "version": 1,
          "bodyDocId": null,
          "description": "Tabular layouts of structured data.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "ab0ce22a-eb97-49d5-a031-f38b2ed19eef",
        "evidence": "The MAD Treatment Emergent Adverse Events table clearly presents data in a structured format.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-07-17 00:10:59.071333+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 10,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Chart Selection Guide",
          "slug": "chart-selection-guide",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
          "version": 1,
          "bodyDocId": null,
          "description": "Choosing the right chart type for your data and message",
          "familyLabel": null,
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "Designer",
        "layer": "slide",
        "agents": [
          "Designer"
        ],
        "matchId": "8acdb670-eda8-4d94-9c03-b80beb3b7925",
        "evidence": "The line chart for Neutrophils (10^9/L) over Study Day effectively displays data for comparison across different treatment groups.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:59.158774+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 11,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Table data",
          "slug": "table-data",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
          "version": 1,
          "bodyDocId": null,
          "description": "Tabular layouts of structured data.",
          "familyLabel": null,
          "categoryName": null,
          "categorySlug": null
        },
        "agent": null,
        "layer": "slide",
        "agents": null,
        "matchId": "c1b7c037-94bb-4fe8-97ef-c63f5ff00669",
        "evidence": "The THB001 and Barzovolimab hematology data tables present comparative data in a clear and organized manner.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-07-17 00:10:59.241811+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 12,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": "common",
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Chartjunk Elimination",
          "slug": "chartjunk-elimination",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-b49e-7453-ab01-b60f338eeda1",
          "version": 1,
          "bodyDocId": null,
          "description": "Remove decorative elements that don't convey data: 3D effects, shadows, unnecessary gridlines",
          "familyLabel": null,
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "Designer",
        "layer": "slide",
        "agents": [
          "Designer"
        ],
        "matchId": "46feb3db-b565-4970-a2d0-5160647e31af",
        "evidence": "The line charts for Serum Tryptase Normalized to Baseline Over Time and Mean Absolute Serum Tryptase Over Time effectively communicate data without unnecessary elements.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:59.328505+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 13,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Chart Selection Guide",
          "slug": "chart-selection-guide",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
          "version": 1,
          "bodyDocId": null,
          "description": "Choosing the right chart type for your data and message",
          "familyLabel": null,
          "categoryName": "Slide",
          "categorySlug": "slide"
        },
        "agent": "Designer",
        "layer": "slide",
        "agents": [
          "Designer"
        ],
        "matchId": "c499b99d-efdb-4242-acac-d1711df4afd6",
        "evidence": "The line chart for THB001 Interim Human BioA Data (200mg crossover) effectively displays data to support the ~3x increase in exposure claim.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:59.457291+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 15,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Problem Statement Canvas",
          "slug": "problem-statement-canvas",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
          "version": 1,
          "bodyDocId": null,
          "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
          "familyLabel": null,
          "categoryName": "Block",
          "categorySlug": "block"
        },
        "agent": "Architect",
        "layer": "slide",
        "agents": [
          "Architect"
        ],
        "matchId": "0eb71c1a-ae3e-4aa6-8482-8538df98172f",
        "evidence": "The Chronic Urticaria Disease Overview effectively frames the problem with bulleted points and supporting data.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:59.709791+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 20,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      },
      {
        "tool": {
          "name": "Problem Statement Canvas",
          "slug": "problem-statement-canvas",
          "status": "active",
          "bestFor": null,
          "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
          "version": 1,
          "bodyDocId": null,
          "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
          "familyLabel": null,
          "categoryName": "Block",
          "categorySlug": "block"
        },
        "agent": "Architect",
        "layer": "slide",
        "agents": [
          "Architect"
        ],
        "matchId": "8e4611e9-b1cc-4e68-af16-eff831bb4a51",
        "evidence": "The slide presents a problem statement with disease overview, limited treatment options, and statistics, which matches the problem statement canvas.",
        "pageRefs": null,
        "priority": null,
        "whenToUse": null,
        "confidence": 0.7,
        "extraction": {
          "at": "2026-07-17 00:10:59.207447+00",
          "model": "or:meta-llama/llama-4-scout",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 21,
        "whyItWorks": null,
        "antipattern": null,
        "cardinality": null,
        "narrativePurpose": null
      }
    ],
    "frameworks": [
      {
        "matchId": "fc0ee956-f6b7-4497-b4f6-0bad8c2d8117",
        "evidence": "Central mast cell with inputs on left and outputs on right",
        "framework": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-05-02 12:28:18.274+00",
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 5,
        "frameworkName": "hub-spoke"
      },
      {
        "matchId": "ed4f3c74-bca5-4350-8584-a79de5571aa8",
        "evidence": "Standard pharmaceutical industry representation of Phase 1 study arms",
        "framework": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-05-02 12:28:18.419+00",
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 8,
        "frameworkName": "clinical-trial-design"
      },
      {
        "matchId": "18db4989-fb48-4b98-b91e-3d26fb65b58b",
        "evidence": "Schematic representation of patient cohorts, dosing, and follow-up",
        "framework": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-05-02 12:28:19.796+00",
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 14,
        "frameworkName": "clinical-trial-design"
      },
      {
        "matchId": "e449a310-7896-43dc-b21a-9c71161318a0",
        "evidence": "Timeline visualization of clinical milestones over time",
        "framework": null,
        "confidence": 0.9,
        "extraction": {
          "at": "2026-05-02 12:28:20.586+00",
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "seconds": null,
          "promptVersion": null
        },
        "pageNumber": 18,
        "frameworkName": "gantt-chart"
      }
    ],
    "patterns": []
  },
  "storymakers": null,
  "score": null,
  "review": null,
  "activistThesis": null,
  "pitchdeck": {
    "metadata": null,
    "profile": null
  },
  "slides": [
    {
      "page": 1,
      "type": "setup",
      "function": "front_matter",
      "imagePath": "https://imgproxy.kitesheet.com/sKrd1R_7JTzChvedVonQu7evsEFsYAzx2SyTGNvFl1A/rs:fit:1200:1200:0/q:82/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy9mNmU2ZWUxOWJhOWQ3NzVjYTA2ZmIxN2Y4M2ViOGI3Zi9wMDAxLmpwZw",
      "rawType": "cover",
      "block": null,
      "metadata": {
        "slideType": "cover",
        "slideTypeCanon": {
          "name": "Cover",
          "slug": "cover",
          "status": "active",
          "canonId": "019de52d-05f2-729d-9f93-e0504f0a2410",
          "version": 1,
          "description": null
        },
        "function": "front_matter",
        "functionCanon": {
          "name": "Front matter",
          "slug": "front_matter",
          "status": "active",
          "canonId": "019de52d-133d-73f0-9e26-201eda96b098",
          "version": 1,
          "description": null
        },
        "density": "sparse",
        "densityScore": 24,
        "componentCount": 4,
        "textChars": 144,
        "nDataPoints": 0,
        "notes": null,
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:16.901+00",
          "seconds": 2.309,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/1",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-1",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.02,
            "w": 0.15,
            "x": 0.04,
            "y": 0.95
          },
          "kind": "disclaimer",
          "text": "©2022 THIRD HARMONIC BIO",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Disclaimer",
              "slug": "disclaimer",
              "status": "active",
              "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc",
              "version": 1,
              "description": "Legal/cautionary text that occupies most of the body of its slide."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:16.901+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3beb250e-1377-4db8-af00-32a8a4e2e55b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.17,
            "w": 0.245,
            "x": 0.654,
            "y": 0.415
          },
          "kind": "image",
          "text": "Third Harmonic Bio",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Logo",
              "slug": "logo",
              "status": "active",
              "canonId": "019de52c-fdaf-743d-94c4-d7c6a0e55302",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "logo",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:16.901+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0d9a755a-44cf-4a20-8f5a-6479ab551f3c",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.3,
            "x": 0.04,
            "y": 0.9
          },
          "kind": "paragraph",
          "text": "ROADSHOW PRESENTATION | SEPTEMBER 2022",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:16.901+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4f0e1abd-1172-482b-898e-a4b131f6ca12",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.45,
            "x": 0.04,
            "y": 0.38
          },
          "kind": "title",
          "text": "Advancing the Next Wave of Medicine for Allergy and Inflammation",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:16.901+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0774083a-12f7-4fbe-bf69-5f3ba7dc46a4",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Slide recipe: Cover",
            "slug": "cover-slide",
            "status": "active",
            "bestFor": null,
            "canonId": "019df269-2a08-767d-9128-e7431e6fe8a3",
            "version": 1,
            "bodyDocId": "019df269-29e5-7738-b5fa-6892e5dc8e65",
            "description": "The first ten seconds. Build it deliberately.",
            "familyLabel": "slide-recipe",
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "designer",
          "layer": "slide",
          "agents": [
            "designer"
          ],
          "matchId": "2aa96d03-ea44-4ecf-9793-763928516a1d",
          "evidence": "type: cover",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-07-17 00:10:59.937121+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 1,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [],
      "thumbSrc": "https://imgproxy.kitesheet.com/_xro5XQOtZIJVPbSsoZ_yHahwgPuXg7RdRr85yuL59A/rs:fit:480:480:0/q:78/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy9mNmU2ZWUxOWJhOWQ3NzVjYTA2ZmIxN2Y4M2ViOGI3Zi9wMDAxLmpwZw",
      "imagePathAlt": "https://imgproxy.kitesheet.com/2KcYVD8em9FPiAcGQVnk-SRQ2bz1e-hUpqZncW2RTXQ/rs:fit:1200:1200:0/q:82/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy9mNmU2ZWUxOWJhOWQ3NzVjYTA2ZmIxN2Y4M2ViOGI3Zi9wMDAxLnBuZw",
      "thumbSrcAlt": "https://imgproxy.kitesheet.com/gWw_IK3mnCkunEelNVOq2Oi8gxk4c21ZwjFs7IB5QsA/rs:fit:480:480:0/q:78/f:webp/czM6Ly9raXRlc2hlZXQvY29ycHVzL3NsaWRlcy9mNmU2ZWUxOWJhOWQ3NzVjYTA2ZmIxN2Y4M2ViOGI3Zi9wMDAxLnBuZw"
    },
    {
      "page": 2,
      "type": "setup",
      "function": "other",
      "rawType": "appendix_disclosure",
      "block": null,
      "metadata": {
        "slideType": "appendix_disclosure",
        "slideTypeCanon": {
          "name": "Appendix disclosure",
          "slug": "appendix_disclosure",
          "status": "active",
          "canonId": "019de52d-07b2-7549-8e8b-932a19f6e616",
          "version": 1,
          "description": null
        },
        "function": "other",
        "functionCanon": {
          "name": "Other (fallback)",
          "slug": "other",
          "status": "active",
          "canonId": "019de52d-15e1-75bc-99dc-07732380e2ce",
          "version": 1,
          "description": null
        },
        "density": "sparse",
        "densityScore": 20,
        "componentCount": 2,
        "textChars": 286,
        "nDataPoints": 0,
        "notes": null,
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:17.043+00",
          "seconds": 2.23,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/2",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-2",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.75,
            "w": 0.9,
            "x": 0.05,
            "y": 0.15
          },
          "kind": "disclaimer",
          "text": "This presentation contains forward-looking statements. Any statements made in this presentation that are not statements of historical fact, including statements about our beliefs and expectations, are forward-looking statements and should be evaluated as such.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Disclaimer",
              "slug": "disclaimer",
              "status": "active",
