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      "description": "The genetics startup CAMP4 Therapeutics just raised a $100 million Series B round. The company hopes to treat disease by drugging a neglected area of the human genome. The Massachusetts biotech aims to start human testing in 2023.  A biotech in Cambridge;; Massachusetts;; raised $100 million to explore what its leaders call the \"dark side\" of the genome.  On Wednesday;; CAMP4 Therapeutics announced its Series B round;; which it said would help it start initial human testing next year. The startup;; named after the camp closest to Mount Everest's summit;; was founded in 2016 and is researching a special type of RNA called regulatory RNA.  There are multiple types of RNA. The best-known type is messenger RNA — the basis of the Pfizer and Moderna COVID-19 vaccines — which acts as a courier within the cell to carry instructions about how to make proteins from DNA.  Regulatory RNA;; or regRNA;; is part of the 98% of the human genome sequence that doesn't make proteins;; said David Bumcrot;; CAMP4's chief scientific officer. Instead;; these molecules control the expression of the protein-making genes.  Building off research from Rick Young;; an MIT researcher who cofounded CAMP4;; the company is shining a light on this neglected part of the genome;; its leaders said. The company plans to design drugs to bind to regRNA;; effectively controlling how much of a protein is made.  Its CEO;; Josh Mandel-Brehm;; says the company's platform can be applied to more than 1;;000 genetic diseases. The startup hopes to ask regulators in early 2023 to start human testing for its lead drug candidate: a therapy for Dravet syndrome;; a rare genetic disorder. Mandel-Brehm said that CAMP4 is also prioritizing partnerships and that early talks are ongoing with Big Pharma.  \"Now that this fundraise is in the bank;; we are ready to partner and we are absolutely focused on putting at least one major partnership in place;;\" he said;; adding that he hopes to strike a partnership deal in the next six to nine months.  See the 18-slide pitch deck CAMP4 used to raise money from VCs including Patient Square Capital;; Andreessen Horowitz;; and 5AM Ventures.",
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