              "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc",
              "version": 1,
              "description": "Legal/cautionary text that occupies most of the body of its slide."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:17.043+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a9e5081f-adfd-4bfe-9c9d-7231d1f336ba",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.35,
            "x": 0.05,
            "y": 0.05
          },
          "kind": "title",
          "text": "Forward Looking Statements",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:17.043+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "466b7e96-49ca-4b31-aa0f-28740b3bdffe",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [],
      "locked": true
    },
    {
      "page": 3,
      "type": "setup",
      "function": "summarize",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "summarize",
        "functionCanon": {
          "name": "Summarize",
          "slug": "summarize",
          "status": "active",
          "canonId": "019de52d-1541-704f-b86f-bf7b75056373",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 58,
        "componentCount": 4,
        "textChars": 878,
        "nDataPoints": 4,
        "notes": null,
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:18.173+00",
          "seconds": 2.994,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/3",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-3",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.25,
            "w": 0.74,
            "x": 0.224,
            "y": 0.47
          },
          "kind": "list",
          "text": "Use of Proceeds: The Company currently intends to use the net proceeds from this offering, together with its existing cash and cash equivalents, as follows: To advance the continued clinical development of THB001 for the treatment of urticaria... To advance the continued clinical development of THB001 in additional indications... The remainder for potential expansion of the pipeline...",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.173+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4e792fcb-560b-4ec6-a370-62829fa35f84",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.928,
            "x": 0.036,
            "y": 0.72
          },
          "kind": "table",
          "text": "Lock-up: 180 days for the Company, directors, officers, affiliates, and substantially all pre-IPO securityholders Bookrunners: Morgan Stanley, Jefferies, Cowen Co-Manager: LifeSci Capital Expected Pricing: Wednesday September 14, 2022 (Post-Close)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.173+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "6efc2b3b-9dc5-4e71-9c3b-a26d193f3adf",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.32,
            "w": 0.928,
            "x": 0.036,
            "y": 0.15
          },
          "kind": "table",
          "text": "Issuer: Third Harmonic Bio, Inc. Ticker / Exchange: THRD / Nasdaq Shares Offered: 9,000,000 (100% Primary) Filing Range: $16.00 – $18.00 per share Estimated Gross Proceeds: $153,000,000 Over-Allotment Option: 15% (100% Primary)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.173+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b00a18d0-dea7-4471-ad7f-bc96c46bfe14",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.038,
            "w": 0.248,
            "x": 0.036,
            "y": 0.065
          },
          "kind": "title",
          "text": "Offering Summary",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.173+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3fecc9ff-7aa0-4518-aba2-e97c1ebdede3",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Table data",
            "slug": "table-data",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
            "version": 1,
            "bodyDocId": null,
            "description": "Tabular layouts of structured data.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "9ba38c78-27ed-4466-90cc-553591387c10",
          "evidence": "table/data: Lock-up: 180 days for the Company, directors, officers, affiliates, and substantially all pre-IPO securityholders",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:11:00.074623+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 3,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [],
      "locked": true
    },
    {
      "page": 4,
      "type": "setup",
      "function": "summarize",
      "rawType": "executive_summary",
      "block": null,
      "metadata": {
        "slideType": "executive_summary",
        "slideTypeCanon": {
          "name": "Executive summary",
          "slug": "executive_summary",
          "status": "active",
          "canonId": "019de52d-06be-73ff-81b3-f99fe7f0025e",
          "version": 1,
          "description": null
        },
        "function": "summarize",
        "functionCanon": {
          "name": "Summarize",
          "slug": "summarize",
          "status": "active",
          "canonId": "019de52d-1541-704f-b86f-bf7b75056373",
          "version": 1,
          "description": null
        },
        "density": "overcrowded",
        "densityScore": 83,
        "componentCount": 13,
        "textChars": 729,
        "nDataPoints": 0,
        "notes": null,
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.31+00",
          "seconds": 4.128,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/4",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-4",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.35,
            "w": 0.22,
            "x": 0.75,
            "y": 0.345
          },
          "kind": "chart",
          "text": null,
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Donut chart",
              "slug": "donut",
              "status": "active",
              "canonId": "019de52d-0006-752c-9528-0fef476b8004",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "donut",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "6056c065-98ec-49c1-969f-ae72b2176aa8",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.22,
            "x": 0.27,
            "y": 0.345
          },
          "kind": "image",
          "text": null,
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Illustration",
              "slug": "illustration",
              "status": "active",
              "canonId": "019de52c-fe76-7772-a5ac-c0b7294d7615",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "illustration",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0d47539e-67a2-49de-a649-2825ec9a7483",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.22,
            "x": 0.51,
            "y": 0.345
          },
          "kind": "image",
          "text": null,
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Illustration",
              "slug": "illustration",
              "status": "active",
              "canonId": "019de52c-fe76-7772-a5ac-c0b7294d7615",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "illustration",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "51065d46-27ac-4fae-a92d-ccd1faea41ab",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.22,
            "x": 0.03,
            "y": 0.345
          },
          "kind": "image",
          "text": null,
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Photo",
              "slug": "photo",
              "status": "active",
              "canonId": "019de52c-fd37-757f-b4a8-ca26d4888875",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "photo",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "c778430f-6c2d-4a8f-a191-5e9959223613",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.22,
            "x": 0.03,
            "y": 0.265
          },
          "kind": "list",
          "text": "Large Established Markets With High Unmet Need",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "6a6bb0de-675d-44ac-9131-8c265977191c",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.22,
            "x": 0.51,
            "y": 0.265
          },
          "kind": "list",
          "text": "THB001: Selective Oral KIT Inhibitor",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "79dba2fc-27c3-41fe-919f-9cd1835ca7a0",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.22,
            "x": 0.75,
            "y": 0.265
          },
          "kind": "list",
          "text": "\"Pipeline-in-a-Product\" Potential",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "99b7ea7f-f5e3-486f-8445-dc1b03e0ad32",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.22,
            "x": 0.27,
            "y": 0.265
          },
          "kind": "list",
          "text": "KIT: A Novel, Clinically Validated Target",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "f1da1b5f-dd74-4f5d-a3de-223806df0e4d",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.15,
            "w": 0.22,
            "x": 0.03,
            "y": 0.715
          },
          "kind": "paragraph",
          "text": "Millions of patients living with severe allergy and other mast cell-mediated diseases; high residual need despite multiple approved products",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "77659ab9-8e30-440f-b33d-3311c99d9322",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.15,
            "w": 0.22,
            "x": 0.27,
            "y": 0.715
          },
          "kind": "paragraph",
          "text": "Clinical validation of KIT as potentially transformative target for mast cell-mediated diseases",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a014a509-1e6e-4c9b-8991-aeeec671f72c",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.15,
            "w": 0.22,
            "x": 0.75,
            "y": 0.715
          },
          "kind": "paragraph",
          "text": "Potential to be an attractive oral treatment option for a range of dermal, airway and GI inflammatory diseases",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "c8001d79-d289-48e7-b7f0-92dc230a12bd",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.15,
            "w": 0.22,
            "x": 0.51,
            "y": 0.715
          },
          "kind": "paragraph",
          "text": "Highly selective oral small molecule with positive clinical responses in Phase 1a clinical trial, PK and PD profile",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "fcc4254b-a4fe-45c9-9bc4-d200ff7cc7a8",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.1,
            "w": 0.9,
            "x": 0.03,
            "y": 0.04
          },
          "kind": "title",
          "text": "Third Harmonic Bio: clinical-stage company with oral wild-type KIT inhibitor to treat mast cell-mediated diseases",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.31+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "fdf73308-5884-4ac6-aeec-64f20314a518",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Executive summary",
            "slug": "executive-summary",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4b63-72d5-9734-da757d91ca61",
            "version": 1,
            "bodyDocId": null,
            "description": "A condensed view of the entire argument on a single slide / block.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "0c2ec08c-1a67-4550-a16c-bcf885994b2a",
          "evidence": "type: executive_summary",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-07-17 00:11:00.170542+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 4,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        },
        {
          "tool": {
            "name": "Problem Statement Canvas",
            "slug": "problem-statement-canvas",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
            "version": 1,
            "bodyDocId": null,
            "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
            "familyLabel": null,
            "categoryName": "Block",
            "categorySlug": "block"
          },
          "agent": "Architect",
          "layer": "slide",
          "agents": [
            "Architect"
          ],
          "matchId": "4db33087-ee40-4a06-a4a2-03f71562bbfb",
          "evidence": "paragraph/paragraph: Millions of patients living with severe allergy and other mast cell-mediated diseases; high residual need despite multiple approved products",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.5,
          "extraction": {
            "at": "2026-07-17 00:11:00.220443+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 4,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [],
      "locked": true
    },
    {
      "page": 5,
      "type": "tension",
      "title": "The slide uses a central hub-and-spoke diagram to show the mast cell as the central point of failure/intervention.",
      "function": "frame_problem",
      "rawType": "problem_statement",
      "block": null,
      "metadata": {
        "slideType": "problem_statement",
        "slideTypeCanon": {
          "name": "Problem statement",
          "slug": "problem_statement",
          "status": "active",
          "canonId": "019de52d-0879-768d-bba8-8da8a5a121d4",
          "version": 1,
          "description": null
        },
        "function": "frame_problem",
        "functionCanon": {
          "name": "Frame problem",
          "slug": "frame_problem",
          "status": "active",
          "canonId": "019de52d-13db-753e-ad70-e9b2d0dab398",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 55,
        "componentCount": 6,
        "textChars": 396,
        "nDataPoints": 0,
        "notes": "The slide uses a central hub-and-spoke diagram to show the mast cell as the central point of failure/intervention.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:18.274+00",
          "seconds": 3.035,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/5",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-5",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.08,
            "w": 0.25,
            "x": 0.38,
            "y": 0.8
          },
          "kind": "callout",
          "text": "Optimal Intervention Point: The Mast Cell Itself",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Callout",
              "slug": "callout",
              "status": "active",
              "canonId": "019de52c-f8d3-761a-8953-7d37080de5e2",
              "version": 1,
              "description": "Highlighted callout box."
            },
            "tool": null,
            "subkind": {
              "name": "Primary callout",
              "slug": "primary",
              "status": "active",
              "canonId": "019de52c-fbd1-70eb-a9ce-8997f8674c1d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "primary",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "194b6c8b-2e0b-4908-9021-61c3097f1f50",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.5,
            "w": 0.3,
            "x": 0.35,
            "y": 0.25
          },
          "kind": "image",
          "text": "Mast cell diagram showing receptors, antigen binding, and degranulation",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Illustration",
              "slug": "illustration",
              "status": "active",
              "canonId": "019de52c-fe76-7772-a5ac-c0b7294d7615",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "illustration",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "794900f9-7170-49ef-8b4e-388a23d5d9e6",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.4,
            "w": 0.25,
            "x": 0.7,
            "y": 0.25
          },
          "kind": "list",
          "text": "Many Mediators: Pre-formed Mediators, Newly Synthesized Mediators, Lymphocyte ligands",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "19b50902-feae-438b-b874-58e4e4db4d03",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.4,
            "w": 0.25,
            "x": 0.08,
            "y": 0.25
          },
          "kind": "list",
          "text": "Many Activators: Receptor-binding agonists, Physical activators, Cell-cell contact",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3178c143-538b-4229-abb9-af87073869cb",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.4,
            "x": 0.03,
            "y": 0.12
          },
          "kind": "title",
          "text": "Current therapeutic approaches are mechanistically limited",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Action title",
              "slug": "action-title",
              "status": "active",
              "canonId": "019de52c-fb31-734c-a0f5-a3935b73135d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "action-title",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e4d991e2-8756-429f-a886-fd7ba0e3b374",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.5,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "Mast Cells are a Fulcrum of Allergy and Inflammation",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "f362a904-ff12-4511-935e-3abce3f32bbe",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "List presentation",
            "slug": "list-presentation",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4ef7-777d-ba68-9074c2b3bcf1",
            "version": 1,
            "bodyDocId": null,
            "description": "Bulleted, numbered, or checklist enumerations.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "15bf74a3-ef6a-4de3-9675-7d8dc34e4940",
          "evidence": "list/bullet: Many Mediators: Pre-formed Mediators, Newly Synthesized Mediators, Lymphocyte ligands",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:11:00.459604+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 5,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        }
      ],
      "frameworks": [
        {
          "matchId": "fc0ee956-f6b7-4497-b4f6-0bad8c2d8117",
          "evidence": "Central mast cell with inputs on left and outputs on right",
          "framework": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-05-02 12:28:18.274+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 5,
          "frameworkName": "hub-spoke"
        }
      ],
      "arcBeats": [
        {
          "to": 6,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 5,
          "name": "Problem",
          "beatId": "d1a3d44c-6014-43c9-929f-a12d0af45eec",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Problem",
            "slug": "sequoia-pitch-problem",
            "status": "active",
            "canonId": "019dd9b8-1ed4-767b-8e05-40e733bd2311",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents the problem statement on pages 5 and 6, highlighting the role of mast cells in allergy and inflammation.",
          "position": 0,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Complication",
            "slug": "complication",
            "status": "active",
            "canonId": "019dd9b8-0275-7709-b2d6-4f77c3fc7579",
            "version": 1,
            "description": "The point in the narrative where the audience should feel discomfort. Required for argumentative arcs."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 6,
      "type": "evidence",
      "title": "The data highlights the mechanism of action of KIT inhibition (inactivation and depletion) supported by Phase 1b interim results.",
      "function": "show_traction",
      "rawType": "traction",
      "block": null,
      "metadata": {
        "slideType": "traction",
        "slideTypeCanon": {
          "name": "Traction",
          "slug": "traction",
          "status": "active",
          "canonId": "019de52d-0edd-72ab-820f-3ebc71a9c542",
          "version": 1,
          "description": null
        },
        "function": "show_traction",
        "functionCanon": {
          "name": "Show traction",
          "slug": "show_traction",
          "status": "active",
          "canonId": "019de52d-16a8-756a-9b38-a7d35420561d",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 52,
        "componentCount": 5,
        "textChars": 383,
        "nDataPoints": 2,
        "notes": "The data highlights the mechanism of action of KIT inhibition (inactivation and depletion) supported by Phase 1b interim results.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:18.448+00",
          "seconds": 2.543,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/6",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-6",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.85,
            "w": 0.48,
            "x": 0.468,
            "y": 0.192
          },
          "kind": "chart",
          "text": "Barzovolimab Phase 1b Chronic Spontaneous Urticaria Interim Data",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.448+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "f17b6eec-9b4b-4b40-bd22-88463bbad16d",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.4,
            "x": 0.03,
            "y": 0.28
          },
          "kind": "paragraph",
          "text": "KIT (CD117) Master regulator of mast cell proliferation, migration, activation and survival. Inhibition of KIT drives both mast cell inactivation and depletion",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.448+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "277680dd-6ce6-4b89-90d5-c3709aa1d1fa",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.02,
            "w": 0.2,
            "x": 0.65,
            "y": 0.84
          },
          "kind": "source-note",
          "text": "Maurer et al., EAACI, July 2022",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.448+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3447efab-3de3-4726-924c-2e1707fd6410",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.5,
            "x": 0.03,
            "y": 0.12
          },
          "kind": "title",
          "text": "Demonstrated clinical efficacy in chronic spontaneous urticaria",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Action title",
              "slug": "action-title",
              "status": "active",
              "canonId": "019de52c-fb31-734c-a0f5-a3935b73135d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "action-title",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.448+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4217f726-cfc6-418d-8fda-015c156ac50b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.7,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "Targeting KIT Has Been Shown To Broadly Inhibit Mast Cell Activity",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.448+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0b943ebd-62b1-4e4a-bc0f-9f430ca64832",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Chart Selection Guide",
            "slug": "chart-selection-guide",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
            "version": 1,
            "bodyDocId": null,
            "description": "Choosing the right chart type for your data and message",
            "familyLabel": null,
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "Designer",
          "layer": "slide",
          "agents": [
            "Designer"
          ],
          "matchId": "a1cc8620-2154-4f28-a0cf-742c2b8af719",
          "evidence": "chart/line: Barzovolimab Phase 1b Chronic Spontaneous Urticaria Interim Data",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:11:00.78451+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 6,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [
        {
          "to": 6,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 5,
          "name": "Problem",
          "beatId": "d1a3d44c-6014-43c9-929f-a12d0af45eec",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Problem",
            "slug": "sequoia-pitch-problem",
            "status": "active",
            "canonId": "019dd9b8-1ed4-767b-8e05-40e733bd2311",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents the problem statement on pages 5 and 6, highlighting the role of mast cells in allergy and inflammation.",
          "position": 0,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Complication",
            "slug": "complication",
            "status": "active",
            "canonId": "019dd9b8-0275-7709-b2d6-4f77c3fc7579",
            "version": 1,
            "description": "The point in the narrative where the audience should feel discomfort. Required for argumentative arcs."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 7,
      "type": "setup",
      "title": "The slide presents a summary of preclinical efficacy and safety data alongside a table demonstrating high selectivity against other kinases.",
      "function": "present_solution",
      "rawType": "product_demo",
      "block": null,
      "metadata": {
        "slideType": "product_demo",
        "slideTypeCanon": {
          "name": "Product demo",
          "slug": "product_demo",
          "status": "active",
          "canonId": "019de52d-0f06-7288-84f2-7568c1020fce",
          "version": 1,
          "description": null
        },
        "function": "present_solution",
        "functionCanon": {
          "name": "Present solution",
          "slug": "present_solution",
          "status": "active",
          "canonId": "019de52d-15b8-71da-bd23-2b767850cbce",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 70,
        "componentCount": 5,
        "textChars": 1060,
        "nDataPoints": 12,
        "notes": "The slide presents a summary of preclinical efficacy and safety data alongside a table demonstrating high selectivity against other kinases.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.031+00",
          "seconds": 3.089,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/7",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-7",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.35,
            "w": 0.17,
            "x": 0.04,
            "y": 0.23
          },
          "kind": "image",
          "text": "Emerging Product Profile",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Infographic",
              "slug": "infographic",
              "status": "active",
              "canonId": "019de52c-fe26-750c-9d7d-9f34e21324e8",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "infographic",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.031+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "ca125bb9-93f8-4aa2-9841-f9e8a7597404",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.65,
            "w": 0.38,
            "x": 0.23,
            "y": 0.23
          },
          "kind": "list",
          "text": "Potent KIT inhibitor; High kinome selectivity; Depleted mast cells in relevant GI, skin and lung tissues of rats and dogs; Demonstrated efficacy in rat models of dermal anaphylaxis and asthma; Favorable pharmacokinetic profile including high oral bioavailability and metabolic stability; No evidence of structural or off-target liabilities; all tox findings on-target and believed to be reversible; Avoids mAb-related risks of infusion events and anaphylaxis",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.031+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b2af16f7-5475-40da-8155-f1dbcf8b7681",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.06,
            "w": 0.76,
            "x": 0.12,
            "y": 0.92
          },
          "kind": "source-note",
          "text": "KIT, CSF1R, PDGFR-beta and PDGFR-alpha most potently inhibited in 231 and 40 kinase panels in biochemical assays and cell based assays, respectively. GI=gastrointestinal; CSF1R=colony stimulating factor 1 receptor; FMS=Feline McDonough sarcoma tyrosine kinase receptor; PDGFR=platelet derived growth factor; FLT3=FMS-related receptor tyrosine kinase 3; mAb=monoclonal antibody",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.031+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "17d6582a-cdfe-40be-94c7-b1ee41a4049b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.45,
            "w": 0.32,
            "x": 0.64,
            "y": 0.28
          },
          "kind": "table",
          "text": "Inhibition of Kinases by THB001 in Ba/F3 Assays: KIT (0.02, -), CSF1R (0.95, 48), PDGFR-beta (2.11, 106), PDGFR-alpha (3.95, 198), FLT3 (>10.7, >535)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.031+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "37fc6251-a144-45cc-96a3-b1edd970cb94",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.035,
            "w": 0.635,
            "x": 0.036,
            "y": 0.065
          },
          "kind": "title",
          "text": "THB001: Highly Selective Oral Wild-Type KIT Inhibitor",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.031+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b40bc63e-48b4-4dbb-8c04-6aa56fe7cfa9",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Table data",
            "slug": "table-data",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
            "version": 1,
            "bodyDocId": null,
            "description": "Tabular layouts of structured data.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "353ff090-edc8-4601-a91c-640a0f6f4d83",
          "evidence": "table/data: Inhibition of Kinases by THB001 in Ba/F3 Assays: KIT (0.02, -), CSF1R (0.95, 48), PDGFR-beta (2.11, 106), PDGFR-alpha (3.95, 198), FLT3 (>10.7, >535)",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:11:00.911833+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 7,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [
        {
          "to": 8,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 7,
          "name": "Solution",
          "beatId": "56e9f7b6-e6ea-4b9d-b393-88a0ff25d5c3",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Solution",
            "slug": "sequoia-pitch-solution",
            "status": "active",
            "canonId": "019dd9b8-1fb1-71d9-a260-07738d7f9c2f",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents the solution on pages 7 and 8, introducing THB001 as a highly selective oral wild-type KIT inhibitor.",
          "position": 1,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Turn",
            "slug": "turn",
            "status": "active",
            "canonId": "019dd9b8-0396-702b-ac2f-9901f8dd8b54",
            "version": 1,
            "description": "The pivot — solution proposed, catalyst introduced, decision made. Common (15/20 arcs) but not universal: Triple-take, AIDA, PAS, Voyage-return and Pixar substitute it with a strong reflection or development beat."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 8,
      "type": "resolution",
      "title": "The slide uses a staircase diagram to represent dose escalation and a crossover diagram for the food effect study.",
      "function": "plan_implementation",
      "rawType": "appendix_methodology",
      "block": null,
      "metadata": {
        "slideType": "appendix_methodology",
        "slideTypeCanon": {
          "name": "Appendix methodology",
          "slug": "appendix_methodology",
          "status": "active",
          "canonId": "019de52d-07d9-726c-8599-167f2d2ffaa7",
          "version": 1,
          "description": null
        },
        "function": "plan_implementation",
        "functionCanon": {
          "name": "Plan implementation",
          "slug": "plan_implementation",
          "status": "active",
          "canonId": "019de52d-14a2-77ea-b210-d6a95eed4823",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 46,
        "componentCount": 4,
        "textChars": 362,
        "nDataPoints": 14,
        "notes": "The slide uses a staircase diagram to represent dose escalation and a crossover diagram for the food effect study.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:18.419+00",
          "seconds": 2.393,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/8",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-8",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.45,
            "w": 0.94,
            "x": 0.03,
            "y": 0.28
          },
          "kind": "diagram",
          "text": "SAD staircase and MAD staircase with central food effect crossover",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Diagram",
              "slug": "diagram",
              "status": "active",
              "canonId": "019de52c-f9f0-734a-81de-15382ff28c65",
              "version": 1,
              "description": "Schematic or relational diagram."
            },
            "tool": null,
            "subkind": {
              "name": "Process flow",
              "slug": "process",
              "status": "active",
              "canonId": "019de52d-039c-718f-ad3a-efe9c4b3c838",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "process",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.419+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "afc497b6-0867-4d3d-9c38-ae22fa901f61",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.7,
            "x": 0.2,
            "y": 0.073
          },
          "kind": "list",
          "text": "Assess safety and tolerability; Characterize pharmacokinetics, including in presence/absence of food to inform further clinical and drug product formulation development; Measure pharmacodynamic effect by serum tryptase",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.419+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b17671b7-83b3-4276-963b-99818ea50c81",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.6,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001: Phase 1 SAD/MAD/Food Effect in Healthy Volunteers",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.419+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "15cc54e8-f6ca-4bef-bd5e-bdef9234a19e",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.2,
            "x": 0.4,
            "y": 0.21
          },
          "kind": "title",
          "text": "Phase 1a Trial Design",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Subtitle",
              "slug": "subtitle",
              "status": "active",
              "canonId": "019de52c-fb09-739d-900c-815b0d9ac526",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "subtitle",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.419+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "39ef3b58-2b65-459f-973f-38125c2cde42",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [
        {
          "matchId": "ed4f3c74-bca5-4350-8584-a79de5571aa8",
          "evidence": "Standard pharmaceutical industry representation of Phase 1 study arms",
          "framework": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-05-02 12:28:18.419+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 8,
          "frameworkName": "clinical-trial-design"
        }
      ],
      "arcBeats": [
        {
          "to": 8,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 7,
          "name": "Solution",
          "beatId": "56e9f7b6-e6ea-4b9d-b393-88a0ff25d5c3",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Solution",
            "slug": "sequoia-pitch-solution",
            "status": "active",
            "canonId": "019dd9b8-1fb1-71d9-a260-07738d7f9c2f",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents the solution on pages 7 and 8, introducing THB001 as a highly selective oral wild-type KIT inhibitor.",
          "position": 1,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Turn",
            "slug": "turn",
            "status": "active",
            "canonId": "019dd9b8-0396-702b-ac2f-9901f8dd8b54",
            "version": 1,
            "description": "The pivot — solution proposed, catalyst introduced, decision made. Common (15/20 arcs) but not universal: Triple-take, AIDA, PAS, Voyage-return and Pixar substitute it with a strong reflection or development beat."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 9,
      "type": "analysis",
      "title": "The chart displays multiple dose cohorts (200mg QD, 200mg BID, 400mg BID, 500mg QD FED) with error bars representing standard deviation.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 47,
        "componentCount": 5,
        "textChars": 243,
        "nDataPoints": 12,
        "notes": "The chart displays multiple dose cohorts (200mg QD, 200mg BID, 400mg BID, 500mg QD FED) with error bars representing standard deviation.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.356+00",
          "seconds": 3.184,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/9",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-9",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.7,
            "w": 0.6,
            "x": 0.03,
            "y": 0.2
          },
          "kind": "chart",
          "text": "THB001 Multiple Dose PK (14 days)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.356+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "00325c58-25a4-43de-9a1c-fde6983642bf",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.25,
            "x": 0.7,
            "y": 0.3
          },
          "kind": "list",
          "text": "Unbound THB001 Trough Values vs KIT Cellular IC50: 200mg QD: ~1.5-2-fold, 200mg BID: ~10-fold, 500mg QD FED: ~10-fold, 400mg BID: ~20-fold",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.356+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "5f04d2e3-2bcc-493f-84f5-c3e98225af19",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.2,
            "x": 0.7,
            "y": 0.6
          },
          "kind": "paragraph",
          "text": "Mean t1/2 ~24 hours",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.356+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "7d458007-c85c-4505-9217-3c4dc82b2306",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.2,
            "x": 0.12,
            "y": 0.94
          },
          "kind": "source-note",
          "text": "1. Protein binding adjusted KIT IC50",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.356+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "986ee084-bd82-4601-9e2e-fa7da9305528",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.04,
            "w": 0.25,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001 PK Summary",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.356+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "bb090d29-ac6f-408c-a418-78c382dc3c55",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Chartjunk Elimination",
            "slug": "chartjunk-elimination",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-b49e-7453-ab01-b60f338eeda1",
            "version": 1,
            "bodyDocId": null,
            "description": "Remove decorative elements that don't convey data: 3D effects, shadows, unnecessary gridlines",
            "familyLabel": null,
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "Designer",
          "layer": "slide",
          "agents": [
            "Designer"
          ],
          "matchId": "be858f9e-cde1-44b4-b0cf-a235e2269681",
          "evidence": "The line chart for THB001 Multiple Dose PK (14 days) appears to effectively communicate data without unnecessary elements.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:58.99065+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 9,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 10,
      "type": "analysis",
      "title": "The table displays counts and percentages of subjects experiencing specific adverse events. 'MAD' stands for Multiple Ascending Dose.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 44,
        "componentCount": 3,
        "textChars": 472,
        "nDataPoints": 64,
        "notes": "The table displays counts and percentages of subjects experiencing specific adverse events. 'MAD' stands for Multiple Ascending Dose.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:18.907+00",
          "seconds": 2.688,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/10",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-10",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.55,
            "w": 0.35,
            "x": 0.03,
            "y": 0.25
          },
          "kind": "list",
          "text": "No dose escalation or study stopping criteria met. No clinically significant trends in chemistries, vital signs or ECGs observed. No SAEs reported. 3 moderate AEs reported, 1 that led to discontinuation. 1 mild AE reported that led to discontinuation.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.907+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "88dc90b1-51bf-4d83-aa65-65247fe278c0",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.65,
            "w": 0.61,
            "x": 0.36,
            "y": 0.208
          },
          "kind": "table",
          "text": "MAD Treatment Emergent Adverse Events table showing Preferred Terms (Hair Color Changes, Headache, Nausea, etc.) across THB001 dosage groups (200mg QD, 200mg BID, 500mg QD FED, 400mg BID) and PBO.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.907+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "7f1f8bf5-77b5-4848-8355-ebd06f5b2644",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.35,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001 MAD Safety Summary",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:18.907+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "2bfe58df-620d-4f4b-96d5-e56a698aace6",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Table data",
            "slug": "table-data",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
            "version": 1,
            "bodyDocId": null,
            "description": "Tabular layouts of structured data.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "ab0ce22a-eb97-49d5-a031-f38b2ed19eef",
          "evidence": "The MAD Treatment Emergent Adverse Events table clearly presents data in a structured format.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-07-17 00:10:59.071333+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 10,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 11,
      "type": "analysis",
      "title": "The chart tracks neutrophil levels across multiple cohorts (placebo, 200mg QD, 200mg Q12H, 400mg Q12H, 500mg QD FED) from Day 1 to Day 70/EOS, with a vertical l",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 43,
        "componentCount": 4,
        "textChars": 290,
        "nDataPoints": 55,
        "notes": "The chart tracks neutrophil levels across multiple cohorts (placebo, 200mg QD, 200mg Q12H, 400mg Q12H, 500mg QD FED) from Day 1 to Day 70/EOS, with a vertical line marking the end of treatment at Day 14.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.323+00",
          "seconds": 3.019,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/11",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-11",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.7,
            "w": 0.6,
            "x": 0.1,
            "y": 0.2
          },
          "kind": "chart",
          "text": "Neutrophils (10^9/L) over Study Day",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.323+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b9abbe13-c7fe-43ea-91fc-0fb45ac89c76",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.25,
            "x": 0.7,
            "y": 0.45
          },
          "kind": "list",
          "text": "Placebo multiple dose; 200mg THB001 multiple dose QD; 200mg THB001 multiple dose Q12H; 400mg THB001 multiple dose Q12H; 500mg THB001 multiple dose QD FED",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.323+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "7f4a0638-5f40-4755-afba-a8a5f11c085a",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.25,
            "x": 0.7,
            "y": 0.7
          },
          "kind": "subtitle",
          "text": "ULN=upper limit of normal; LLN=lower limit of normal",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Subtitle",
              "slug": "subtitle",
              "status": "active",
              "canonId": "82d821ee-2793-42e7-8f16-c6131385a3ce",
              "version": 1,
              "description": "Header-zone supporting text near the title (= ex body.description with bbox)."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.323+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e18941bd-cc87-42c7-bd86-5159a9e5b97b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.5,
            "x": 0.03,
            "y": 0.07
          },
          "kind": "title",
          "text": "THB001 Hematology – Mean Neutrophil Count (+/- SD)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.323+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "db09cf99-2fa9-4db7-8f3c-3acbd4b17766",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Chart Selection Guide",
            "slug": "chart-selection-guide",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
            "version": 1,
            "bodyDocId": null,
            "description": "Choosing the right chart type for your data and message",
            "familyLabel": null,
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "Designer",
          "layer": "slide",
          "agents": [
            "Designer"
          ],
          "matchId": "8acdb670-eda8-4d94-9c03-b80beb3b7925",
          "evidence": "The line chart for Neutrophils (10^9/L) over Study Day effectively displays data for comparison across different treatment groups.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:59.158774+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 11,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 12,
      "type": "analysis",
      "title": "The slide includes a disclaimer that cross-study comparisons are unreliable due to differences in study design.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 56,
        "componentCount": 4,
        "textChars": 590,
        "nDataPoints": 50,
        "notes": "The slide includes a disclaimer that cross-study comparisons are unreliable due to differences in study design.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.241+00",
          "seconds": 2.752,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/12",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-12",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.08,
            "w": 0.9,
            "x": 0.05,
            "y": 0.9
          },
          "kind": "disclaimer",
          "text": "1.Alvarado, D. et al. Allergy (2022) doi:10.1111/all.15262. Each of the candidates were tested in a different clinical trial and comparing results from different studies may be unreliable due to differences between the studies with respect to study design, objectives, and other parameters, and there can be no assurances regarding the performance of THB001 relative to Barzovolimab or any other drug in a head-to-head trial. Mean(SD).",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Disclaimer",
              "slug": "disclaimer",
              "status": "active",
              "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc",
              "version": 1,
              "description": "Legal/cautionary text that occupies most of the body of its slide."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.241+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "de03a2c9-1fc9-4291-9fce-3b87846d52b8",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.6,
            "w": 0.76,
            "x": 0.12,
            "y": 0.25
          },
          "kind": "table",
          "text": "THB001 and Barzovolimab hematology data tables",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.241+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "5a08116c-e053-4940-9539-df2af490878b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.9,
            "x": 0.05,
            "y": 0.05
          },
          "kind": "title",
          "text": "Hematology Parameter Comparison –THB001 and Barzovolimab in NHVs",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.241+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "db59e3c7-39aa-4993-be65-fede3e75ca6a",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.4,
            "x": 0.3,
            "y": 0.15
          },
          "kind": "title",
          "text": "Change from Baseline to Post-Baseline Minimum",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Subtitle",
              "slug": "subtitle",
              "status": "active",
              "canonId": "019de52c-fb09-739d-900c-815b0d9ac526",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "subtitle",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.241+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a54de048-2ae6-49e5-a975-c5f25c217b0d",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Table data",
            "slug": "table-data",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd9e1-4fab-7168-a82f-b847350a006d",
            "version": 1,
            "bodyDocId": null,
            "description": "Tabular layouts of structured data.",
            "familyLabel": null,
            "categoryName": null,
            "categorySlug": null
          },
          "agent": null,
          "layer": "slide",
          "agents": null,
          "matchId": "c1b7c037-94bb-4fe8-97ef-c63f5ff00669",
          "evidence": "The THB001 and Barzovolimab hematology data tables present comparative data in a clear and organized manner.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-07-17 00:10:59.241811+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 12,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": "common",
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 13,
      "type": "analysis",
      "title": "Includes two line charts: one normalized to baseline and one showing absolute values.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 35,
        "componentCount": 4,
        "textChars": 176,
        "nDataPoints": 20,
        "notes": "Includes two line charts: one normalized to baseline and one showing absolute values.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:21.925+00",
          "seconds": 5.308,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/13",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-13",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.7,
            "w": 0.45,
            "x": 0.03,
            "y": 0.2
          },
          "kind": "chart",
          "text": "Serum Tryptase Normalized to Baseline Over Time",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.925+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "ef93e81f-a80a-4a57-b950-005b03ceae33",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.7,
            "w": 0.45,
            "x": 0.52,
            "y": 0.2
          },
          "kind": "chart",
          "text": "Mean Absolute Serum Tryptase Over Time",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.925+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "f8c6093b-c382-4910-9bd6-b719d3c37abd",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.25,
            "x": 0.52,
            "y": 0.85
          },
          "kind": "source-note",
          "text": "LLOQ=lower limit of quantitation; Mean ± SD; PBO = placebo",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.925+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0a38bcf8-9984-483f-86f0-714b251721b1",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.04,
            "w": 0.4,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001 PD Summary: Serum Tryptase",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.925+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "bf9bed0c-63c1-497f-bd6f-1213be9ff38a",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Chartjunk Elimination",
            "slug": "chartjunk-elimination",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-b49e-7453-ab01-b60f338eeda1",
            "version": 1,
            "bodyDocId": null,
            "description": "Remove decorative elements that don't convey data: 3D effects, shadows, unnecessary gridlines",
            "familyLabel": null,
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "Designer",
          "layer": "slide",
          "agents": [
            "Designer"
          ],
          "matchId": "46feb3db-b565-4970-a2d0-5160647e31af",
          "evidence": "The line charts for Serum Tryptase Normalized to Baseline Over Time and Mean Absolute Serum Tryptase Over Time effectively communicate data without unnecessary elements.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:59.328505+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 13,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 14,
      "type": "resolution",
      "title": "The schematic illustrates a dose escalation study with three cohorts of 10 patients each, separated by safety review committee (SRC) checkpoints.",
      "function": "plan_implementation",
      "rawType": "appendix_methodology",
      "block": null,
      "metadata": {
        "slideType": "appendix_methodology",
        "slideTypeCanon": {
          "name": "Appendix methodology",
          "slug": "appendix_methodology",
          "status": "active",
          "canonId": "019de52d-07d9-726c-8599-167f2d2ffaa7",
          "version": 1,
          "description": null
        },
        "function": "plan_implementation",
        "functionCanon": {
          "name": "Plan implementation",
          "slug": "plan_implementation",
          "status": "active",
          "canonId": "019de52d-14a2-77ea-b210-d6a95eed4823",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 61,
        "componentCount": 5,
        "textChars": 593,
        "nDataPoints": 4,
        "notes": "The schematic illustrates a dose escalation study with three cohorts of 10 patients each, separated by safety review committee (SRC) checkpoints.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.796+00",
          "seconds": 3.108,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/14",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-14",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.65,
            "w": 0.48,
            "x": 0.48,
            "y": 0.2
          },
          "kind": "diagram",
          "text": "Study Schematic showing screening, three treatment arms (200mg, 300mg, 400mg BID), SRC checkpoints, and follow-up periods.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Diagram",
              "slug": "diagram",
              "status": "active",
              "canonId": "019de52c-f9f0-734a-81de-15382ff28c65",
              "version": 1,
              "description": "Schematic or relational diagram."
            },
            "tool": null,
            "subkind": {
              "name": "Process flow",
              "slug": "process",
              "status": "active",
              "canonId": "019de52d-039c-718f-ad3a-efe9c4b3c838",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "process",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "d0e15cd9-bd85-416c-93ec-1d2b8c25f7d0",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.4,
            "x": 0.03,
            "y": 0.22
          },
          "kind": "list",
          "text": "Design: Open label, dose escalation design; 3 doses (1:1:1) of THB001 (total N=30) for 12 weeks on treatment; Generally healthy male and female patients aged 18-75 with Dx'd Cold Induced Urticaria",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "5642a9e5-4744-4493-90df-5f7a49cec663",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.45,
            "x": 0.03,
            "y": 0.55
          },
          "kind": "list",
          "text": "Objectives: Safety and Tolerability; Mean reduction in critical temperature threshold (CTT) using the TempTest system; PK, serum tryptase; Clinical outcome measures (e.g., ColdUAS, ColdU-QoL)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "79d1a641-3f80-4584-8aa5-2af0ac110ccb",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.15,
            "x": 0.48,
            "y": 0.84
          },
          "kind": "source-note",
          "text": "SRC=safety review committee",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "c8653d9e-c3a9-4e26-9669-6f246c211ad1",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.6,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "Phase 1b Chronic Inducible Urticaria (CIndU) Study Design",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "7723ad48-e8c9-4d50-a432-c26c3e854037",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [
        {
          "matchId": "18db4989-fb48-4b98-b91e-3d26fb65b58b",
          "evidence": "Schematic representation of patient cohorts, dosing, and follow-up",
          "framework": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-05-02 12:28:19.796+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 14,
          "frameworkName": "clinical-trial-design"
        }
      ],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 15,
      "type": "evidence",
      "title": "The chart shows a pharmacokinetic (PK) profile comparing two formulations of THB001.",
      "function": "analyze_data",
      "rawType": "traction",
      "block": null,
      "metadata": {
        "slideType": "traction",
        "slideTypeCanon": {
          "name": "Traction",
          "slug": "traction",
          "status": "active",
          "canonId": "019de52d-0edd-72ab-820f-3ebc71a9c542",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "balanced",
        "densityScore": 42,
        "componentCount": 4,
        "textChars": 352,
        "nDataPoints": 2,
        "notes": "The chart shows a pharmacokinetic (PK) profile comparing two formulations of THB001.",
        "elementsJson": null,
        "confidence": 0.95,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:19.256+00",
          "seconds": 2.455,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/15",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-15",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.65,
            "w": 0.48,
            "x": 0.04,
            "y": 0.235
          },
          "kind": "chart",
          "text": "THB001 Interim Human BioA Data (200mg crossover)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.256+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3881e80d-ce59-4514-b2fe-77256a602e6d",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.4,
            "w": 0.4,
            "x": 0.57,
            "y": 0.33
          },
          "kind": "list",
          "text": "~3x increase in exposure\nFavorable PK profile\nSupports potential for QD dosing\nManufacturing underway to introduce into upcoming clinical studies – no additional tox/clinical requirements to support transition to new formulation",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.256+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0b9cdb14-40d4-444f-bfa1-0bbb8bfea0b2",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.02,
            "w": 0.05,
            "x": 0.46,
            "y": 0.85
          },
          "kind": "source-note",
          "text": "Mean ± SD",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.256+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "54b239c5-9127-4314-bf1a-f6ebcf3c87df",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.8,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001 CMC Development: Second-Generation Formulation to Enter 2023",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:19.256+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "6fc7969a-ce1b-4e85-8d6d-f9e8a43cabfb",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Chart Selection Guide",
            "slug": "chart-selection-guide",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-b1a0-700b-ba17-0e16c4d5bcae",
            "version": 1,
            "bodyDocId": null,
            "description": "Choosing the right chart type for your data and message",
            "familyLabel": null,
            "categoryName": "Slide",
            "categorySlug": "slide"
          },
          "agent": "Designer",
          "layer": "slide",
          "agents": [
            "Designer"
          ],
          "matchId": "c499b99d-efdb-4242-acac-d1711df4afd6",
          "evidence": "The line chart for THB001 Interim Human BioA Data (200mg crossover) effectively displays data to support the ~3x increase in exposure claim.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:59.457291+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 15,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 16,
      "type": "appendix",
      "title": "The slide uses clinical data to justify a new indication for a drug candidate by highlighting the role of mast cells in asthma pathophysiology.",
      "function": "establish_context",
      "rawType": "other",
      "block": null,
      "metadata": {
        "slideType": "other",
        "slideTypeCanon": {
          "name": "Other (fallback)",
          "slug": "other",
          "status": "active",
          "canonId": "019de52d-0af5-71ed-83de-d51ae245fc43",
          "version": 1,
          "description": null
        },
        "function": "establish_context",
        "functionCanon": {
          "name": "Establish context",
          "slug": "establish_context",
          "status": "active",
          "canonId": "019de52d-1314-74e6-9074-d213dc0bdcdf",
          "version": 1,
          "description": null
        },
        "density": "overcrowded",
        "densityScore": 80,
        "componentCount": 8,
        "textChars": 654,
        "nDataPoints": 2,
        "notes": "The slide uses clinical data to justify a new indication for a drug candidate by highlighting the role of mast cells in asthma pathophysiology.",
        "elementsJson": null,
        "confidence": 0.95,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:22.777+00",
          "seconds": 5.972,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/16",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-16",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.15,
            "w": 0.35,
            "x": 0.58,
            "y": 0.25
          },
          "kind": "callout",
          "text": "Gleevec (Imatinib) In Severe Refractory Asthma",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Callout",
              "slug": "callout",
              "status": "active",
              "canonId": "019de52c-f8d3-761a-8953-7d37080de5e2",
              "version": 1,
              "description": "Highlighted callout box."
            },
            "tool": null,
            "subkind": {
              "name": "Primary callout",
              "slug": "primary",
              "status": "active",
              "canonId": "019de52c-fbd1-70eb-a9ce-8997f8674c1d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "primary",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "754d5ab0-d021-453b-8613-535b6499f5c4",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.3,
            "w": 0.2,
            "x": 0.05,
            "y": 0.55
          },
          "kind": "chart",
          "text": "Lung Tryptase",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Vertical bar chart",
              "slug": "bar-vertical",
              "status": "active",
              "canonId": "019de52c-fe9d-70f2-b3b7-a9ae294f5917",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bar-vertical",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "15002cd8-00fd-4d2e-bf8a-aaf00e410f2d",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.3,
            "w": 0.2,
            "x": 0.28,
            "y": 0.55
          },
          "kind": "chart",
          "text": "Plasma Tryptase",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Box plot",
              "slug": "box",
              "status": "active",
              "canonId": "019de52d-020e-73d9-b4cf-5793a03e9b74",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "box",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "2706fa8f-79a2-45c5-969b-1114faa4aa4d",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.3,
            "w": 0.4,
            "x": 0.58,
            "y": 0.42
          },
          "kind": "list",
          "text": "Moderately potent KIT inhibitor\n43% reduction in serum tryptase --> significant improvements in FEV1 and airway hyperreactivity\nNon-endotype restricted study population\nProvides human PoC, even with suboptimal KIT inhibition",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0d99a19c-6167-47d2-ab03-6ca1bf4d1131",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.45,
            "x": 0.05,
            "y": 0.18
          },
          "kind": "list",
          "text": "Asthma severity correlates with lung mast cell number, localization and phenotype\nMast cell changes are independent of biomarker status (i.e., blood eosinophils)\nMast cells required for IgE-dependent and -independent TSLP production in rodents",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "186b6261-4e66-4b86-ba09-cff5afe13af7",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.4,
            "x": 0.05,
            "y": 0.12
          },
          "kind": "paragraph",
          "text": "Mast cells are central to asthma pathophysiology",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "08f65e21-b28d-4a00-a489-5931b23b9eb1",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.02,
            "w": 0.1,
            "x": 0.85,
            "y": 0.9
          },
          "kind": "source-note",
          "text": "Cahill, et al., NEJM, May 2017",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4603b2fa-1007-4203-a890-c35a330ce545",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.4,
            "x": 0.05,
            "y": 0.05
          },
          "kind": "title",
          "text": "Indication Expansion: Severe Asthma",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.777+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "8aa2b5db-d2a6-4c37-bc18-880055f2f9eb",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 17,
      "type": "resolution",
      "title": "The slide outlines a randomized, placebo-controlled trial structure with specific allergen challenge points.",
      "function": "plan_implementation",
      "rawType": "appendix_methodology",
      "block": null,
      "metadata": {
        "slideType": "appendix_methodology",
        "slideTypeCanon": {
          "name": "Appendix methodology",
          "slug": "appendix_methodology",
          "status": "active",
          "canonId": "019de52d-07d9-726c-8599-167f2d2ffaa7",
          "version": 1,
          "description": null
        },
        "function": "plan_implementation",
        "functionCanon": {
          "name": "Plan implementation",
          "slug": "plan_implementation",
          "status": "active",
          "canonId": "019de52d-14a2-77ea-b210-d6a95eed4823",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 52,
        "componentCount": 5,
        "textChars": 512,
        "nDataPoints": 0,
        "notes": "The slide outlines a randomized, placebo-controlled trial structure with specific allergen challenge points.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.617+00",
          "seconds": 3.673,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/17",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-17",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.4,
            "w": 0.65,
            "x": 0.03,
            "y": 0.25
          },
          "kind": "diagram",
          "text": "Trial timeline showing weeks, days, allergen challenges, SPT, and AHR measurements.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Diagram",
              "slug": "diagram",
              "status": "active",
              "canonId": "019de52c-f9f0-734a-81de-15382ff28c65",
              "version": 1,
              "description": "Schematic or relational diagram."
            },
            "tool": null,
            "subkind": {
              "name": "Timeline",
              "slug": "timeline",
              "status": "active",
              "canonId": "019de52d-03c5-73fc-84aa-4180cbf0f5cf",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "timeline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.617+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a0310e72-10f3-4230-acb5-6ffd015a8b57",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.6,
            "w": 0.25,
            "x": 0.7,
            "y": 0.25
          },
          "kind": "list",
          "text": "Established clinical POC model for asthma. Elevated mast cell gene signature. Dose ranging design. Planned study initiation in 1H:23.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.617+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "5164f6bf-9990-4e30-8f9e-8fab6383e353",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.65,
            "x": 0.03,
            "y": 0.7
          },
          "kind": "list",
          "text": "Study Design: Parallel, Blinded, PBO controlled, 2-3 THB001 doses + PBO (1:1:1): N=~10-15/arm. Patient Population: mild, stable allergic asthmatic subjects. Primary Endpoint: change from baseline in FEV during LAR.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.617+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "f863e5be-5901-4360-9147-b150118f69c0",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.12,
            "x": 0.83,
            "y": 0.82
          },
          "kind": "source-note",
          "text": "1Murphy et al. ACS 2022",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.617+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a0257cbe-612e-4c3d-a25d-b5f8928841ea",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.6,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "Phase 1b Inducible Allergic Asthma POC Trial Concept Design",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.617+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a2d863d0-cf59-4200-b7dc-395703ab4f10",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 18,
      "type": "resolution",
      "title": "The slide uses a timeline diagram to show clinical phases and key events (trial initiation, regulatory submission, data readout) from 2H'22 to 2H'24.",
      "function": "plan_implementation",
      "rawType": "roadmap",
      "block": null,
      "metadata": {
        "slideType": "roadmap",
        "slideTypeCanon": {
          "name": "Roadmap",
          "slug": "roadmap",
          "status": "active",
          "canonId": "019de52d-0a55-72bc-9b7b-a47ef109839c",
          "version": 1,
          "description": null
        },
        "function": "plan_implementation",
        "functionCanon": {
          "name": "Plan implementation",
          "slug": "plan_implementation",
          "status": "active",
          "canonId": "019de52d-14a2-77ea-b210-d6a95eed4823",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 63,
        "componentCount": 6,
        "textChars": 471,
        "nDataPoints": 1,
        "notes": "The slide uses a timeline diagram to show clinical phases and key events (trial initiation, regulatory submission, data readout) from 2H'22 to 2H'24.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.586+00",
          "seconds": 3.403,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/18",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-18",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.45,
            "w": 0.96,
            "x": 0.02,
            "y": 0.228
          },
          "kind": "diagram",
          "text": "Anticipated Milestones timeline for Chronic inducible urticaria, Asthma, and Chronic spontaneous urticaria",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Diagram",
              "slug": "diagram",
              "status": "active",
              "canonId": "019de52c-f9f0-734a-81de-15382ff28c65",
              "version": 1,
              "description": "Schematic or relational diagram."
            },
            "tool": null,
            "subkind": {
              "name": "Timeline",
              "slug": "timeline",
              "status": "active",
              "canonId": "019de52d-03c5-73fc-84aa-4180cbf0f5cf",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "timeline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "ee5926e9-8cca-4609-9653-01751f7d64ad",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.1,
            "x": 0.3,
            "y": 0.78
          },
          "kind": "metric",
          "text": "$113M",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Metric",
              "slug": "metric",
              "status": "active",
              "canonId": "019de52c-f923-73bf-8081-d0b1a8c5264d",
              "version": 1,
              "description": "Big-number or KPI value."
            },
            "tool": null,
            "subkind": {
              "name": "Big number",
              "slug": "big-number",
              "status": "active",
              "canonId": "019de52c-fc70-70c8-b965-0584548a9204",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "big-number",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "73cc42d2-2290-43e1-b832-6e6d55fbcee3",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.1,
            "w": 0.65,
            "x": 0.3,
            "y": 0.78
          },
          "kind": "paragraph",
          "text": "Cash and cash equivalents: $113M as of June 30, 2022 (unaudited). Proceeds from this offering together with cash and cash equivalents expected to fund operations through 2025",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "45bc65e2-4467-41a1-8ec5-2422bbf7ab75",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.6,
            "x": 0.02,
            "y": 0.94
          },
          "kind": "source-note",
          "text": "1. Regulatory submission = Clinical Trial Application (CTA) in Europe and Investigational New Drug application in U.S.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "3095bbff-3fe3-4f95-9940-302d11931704",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.1,
            "w": 0.2,
            "x": 0.02,
            "y": 0.78
          },
          "kind": "title",
          "text": "Financials & Cash Runway",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "8bea17d9-a7b2-44b6-9fea-2419db67e342",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.45,
            "x": 0.02,
            "y": 0.07
          },
          "kind": "title",
          "text": "THB001: Multiple Upcoming Clinical Catalysts",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "c782faf6-916b-482c-a162-e6a922a9a128",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [
        {
          "matchId": "e449a310-7896-43dc-b21a-9c71161318a0",
          "evidence": "Timeline visualization of clinical milestones over time",
          "framework": null,
          "confidence": 0.9,
          "extraction": {
            "at": "2026-05-02 12:28:20.586+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 18,
          "frameworkName": "gantt-chart"
        }
      ],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        },
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 19,
      "type": "appendix",
      "function": "appendix",
      "rawType": "appendix",
      "block": null,
      "metadata": {
        "slideType": "appendix",
        "slideTypeCanon": {
          "name": "Appendix",
          "slug": "appendix",
          "status": "active",
          "canonId": "019de52d-0762-71f8-b564-89ab863301cc",
          "version": 1,
          "description": null
        },
        "function": "appendix",
        "functionCanon": {
          "name": "Appendix",
          "slug": "appendix",
          "status": "active",
          "canonId": "019de52d-138d-750b-83c3-49b4bc7a7a38",
          "version": 1,
          "description": null
        },
        "density": "sparse",
        "densityScore": 23,
        "componentCount": 4,
        "textChars": 131,
        "nDataPoints": 0,
        "notes": null,
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.094+00",
          "seconds": 2.838,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/19",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-19",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.02,
            "w": 0.15,
            "x": 0.04,
            "y": 0.95
          },
          "kind": "disclaimer",
          "text": "©2022 THIRD HARMONIC BIO",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Disclaimer",
              "slug": "disclaimer",
              "status": "active",
              "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc",
              "version": 1,
              "description": "Legal/cautionary text that occupies most of the body of its slide."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.094+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "05a49cf2-82e3-4a38-9889-c1532fd797ea",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.18,
            "w": 0.25,
            "x": 0.65,
            "y": 0.415
          },
          "kind": "image",
          "text": "Third Harmonic Bio",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Logo",
              "slug": "logo",
              "status": "active",
              "canonId": "019de52c-fdaf-743d-94c4-d7c6a0e55302",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "logo",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.094+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e012c058-e842-431f-afb7-c6968ab717b7",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.2,
            "x": 0.04,
            "y": 0.89
          },
          "kind": "paragraph",
          "text": "APPENDIX | SEPTEMBER 2022",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "5f2affc0-941d-4d07-959d-4bfc1930cea4",
              "version": 1,
              "description": "Single prose block in the body of a slide."
            },
            "tool": null,
            "subkind": {
              "name": "Paragraph",
              "slug": "paragraph",
              "status": "active",
              "canonId": "019de52c-fb80-75af-aa5c-a7a4bfac2433",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "paragraph",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.094+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "db54f2f4-35e5-4282-8853-442eaba98837",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.45,
            "x": 0.04,
            "y": 0.38
          },
          "kind": "title",
          "text": "Advancing the Next Wave of Medicine for Allergy and Inflammation",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.094+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "323ef9fc-604a-4ee2-9f22-39355a1246f5",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        },
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 20,
      "type": "tension",
      "title": "Includes a patient quote and clinical imagery to emphasize the severity of the condition.",
      "function": "frame_problem",
      "rawType": "problem_statement",
      "block": null,
      "metadata": {
        "slideType": "problem_statement",
        "slideTypeCanon": {
          "name": "Problem statement",
          "slug": "problem_statement",
          "status": "active",
          "canonId": "019de52d-0879-768d-bba8-8da8a5a121d4",
          "version": 1,
          "description": null
        },
        "function": "frame_problem",
        "functionCanon": {
          "name": "Frame problem",
          "slug": "frame_problem",
          "status": "active",
          "canonId": "019de52d-13db-753e-ad70-e9b2d0dab398",
          "version": 1,
          "description": null
        },
        "density": "overcrowded",
        "densityScore": 75,
        "componentCount": 6,
        "textChars": 897,
        "nDataPoints": 5,
        "notes": "Includes a patient quote and clinical imagery to emphasize the severity of the condition.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:22.914+00",
          "seconds": 5.462,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/20",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-20",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.38,
            "w": 0.485,
            "x": 0.055,
            "y": 0.458
          },
          "kind": "image",
          "text": "Clinical images of urticaria",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Photo",
              "slug": "photo",
              "status": "active",
              "canonId": "019de52c-fd37-757f-b4a8-ca26d4888875",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "photo",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4f1c2737-cea1-4c38-9449-c5f6923113b3",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.6,
            "w": 0.45,
            "x": 0.52,
            "y": 0.235
          },
          "kind": "list",
          "text": "Prevalence: More than 1.5 million patients or 0.5-1% point prevalence; ~70-80% female, mean age ~46 years\nSymptoms: severely itchy, painful wheals and angioedema which confer significant mental health and quality of life burdens\nEtiology: both inducible (caused by specific stimuli/triggers) and spontaneous (no identified stimuli, potentially auto-immune) forms\nCurrent treatment options are limited: oral anti-histamines only effective in about half of patients; single biologic therapy approved for second-line use\nNew treatment options with the potential to achieve robust disease control are imperative to driving awareness, diagnosis and treatment",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "626fe2ca-3ef9-4e1e-8186-24a985e051f6",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.12,
            "w": 0.41,
            "x": 0.045,
            "y": 0.275
          },
          "kind": "quote",
          "text": "Out there, it’s a horrible world for urticaria patients",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Quote",
              "slug": "quote",
              "status": "active",
              "canonId": "019de52c-f8fb-751e-8bc6-d58e2d59562a",
              "version": 1,
              "description": "Pull quote or testimonial."
            },
            "tool": null,
            "subkind": {
              "name": "Pull quote",
              "slug": "pull-quote",
              "status": "active",
              "canonId": "019de52c-fbf9-76fe-97e1-a0b7540445c9",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "pull-quote",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a15d82bc-aa42-4e15-a295-617377e719fe",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.02,
            "w": 0.33,
            "x": 0.108,
            "y": 0.96
          },
          "kind": "source-note",
          "text": "1Marcus Mauer MD, LifeSci Immunology and Inflammation Day, May 10, 2022",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b1a742eb-77df-4920-9268-9d7aa50d02a1",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.025,
            "w": 0.492,
            "x": 0.036,
            "y": 0.125
          },
          "kind": "title",
          "text": "A severe, yet undertreated dermal inflammatory condition",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Action title",
              "slug": "action-title",
              "status": "active",
              "canonId": "019de52c-fb31-734c-a0f5-a3935b73135d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "action-title",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "066f6cce-cd46-4883-8960-9073b35718fe",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.038,
            "w": 0.448,
            "x": 0.036,
            "y": 0.068
          },
          "kind": "title",
          "text": "Chronic Urticaria Disease Overview",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:22.914+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e35e189f-13c2-4e51-9332-efe543935d6a",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Problem Statement Canvas",
            "slug": "problem-statement-canvas",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
            "version": 1,
            "bodyDocId": null,
            "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
            "familyLabel": null,
            "categoryName": "Block",
            "categorySlug": "block"
          },
          "agent": "Architect",
          "layer": "slide",
          "agents": [
            "Architect"
          ],
          "matchId": "0eb71c1a-ae3e-4aa6-8482-8538df98172f",
          "evidence": "The Chronic Urticaria Disease Overview effectively frames the problem with bulleted points and supporting data.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:59.709791+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 20,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [
        {
          "to": 21,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 20,
          "name": "Market Size",
          "beatId": "3071eeb1-d844-41d8-a60d-a94623bcd39f",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Market Size",
            "slug": "sequoia-pitch-market-size",
            "status": "active",
            "canonId": "019dd9b8-20e6-729c-bc28-05442906d032",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents an overview of the market size on pages 20 and 21, discussing chronic urticaria and severe asthma.",
          "position": 2,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Evidence",
            "slug": "evidence",
            "status": "active",
            "canonId": "019dd9b8-03f9-772a-b84a-4f07b415b77a",
            "version": 1,
            "description": "A dedicated proof beat exists in only ~4 arcs (Gambit, Sequoia, AIDA, Monroes). Other arcs embed evidence inline within development."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        },
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 21,
      "type": "tension",
      "title": "Includes medical imagery of lungs and mast cells.",
      "function": "frame_problem",
      "rawType": "problem_statement",
      "block": null,
      "metadata": {
        "slideType": "problem_statement",
        "slideTypeCanon": {
          "name": "Problem statement",
          "slug": "problem_statement",
          "status": "active",
          "canonId": "019de52d-0879-768d-bba8-8da8a5a121d4",
          "version": 1,
          "description": null
        },
        "function": "frame_problem",
        "functionCanon": {
          "name": "Frame problem",
          "slug": "frame_problem",
          "status": "active",
          "canonId": "019de52d-13db-753e-ad70-e9b2d0dab398",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 66,
        "componentCount": 5,
        "textChars": 816,
        "nDataPoints": 4,
        "notes": "Includes medical imagery of lungs and mast cells.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.577+00",
          "seconds": 3.02,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/21",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-21",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.2,
            "w": 0.256,
            "x": 0.064,
            "y": 0.26
          },
          "kind": "image",
          "text": "Lungs illustration",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Illustration",
              "slug": "illustration",
              "status": "active",
              "canonId": "019de52c-fe76-7772-a5ac-c0b7294d7615",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "illustration",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.577+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "32c9b4ee-3b3c-44cd-8ed2-5ac1196c83a5",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.2,
            "w": 0.256,
            "x": 0.064,
            "y": 0.615
          },
          "kind": "image",
          "text": "Mast cell illustration",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Image",
              "slug": "image",
              "status": "active",
              "canonId": "019de52c-f978-701f-a720-51d029d769e7",
              "version": 1,
              "description": "Photo, illustration, screenshot or icon."
            },
            "tool": null,
            "subkind": {
              "name": "Illustration",
              "slug": "illustration",
              "status": "active",
              "canonId": "019de52c-fe76-7772-a5ac-c0b7294d7615",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "illustration",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.577+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "d8ebe98d-dadb-4a04-93d5-36458a395c6e",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.48,
            "w": 0.554,
            "x": 0.382,
            "y": 0.318
          },
          "kind": "list",
          "text": "Prevalence: ~5-10% of all asthma patients; estimated 750K – 1 million patients in US; adult population ~60% female, mean age ~50 years\nDefinition: disease not sufficiently controlled with standard nonbiologic treatments; reduced lung function, higher incidence of exacerbations\nMast cells shown to play a central role: in both regulation of both lower airway inflammation and airway hyperresponsiveness\nCurrent oral treatment options are limited: multiple approved biologics, but no new oral therapy approved for asthma since anti-leukotrienes in late 1990s\nNew oral treatment options with the potential to treat across all severe asthma endotypes are needed",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.577+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "c3b61895-497f-4b22-afbf-a45f849d1405",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.026,
            "w": 0.733,
            "x": 0.036,
            "y": 0.128
          },
          "kind": "title",
          "text": "Limited oral treatment options for patients beyond corticosteroids and anti-leukotrienes",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Action title",
              "slug": "action-title",
              "status": "active",
              "canonId": "019de52c-fb31-734c-a0f5-a3935b73135d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "action-title",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.577+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "cff21286-e426-4ace-8b4e-d10195f7acc4",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.044,
            "w": 0.431,
            "x": 0.036,
            "y": 0.068
          },
          "kind": "title",
          "text": "Severe Asthma Disease Overview",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.577+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e5fa3ac7-cfa7-4838-aab6-86764276b437",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [
        {
          "tool": {
            "name": "Problem Statement Canvas",
            "slug": "problem-statement-canvas",
            "status": "active",
            "bestFor": null,
            "canonId": "019dd956-839d-744b-ad11-9bf3e3642a18",
            "version": 1,
            "bodyDocId": null,
            "description": "Structured definition of the problem: What? Who? Where? When? Scale?",
            "familyLabel": null,
            "categoryName": "Block",
            "categorySlug": "block"
          },
          "agent": "Architect",
          "layer": "slide",
          "agents": [
            "Architect"
          ],
          "matchId": "8e4611e9-b1cc-4e68-af16-eff831bb4a51",
          "evidence": "The slide presents a problem statement with disease overview, limited treatment options, and statistics, which matches the problem statement canvas.",
          "pageRefs": null,
          "priority": null,
          "whenToUse": null,
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-17 00:10:59.207447+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "pageNumber": 21,
          "whyItWorks": null,
          "antipattern": null,
          "cardinality": null,
          "narrativePurpose": null
        }
      ],
      "frameworks": [],
      "arcBeats": [
        {
          "to": 21,
          "arc": {
            "name": "The Sequoia Pitch",
            "slug": "sequoia-pitch",
            "status": "active",
            "bestFor": "Investor pitches, Series A/B, board presentations",
            "canonId": "019dd956-5e69-75a7-a0a4-895ac1bc0444",
            "version": 1,
            "bodyDocId": "019df22a-2356-73eb-8061-d8c81dc0aa49",
            "structure": "Problem -> Solution -> Why Now -> Market Size -> Competition -> Product -> Business Model -> Team -> Financials -> The Ask",
            "description": null,
            "familyLabel": null
          },
          "from": 20,
          "name": "Market Size",
          "beatId": "3071eeb1-d844-41d8-a60d-a94623bcd39f",
          "matchId": "94ff7873-4417-4ff8-ad34-e79157dbce25",
          "beatType": {
            "name": "Market Size",
            "slug": "sequoia-pitch-market-size",
            "status": "active",
            "canonId": "019dd9b8-20e6-729c-bc28-05442906d032",
            "version": 1,
            "description": null
          },
          "evidence": "The deck presents an overview of the market size on pages 20 and 21, discussing chronic urticaria and severe asthma.",
          "position": 2,
          "isPrimaryArc": true,
          "parentBeatType": {
            "name": "Evidence",
            "slug": "evidence",
            "status": "active",
            "canonId": "019dd9b8-03f9-772a-b84a-4f07b415b77a",
            "version": 1,
            "description": "A dedicated proof beat exists in only ~4 arcs (Gambit, Sequoia, AIDA, Monroes). Other arcs embed evidence inline within development."
          },
          "alignedBlockIds": null,
          "matchConfidence": 0.8
        }
      ],
      "loops": [
        {
          "to": 21,
          "from": 5,
          "loop": {
            "name": "27_cost_of_inaction",
            "slug": "27-cost-of-inaction",
            "status": "active",
            "bestFor": "Urgent budget requests, compliance, risk mitigation",
            "canonId": "019dd956-70d1-7395-a15b-857ba858b394",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Status Quo -> The Hidden Costs Accumulating -> The Future State of Inaction -> The Tipping Point",
            "description": "Quantify what happens if the audience does nothing",
            "familyLabel": null
          },
          "matchId": "1637e937-fd9b-4682-939c-d684884ac925",
          "evidence": "The deck presents the limitations of current treatments and the potential benefits of THB001.",
          "position": 0,
          "objective": "What is the cost of not treating mast cell-mediated diseases effectively?",
          "confidence": 0.7,
          "extraction": {
            "at": "2026-07-16 22:26:33.613276+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        },
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 22,
      "type": "analysis",
      "title": "DART stands for developmental and reproductive toxicology.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 68,
        "componentCount": 6,
        "textChars": 951,
        "nDataPoints": 0,
        "notes": "DART stands for developmental and reproductive toxicology.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.794+00",
          "seconds": 3.102,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/22",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-22",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.1,
            "w": 0.5,
            "x": 0.25,
            "y": 0.85
          },
          "kind": "callout",
          "text": "No evidence of structural or off-target liabilities; on-target effects believed to be reversible",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Callout",
              "slug": "callout",
              "status": "active",
              "canonId": "019de52c-f8d3-761a-8953-7d37080de5e2",
              "version": 1,
              "description": "Highlighted callout box."
            },
            "tool": null,
            "subkind": {
              "name": "Primary callout",
              "slug": "primary",
              "status": "active",
              "canonId": "019de52c-fbd1-70eb-a9ce-8997f8674c1d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "primary",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "47d23cfd-b39b-4fb9-a432-03f7ec8264e4",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.3,
            "x": 0.03,
            "y": 0.27
          },
          "kind": "list",
          "text": "Safety Pharmacology & Genotoxicity Studies: No findings anticipated to be of clinical relevance from a standard battery of nonclinical CNS, CV and respiratory safety pharmacology studies; Negative for genotoxicity; Negative for photoirradiation potential",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0d3575e8-63c6-4ab5-8c6b-d5c577fac09e",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.3,
            "x": 0.35,
            "y": 0.27
          },
          "kind": "list",
          "text": "Repeat Dose Toxicology Studies: Anticipated on-target effects related to KIT inhibition observed on spermatogenesis, hematology and pigmentation; Complete reversibility for these effects either observed or we believe can be achieved with a sufficient recovery period",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "267bb5a2-c934-4923-a08b-0bc1616ea241",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.35,
            "w": 0.3,
            "x": 0.67,
            "y": 0.27
          },
          "kind": "list",
          "text": "Ongoing Toxicology Program: Rat and dog chronic toxicology studies ongoing to support Phase 2 open label extension studies; DART program initiated, teratogenicity labeling expected with KIT inhibition, as with other immunology drug classes",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "45ded190-561f-4f52-aae7-6714d9a51484",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.03,
            "w": 0.25,
            "x": 0.67,
            "y": 0.64
          },
          "kind": "source-note",
          "text": "DART: developmental and reproductive toxicology",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Source note",
              "slug": "source-note",
              "status": "active",
              "canonId": "23484952-494b-4a5e-b1ad-550d0d70e948",
              "version": 1,
              "description": "Attribution / source / caveat placed at the slide footer. Numbered footnotes use attrs.numbered."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "71583f62-d815-4a77-9d22-59a78e2f9c8b",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.45,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "THB001: Nonclinical Safety and Toxicology Profile",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.794+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "4c33be8d-4df7-483e-a25d-b074ef6aaf05",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 23,
      "type": "analysis",
      "title": "SAD = Single Ascending Dose; FE = Food Effect; PK = Pharmacokinetics; SAE = Serious Adverse Event; AE = Adverse Event; PBO = Placebo.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 59,
        "componentCount": 5,
        "textChars": 459,
        "nDataPoints": 12,
        "notes": "SAD = Single Ascending Dose; FE = Food Effect; PK = Pharmacokinetics; SAE = Serious Adverse Event; AE = Adverse Event; PBO = Placebo.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:20.654+00",
          "seconds": 2.91,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/23",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-23",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.5,
            "w": 0.32,
            "x": 0.65,
            "y": 0.18
          },
          "kind": "chart",
          "text": "Single Dose PK: THB001 concentration (ng/mL) over time by dose",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.654+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "8f7dab1c-797b-44a0-bea2-19ed97e2f95f",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.15,
            "w": 0.32,
            "x": 0.65,
            "y": 0.75
          },
          "kind": "list",
          "text": "Dose proportional increases (10-300mg); Mean half-life ~24 hrs; No negative food effect.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.654+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a4fbfc5c-2109-4174-9e61-01007d6524ac",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.25,
            "w": 0.6,
            "x": 0.03,
            "y": 0.6
          },
          "kind": "list",
          "text": "No SAEs; One moderate AE (Rash); No early terminations; No dose escalation/stopping criteria met; No significant changes in vitals/labs.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "List",
              "slug": "list",
              "status": "active",
              "canonId": "019de52c-f94b-779b-a53b-fd4904a5f4d2",
              "version": 1,
              "description": "Bullet or numbered list."
            },
            "tool": null,
            "subkind": {
              "name": "Bullet list",
              "slug": "bullet",
              "status": "active",
              "canonId": "019de52c-fc98-7169-a083-5cab805076ca",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "bullet",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.654+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "b4f1d70c-d0d5-45b0-96d9-b10508589f26",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.3,
            "w": 0.6,
            "x": 0.03,
            "y": 0.2
          },
          "kind": "table",
          "text": "SAD/FE Treatment Emergent Adverse Events table showing counts and percentages for Headache, Fatigue, Myalgia, and Dizziness across dose groups.",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Table",
              "slug": "table",
              "status": "active",
              "canonId": "019de52c-f9c8-7148-8119-eaac9594cd28",
              "version": 1,
              "description": "Tabular data layout."
            },
            "tool": null,
            "subkind": {
              "name": "Data table",
              "slug": "data",
              "status": "active",
              "canonId": "019de52d-02d5-75b8-8abf-88e92bf63569",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "data",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.654+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "1f33d403-1626-45bc-b131-514b291d05ae",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.45,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "SAD & FE Safety and PK Summary",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:20.654+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0261a525-38c5-4ac3-947b-2d67707038d1",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    },
    {
      "page": 24,
      "type": "analysis",
      "title": "MAD = Multiple Ascending Dose study. Data shows transient changes in reticulocytes and hemoglobin levels during treatment.",
      "function": "analyze_data",
      "rawType": "appendix_data",
      "block": null,
      "metadata": {
        "slideType": "appendix_data",
        "slideTypeCanon": {
          "name": "Appendix data",
          "slug": "appendix_data",
          "status": "active",
          "canonId": "019de52d-078a-745b-9ee4-c15f2f539acd",
          "version": 1,
          "description": null
        },
        "function": "analyze_data",
        "functionCanon": {
          "name": "Analyze data",
          "slug": "analyze_data",
          "status": "active",
          "canonId": "019de52d-1590-7413-8c82-cc218cff40b4",
          "version": 1,
          "description": null
        },
        "density": "dense",
        "densityScore": 52,
        "componentCount": 5,
        "textChars": 312,
        "nDataPoints": 100,
        "notes": "MAD = Multiple Ascending Dose study. Data shows transient changes in reticulocytes and hemoglobin levels during treatment.",
        "elementsJson": null,
        "confidence": 1,
        "extraction": {
          "model": "google/gemini-3.1-flash-lite-preview-20260303",
          "runId": null,
          "at": "2026-05-02 12:28:21.949+00",
          "seconds": 3.84,
          "promptVersion": "v2-canon-conditioned"
        }
      },
      "links": {
        "slide": "/slides/019de073-9947-75c9-ab6d-01a31b39af7e/24",
        "deck": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e",
        "deckAnchor": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e#slide-24",
        "deckJson": "/decks/019de073-9947-75c9-ab6d-01a31b39af7e.json"
      },
      "components": [
        {
          "bbox": {
            "h": 0.6,
            "w": 0.45,
            "x": 0.52,
            "y": 0.2
          },
          "kind": "chart",
          "text": "Hemoglobin over time",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.949+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0fc34e27-8c1a-43b3-b356-b9219ccfdc84",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.6,
            "w": 0.45,
            "x": 0.03,
            "y": 0.2
          },
          "kind": "chart",
          "text": "Reticulocytes over time",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Chart",
              "slug": "chart",
              "status": "active",
              "canonId": "019de52c-f9a0-76ef-adc6-0b859109d1f8",
              "version": 1,
              "description": "Quantitative chart."
            },
            "tool": null,
            "subkind": {
              "name": "Line chart",
              "slug": "line",
              "status": "active",
              "canonId": "019de52c-ff62-778f-8f6c-a952ceae8677",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "line",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.949+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "330bd335-51e8-4643-9bac-1f7573708d22",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.04,
            "w": 0.5,
            "x": 0.25,
            "y": 0.94
          },
          "kind": "disclaimer",
          "text": "F ULN= female upper limit of normal; F LLN=female lower limit of normal, M ULN = male upper limit of normal; M LLN = male lower limit of normal; Mean ± SD",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Disclaimer",
              "slug": "disclaimer",
              "status": "active",
              "canonId": "91173477-d91f-4024-bbaf-d4f93e3f82dc",
              "version": 1,
              "description": "Legal/cautionary text that occupies most of the body of its slide."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.949+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "e513ed97-37cb-48a5-bea6-e08613db65ca",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.08,
            "w": 0.5,
            "x": 0.25,
            "y": 0.82
          },
          "kind": "legend",
          "text": "Placebo, 200mg QD, 200mg Q12H, 400mg Q12H, 500mg QD FED",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Legend",
              "slug": "legend",
              "status": "active",
              "canonId": "31361933-3d22-4c70-bbad-0801e9fffc0c",
              "version": 1,
              "description": "Color/symbol decoder placed adjacent to a chart or diagram."
            },
            "tool": null,
            "subkind": null,
            "framework": null
          },
          "subkind": null,
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.949+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "a82edd35-a299-4bf7-9079-56ee39d101ef",
          "parentComponentId": null
        },
        {
          "bbox": {
            "h": 0.05,
            "w": 0.5,
            "x": 0.03,
            "y": 0.06
          },
          "kind": "title",
          "text": "MAD Hematology Panel (Erythro lineage): Mean Result (+/- SD)",
          "attrs": null,
          "canon": {
            "kind": {
              "name": "Title",
              "slug": "title",
              "status": "active",
              "canonId": "019de52c-f7dd-76d9-b848-b1f12bd85cf4",
              "version": 1,
              "description": "Slide title or headline."
            },
            "tool": null,
            "subkind": {
              "name": "Headline",
              "slug": "headline",
              "status": "active",
              "canonId": "019de52c-fae1-7463-9a7c-d60668eced0d",
              "version": 1,
              "description": null
            },
            "framework": null
          },
          "subkind": "headline",
          "groupRole": null,
          "confidence": null,
          "extraction": {
            "at": "2026-05-02 12:28:21.949+00",
            "model": "google/gemini-3.1-flash-lite-preview-20260303",
            "runId": null,
            "seconds": null,
            "promptVersion": null
          },
          "componentId": "0da2cc68-e210-48b8-8bbe-8f7babda0da4",
          "parentComponentId": null
        }
      ],
      "metrics": [],
      "tools": [],
      "frameworks": [],
      "arcBeats": [],
      "loops": [
        {
          "to": 24,
          "from": 18,
          "loop": {
            "name": "47_quick_win_big_bet",
            "slug": "47-quick-win-big-bet",
            "status": "active",
            "bestFor": "Transformation planning, 100-day plans, resource allocation",
            "canonId": "019dd956-790d-708d-983e-ef9bbc68f741",
            "version": 1,
            "bodyDocId": "019df22a-2420-77be-bc41-ded96d08cb21",
            "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
            "description": "Separate initiatives into immediate wins and longer-term strategic bets",
            "familyLabel": null
          },
          "matchId": "f318ece6-0617-4060-a8a8-460a299bc4cc",
          "evidence": "The deck presents multiple upcoming clinical catalysts and a clear development plan.",
          "position": 1,
          "objective": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?",
          "confidence": 0.6,
          "extraction": {
            "at": "2026-07-16 22:26:33.648143+00",
            "model": "or:meta-llama/llama-4-scout",
            "runId": null,
            "seconds": null,
            "promptVersion": "doc-narrative-v1"
          }
        }
      ],
      "locked": true
    }
  ],
  "arcBeats": [
    {
      "from": 5,
      "to": 6,
      "label": "Problem",
      "description": "The deck presents the problem statement on pages 5 and 6, highlighting the role of mast cells in allergy and inflammation."
    },
    {
      "from": 7,
      "to": 8,
      "label": "Solution",
      "description": "The deck presents the solution on pages 7 and 8, introducing THB001 as a highly selective oral wild-type KIT inhibitor."
    },
    {
      "from": 20,
      "to": 21,
      "label": "Market Size",
      "description": "The deck presents an overview of the market size on pages 20 and 21, discussing chronic urticaria and severe asthma."
    }
  ],
  "loops": [
    {
      "from": 5,
      "to": 21,
      "label": "Cost Of Inaction",
      "description": "What is the cost of not treating mast cell-mediated diseases effectively?"
    },
    {
      "from": 18,
      "to": 24,
      "label": "Quick Win Big Bet",
      "description": "Can THB001 achieve quick wins and make a big impact in the treatment of mast cell-mediated diseases?"
    }
  ]
}